Article
Fisheries
Yue Zhang, Zehong Wei, Mengxi Yang, Danni Liu, Mingzhu Pan, Chenglong Wu, Wenbing Zhang, Kangsen Mai
Summary: This study aimed to investigate the benefits of taurine against oxidative stress, endoplasmic reticulum stress, and inflammation induced by high carbohydrate diet in turbot. Results showed that appropriate taurine supplementation improved antioxidative status and reduced inflammation and ER stress. The optimal dietary taurine content was estimated to be 1.40% based on growth rate analysis. Taurine supplementation attenuated liver inflammation and modulated protein levels related to oxidative stress and inflammation processes induced by high carbohydrate diet.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Cell Biology
Shihab Kochumon, Amal Hasan, Fatema Al-Rashed, Sardar Sindhu, Reeby Thomas, Texy Jacob, Amnah Al-Sayyar, Hossein Arefanian, Ashraf Al Madhoun, Ebaa Al-Ozairi, Fawaz Alzaid, Heikki A. Koistinen, Fahd Al-Mulla, Jaakko Tuomilehto, Rasheed Ahmad
Summary: Chronic low-grade inflammation induced by obesity is a central risk factor for the development of metabolic syndrome. This study found that high LDL-c levels were associated with increased expression of adipose IL-23, suggesting that IL-23 may act as an inflammatory biomarker for disease progression in people with high LDL-c.
Article
Fisheries
Mingzhu Pan, Danni Liu, Jiahuan Liu, Xinxin Li, Dong Huang, Kai Luo, Yue Liu, Zhenhua Wu, Wenbing Zhang, Kangsen Mai
Summary: This study found that high carbohydrate diets caused inflammation and apoptosis in the liver and intestine of turbot. Supplementation of biotin in the diet alleviated these effects. The study provides basic data for the application of biotin in turbot feed.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Kamilla Pedersen, David Hojland Ipsen, Josephine Skat-Rordam, Jens Lykkesfeldt, Pernille Tveden-Nyborg
Summary: This study investigated the effects of high-fat diets based on coconut oil or cocoa butter on glucose homeostasis and NASH in guinea pigs. The results showed that a diet high in long-chain fatty acids (LCFA) promoted metabolic imbalance and accelerated NASH-associated hepatic fibrosis. The study highlights the importance of evaluating fatty acid composition when investigating NASH-related endpoints.
Article
Biochemistry & Molecular Biology
Su Hyeon Kim, Hyun Jeong Yoon, Young Hye Kwon
Summary: The study found that ApoE-/- mice exhibited increased cholesterol accumulation and altered gene expression in white adipose tissue under a high-fat high-cholesterol diet, particularly genes related to inflammatory response. In contrast, wild-type mice showed minimal changes in gene expression.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Physiology
Cynthia R. Muller, Alexander T. Williams, Allyn M. Eaker, Fernando Dos Santos, Andre F. Palmer, Pedro Cabrales
Summary: This study identified a new animal model for diet-induced metabolic disorders in guinea pigs without obesity. The results suggest a strong correlation between liver disease and increased cardiovascular risks.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Nutrition & Dietetics
Lukas Cipryan, Tomas Dostal, Daniel J. Plews, Peter Hofmann, Paul B. Laursen
Summary: This study demonstrates that in healthy young individuals, consuming a very low-carbohydrate, high-fat diet combined with regular exercise over a 12-week period can lead to reductions in body weight and fat mass, along with beneficial changes in serum adiponectin and leptin concentrations, supporting the use of this dietary strategy for the prevention of chronic diseases associated with systemic low-grade inflammation.
