Article
Chemistry, Analytical
Joshua Reyes-Morales, Matthew W. Glasscott, Andrew D. Pendergast, Sondrica Goines, Jeffrey E. Dick
Summary: Investigated reactivity at the three-phase boundary, revealing that ion transfer mechanisms are highly dependent on droplet size and the presence of an ionic liquid.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Paulina Borgul, Patrycja Pawlak, Konrad Rudnicki, Karolina Sipa, Pawel Krzyczmonik, Anna Trynda, Slawomira Skrzypek, Gregoire Herzog, Lukasz Poltorak
Summary: In this work, ephedrine was studied at the electrified liquid-liquid interface using a micro-punched array of apertures in a self-adhesive polyimide tape. By controlling the penetration depth and utilizing ion transfer voltammetry, ephedrine sensing was achieved with a detection limit of 1 μM. The best results were obtained with a membrane containing 12 micro-punched pores made with the highest studied penetration depth of 1450 μm.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Gazi Jahirul Islam, Damien W. M. Arrigan
Summary: This research investigates the detection of four PFAS substances using ion transfer voltammetry at micropipette-based interfaces between two immiscible electrolyte solutions (mu ITIES). The study finds that all four PFAS substances can be detected by ion transfer voltammetry at the mu ITIES, with selectivity for detecting most combinations of the compounds. These findings provide a basis for the design of new PFAS sensing strategies based on ion transfer voltammetry.
Article
Biochemistry & Molecular Biology
Shaheda Zannah, Damien W. M. Arrigan
Summary: The electrochemistry of catalase (CAT) was investigated at the liquid-liquid interface, demonstrating its electroactive nature under specific conditions. Analysis of CAT's electrochemical behavior in a micro-interface array format allows for its detection and characterization at the interface.
BIOELECTROCHEMISTRY
(2021)
Article
Engineering, Environmental
Lukasz Poltorak, Konrad Rudnicki, Viliam Kolivoska, Tana Sebechlebska, Pawel Krzyczmonik, Slawomira Skrzypek
Summary: In this study, the electrochemical behavior of ephedrine at the polarized liquid-liquid interface was investigated using a specially designed electrochemical cell. It was found that ephedrine undergoes reversible ion transfer reaction and can be detected using ion transfer voltammetry. Additionally, analysis of ion partition diagram provided valuable pharmacochemical information.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Paulina Borgul, Karolina Sobczak, Konrad Rudnicki, Andrzej Leniart, S. lawomira Skrzypek, Lukasz Poltorak
Summary: In this study, a thin porous aluminum film was thermally oxidized and used as a support for the electrified liquid-liquid interface. The constructed platform showed significant voltammetric characteristic for the forward interfacial transport of model ions. The utility of the device was verified for voltammetric norcocaine sensing.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Review
Chemistry, Physical
Eduardo Laborda, Angela Molina
Summary: In the field of single-entity electrochemistry, the use of soft interfaces has been proven to be a valuable complement to solid microelectrodes for both hard and soft micro- and nanoparticles. This approach also offers a new platform for studying electronic and ionic transfers across liquid-liquid interfaces, with applications in biological, technological, and industrial systems. Experimental results with Interfaces between Two Immiscible Electrolyte Solutions (ITIES) are reviewed and discussed in relation to theoretical treatments.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Article
Electrochemistry
Paulina Borgul, Karolina Sobczak, Konrad Rudnicki, Piotr Glazer, Patrycja Pawlak, Anna Trynda, Slawomira Skrzypek, Lukasz Poltorak
Summary: The study utilized cyclic voltammetry to investigate the behavior of cocaine cutting agents at the electrified liquid-liquid interface, identifying detectable chemicals and extracting electroanalytical parameters and diffusion coefficients to aid in the development of cocaine sensors for detecting the drug in complex street samples.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Yang Liu, Reza Moshrefi, William D. A. Rickard, Micheal D. Scanlon, T. Jane Stockmann, Damien W. M. Arrigan
Summary: The electrochemical behavior of hexagonally arranged nanopore arrays was studied, revealing larger steady-state currents and diffusion limits compared to previously reported square-patterned arrays, indicating the need for new design criteria to achieve independent diffusion.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Electrochemistry
Qiao Liu, Liang Liu, Michel Perdicakis, Alain Walcarius
Summary: This study presents a new approach to electrochemical stripping analysis, where the target analyte is indirectly analyzed based on the signal obtained from the counter electrode, using an ultramicroelectrode to take advantage of the polarization effect. By utilizing this method, the resolution of signals can be improved and background interference can be reduced, offering a new angle of electroanalysis.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Shi-Hua Chen, Zong-Yin Song, Xiang-Yu Xiao, Hong-Qi Huang, Yuan-Fan Yang, Pei-Hua Li, Meng Yang, Xing-Jiu Huang
Summary: Vacancy and doping engineering were used to improve the electrocatalytic ability of nanomaterials for detecting heavy metal ions. The P-doped material showed enhanced sensitivity and selectivity towards As(III), and the vacancies provided abundant electrons to form active centers.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Vladislav Poklonnov, Leonid Martynov, Artem Astafiev, Nikolay Zaitsev
Summary: The study focused on the simple and facilitated transfer of tripeptide glutathione across the water/2-nitrophenyl octhyl ether interface using cyclic voltammetry at the interface between two immiscible electrolyte solutions. A micro-perforated membrane was utilized for mechanical stabilization of the interface. The method of square wave voltammetry based on facilitated transfer allowed for accurate determination of glutathione with a low detection limit and wide linear dynamic range, which was applied to determine glutathione in aqueous solutions and malt extract.
Article
Electrochemistry
Tamara A. Hernandez, Fabricio Mayorga, Julia Garcia, Franco M. Zanotto, Ricardo A. Fernandez, Sergio A. Dassie
Summary: We present a model that describes the facilitated transfer of two cations across liquid|liquid interfaces in the presence of a neutral weak acid and its conjugate base. The mechanism of ion transfer can be identified by measuring the peak-to-peak potential difference and the dependence of transfer potential with pH. Furthermore, a set of equations is derived to locate each experimental condition within a pH-potential diagram based on the hydrophobicity of the ligand.
Article
Chemistry, Physical
K. Krishna Kumar, M. Devendiran, R. A. Kalaivani, S. Sriman Narayanan
Summary: Curcumin, a natural ligand, was successfully converted into nanosphere-shaped polycurcumin film using electropolymerization, enabling the detection of Hg2+ ions. Parameters were optimized for selective determination of Hg2+ ions, with a linear concentration range from 0.21 to 21.72 mu gL-1, and a LOD of 70.49 ngL-1.
CHEMICAL PHYSICS LETTERS
(2021)
Article
Chemistry, Analytical
Leonid Yu. Martynov, Anastasia S. Sergeeva, Konstantin A. Sakharov, Valery M. Shkinev, Nikolai A. Yashtulov, Nikolai K. Zaitsev
Summary: This work describes the development of a phosphate-selective electrode with a plasticized membrane containing bis(2-ethylhexyl)tin (IV) dichloride as an ionophore. The membrane showed a linear potential response to HPO42- ions in the concentration range from 4×10-5 to 3×10-2 mol/L with a Nernst slope of 29±2 mV decade-1 activity. Using cyclic voltammetry, the ionophore-facilitated transfer of mono- and dihydro phosphate ions was characterized at the water/PVC-2-nitrophenyl octyl ether phase interface. Alternating current voltammetry was used for quantifying phosphate ions in aqueous solutions.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Mahreen Arooj, Damien W. M. Arrigan, Ricardo L. Mancera
JOURNAL OF PHYSICAL CHEMISTRY B
(2019)
Article
Chemistry, Analytical
Marta Podrazka, Emilia Witkowska Nery, Terence G. Henares, Martin Jonsson-Niedziolka, Damien W. M. Arrigan
ANALYTICAL CHEMISTRY
(2020)
Article
Electrochemistry
Shaghraf Javaid, Junqiao Lee, M. Veronica Sofianos, Zac Douglas-Moore, Damien W. M. Arrigan, Debbie S. Silvester
Summary: This study demonstrated the electrochemical detection of MePa using a ZnO nanoparticle modified glassy carbon electrode. Three different morphologies of ZnO nanoparticles were synthesized by controlling the pH of the reaction solution. Among them, ZnO nanowires showed the best response, with the highest sensitivity and lowest limit of detection under optimal conditions.
Article
Biochemistry & Molecular Biology
Shaheda Zannah, Damien W. M. Arrigan
Summary: The electrochemistry of catalase (CAT) was investigated at the liquid-liquid interface, demonstrating its electroactive nature under specific conditions. Analysis of CAT's electrochemical behavior in a micro-interface array format allows for its detection and characterization at the interface.