NUTRITION RESEARCH
(2021)
Article
Agriculture, Dairy & Animal Science
Edith J. Mayorga, Erin A. Horst, Mohmmad Al-Qaisi, Brady M. Goetz, Megan A. Abeyta, Sonia Rodriguez-Jimenez, Samantha Lei, Jesus A. Acosta, John F. Patience, Mariana C. Rossoni Serao, Lance H. Baumgard
Summary: The study found that continuously infusing glucose or casein into the terminal ileum may stimulate a mild immune response, but has little to no effect on blood inflammatory markers, intestinal morphology, or key production parameters.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Lijun Ning, Haotian Zhang, Xiaoying Chen, Jia Zhen, Shen Chen, Junfeng Guang, Chao Xu, Yuanyou Li
Summary: A 12-week trial showed that tilapia has higher tolerance to a high lipid diet than a high carbohydrate diet. Continuous feeding of the high carbohydrate diet impaired tilapia's appetite, weight gain rate, and immune response. Tilapia's distribution of fat may be a risk-avoidance strategy in response to a continuous high lipid diet.
Article
Food Science & Technology
Jing Sun, Halise Gul Akillioglu, Karoline Aasmul-Olsen, Yuhui Ye, Pernille Lund, Xiao Zhao, Anders Brunse, Christian Fiil Nielsen, Dereck E. W. Chatterton, Per Torp Sangild, Marianne N. Lund, Stine Brandt Bering
Summary: This study uses preterm pigs as a model for sensitive newborns and finds that feeding ultra-high temperature treated infant formulas, especially after prolonged storage, adversely affects gut maturation and function, leading to diarrhea and intestinal inflammation.
MOLECULAR NUTRITION & FOOD RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Zhongyang Guo, Xiaoling Chen, Zhiqing Huang, Daiwen Chen, Bing Yu, Hong Chen, Jie Yu, Hui Yan, Ping Zheng, Yuheng Luo
Summary: This study utilized pigs as experimental subjects to investigate the effects of dietary dihydromyricetin (DHM) supplementation on antioxidant capacity and lipid metabolism. Results showed that DHM supplementation improved the antioxidant capacity and lipid metabolism in finishing pigs.
Article
Biochemistry & Molecular Biology
Ines Magro dos Reis, Tom Houben, Marion J. J. Gijbels, Dieter Luetjohann, Jogchum Plat, Ronit Shiri-Sverdlov
Summary: The study found that dietary plant stanol supplementation can reduce liver cholesterol accumulation and improve liver inflammation, especially in mice fed a high fat, high cholesterol diet. However, the effects of plant stanol supplementation on these parameters were less significant in mice fed a low cholesterol diet. Future research should investigate whether other models of metabolic inflammation exhibit similar stanol-related effects on inflammation.
Article
Immunology
Hong-Ying Qiu, Na-Na Zhang, Qing-Qing Ma, Rui-Ting Li, Meng-Yue Guan, Li-Li Zhang, Jia Zhou, Rong-Rong Zhang, Xing-Yao Huang, Wen-Hui Yang, Yong-Qiang Deng, Cheng-Feng Qin, Dong-Sheng Zhou
Summary: This study demonstrates that Zika virus can be transmitted via aerosol routes, resulting in systemic infection and inducing immune responses.
EMERGING MICROBES & INFECTIONS
(2022)
Article
Fisheries
Tong Wang, Hong-Xia Wu, Wei-jie Li, Rong Xu, Fang Qiao, Zhen-Yu Du, Mei -Ling Zhang
Summary: The study showed that supplementing MOS in high carbohydrate diet can improve weight gain and body length in juvenile Nile tilapia, and regulate glucose and lipid metabolism to mitigate the adverse effects.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Nutrition & Dietetics
Parker N. Hyde, Teryn N. Sapper, Richard A. LaFountain, Madison L. Kackley, Alex Buga, Brandon Fell, Christopher D. Crabtree, Stephen D. Phinney, Vincent J. Miller, Sarah M. King, Ronald M. Krauss, William J. Kraemer, Jeff S. Volek
Summary: This study compared the effects of palm stearin and butter consumption on circulating cholesterol levels in healthy subjects on low-carbohydrate/high-fat and high-carbohydrate/low-fat diets. The results showed that butter led to higher LDL cholesterol levels compared to palm stearin, regardless of the background dietary variations, primarily due to larger cholesterol-rich LDL particles.