BIOELECTROCHEMISTRY
(2021)
Article
Chemistry, Analytical
Hum Bahadur Lamichhane, Terence G. Henares, Mark J. Hackett, Damien W. M. Arrigan
Summary: Understanding protein interactions at interfaces, particularly using experimental methods such as ITIES, can provide insights into how protein structure is influenced by interactions at interfaces. In this study, the destabilization of native insulin secondary structure and the promotion of helix secondary structures at interfaces were found to be driven by protein-interface interactions, highlighting the potential of ITIES as a tool for studying protein structure and interactions.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Magdalena Kaliszczak, Pierrick Durand, Emmanuel Wenger, Manuel Dossot, Franca Jones, Damien W. M. Arrigan, Gregoire Herzog
Summary: Controlled formation of cocrystals of caffeine and 1-hydroxy-2-naphthoic acid was achieved at the interface between two immiscible electrolyte solutions under chemical polarisation, leading to the selective cocrystallisation as confirmed by X-ray diffraction and Raman spectroscopy. Positive interfacial potentials favored the formation of a specific polymorphic form of caffeine:1-hydroxy-2-naphthoic acid cocrystal. This electrochemically controlled cocrystallisation approach opens up new possibilities for drug development.
Article
Chemistry, Analytical
Yang Liu, Reza Moshrefi, William D. A. Rickard, Micheal D. Scanlon, T. Jane Stockmann, Damien W. M. Arrigan
Summary: The electrochemical behavior of hexagonally arranged nanopore arrays was studied, revealing larger steady-state currents and diffusion limits compared to previously reported square-patterned arrays, indicating the need for new design criteria to achieve independent diffusion.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Electrochemistry
Xinyu Li, Surbhi Sharma, Damien W. M. Arrigan, Debbie S. Silvester
Summary: This study directly compares cobalt sulfide nanostructure-based electrodes prepared by two different methods for electrochemical water splitting and glucose sensing. The results show that the electrode prepared by electrodepositing cobalt sulfide demonstrates better performance in oxygen evolution reaction and glucose detection compared to the electrode prepared by hydrothermal method.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Review
Engineering, Electrical & Electronic
Fareeha Arshad, Damien W. M. Arrigan, Minhaz Uddin Ahmed
Summary: This article presents the recent advances in nanozyme based biosensors and discusses the challenges in this field. Studies have shown that synthetic enzyme-based biosensors can effectively detect various clinical biomarkers, thus having the potential to replace conventional testing methods.
IEEE SENSORS JOURNAL
(2022)
Article
Electrochemistry
Magdalena Kaliszczak, Imane Bamou, Marina Garcia-Atance, Franca Jones, Damien W. M. Arrigan, Gregoire Herzog
Summary: This study demonstrates the simultaneous measurement of potential and current variations at the interface between two immiscible electrolyte solutions, using tetraalkylammonium cations as a common ion. The experimental setup is used to investigate the interfacial cocrystallisation process of hydrophilic, cationic caffeine with lipophilic 1-hydroxy-2-naphtoic acid.
Article
Electrochemistry
Terence G. Henares, Julian D. Gale, Gregoire Herzog, Damien W. M. Arrigan
Summary: This study investigated the hydrolysis of pyrosulfate using ion-transfer electrochemistry at microinterfaces. The hydrolysis of pyrosulfate to hydrogen sulfate and sulfate was confirmed by pH measurements and Raman spectroscopy. The ion-transfer potential measurement and quantum mechanical calculations supported the experimentally observed trends and provided thermodynamic analysis for the reactions of pyrosulfate.
Article
Chemistry, Multidisciplinary
Gazi Jahirul Islam, Damien W. M. Arrigan
Summary: This research investigates the detection of four PFAS substances using ion transfer voltammetry at micropipette-based interfaces between two immiscible electrolyte solutions (mu ITIES). The study finds that all four PFAS substances can be detected by ion transfer voltammetry at the mu ITIES, with selectivity for detecting most combinations of the compounds. These findings provide a basis for the design of new PFAS sensing strategies based on ion transfer voltammetry.
Review
Chemistry, Physical
Hum Bahadur Lamichhane, Damien W. M. Arrigan
Summary: This review discusses the electroanalytical detection of PFAS, focusing on approaches such as molecularly imprinted polymers, metal-organic frameworks, interfacial processes, and ion-transfer events. While significant progress has been made in the electroanalytical chemistry of PFAS, further research is needed to improve and establish methods for detecting extremely low concentrations, distinguishing individual PFAS in mixtures, and detecting individual PFAS in various matrix conditions.
CURRENT OPINION IN ELECTROCHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Nazanin Ghaheri, Benjamin J. J. Austen, Gregoire Herzog, Mark Ogden, Franca Jones, Damien W. M. Arrigan
Summary: This study investigates crystallisation at the interface between two immiscible solutions by observing the spontaneous transfer of ions. The results demonstrate the ability to form ionic crystalline materials by exploiting ion transfer processes at the interface between immiscible liquids. The influence of a neutral ionophore in the organic phase on spontaneous formation of BaSO4 was also studied.
Article
Chemistry, Analytical
Benjamin N. Viada, Lidia M. Yudi, Damien W. M. Arrigan
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
