In healthy adults, resistant maltodextrin produces a greater change in fecal bifidobacteria counts and increases stool wet weight: a double-blind, randomized, controlled crossover study

Dietary fiber stimulates the growth of potentially beneficial bacteria (eg, bifidobacteria), yet most Americans do not meet daily fiber recommendations. Resistant maltodextrin (RMD), a fermentable functional fiber, may help individuals meet total fiber recommendations and potentially increase bifidobacteria. It was hypothesized that fecal bifidobacteria counts/ng fecal DNA would increase after adding 25 g RMD to inadequate fiber diets of healthy adults. In this double-blind, controlled crossover study, 51 participants (26.3 +/- 6.8 years, mean +/- SD) were randomized to consume 0, 15, and 25 g RMD daily for 3 weeks followed by a 2-week washout. Participants collected all stools for 2 days at weeks 0 and 3 of each intervention for stool wet weight (WW) measurements and fecal bifidobacteria counts. Weekly 24-hour dietary recalls assessed total fiber intake. Only 25 g RMD resulted in a change (final minus baseline) in bifidobacteria that was significant compared with 0 g (0.17 +/- 0.09 vs -0.17 +/- 0.09 log(10)[counts], respectively, mean +/- SEM, P = .008). Stool WW increased only with 25 g (150 +/- 11 vs baseline 121 +/- 11 g/d; P = .011). Mean daily total fiber intake (including RMD) was significantly higher (both P < .001) with 15 g (17.8 +/- 0.6 g/1000 kcal or 4184 kJ) and 25 g (25.3 +/- 1.1 g/1000 kcal) compared with 0 g RMD (8.4 +/- 0.4 g/1000 kcal). Mean daily total fiber intakes exceeded recommendations (14 g/1000 kcal) with 15 and 25 g of RMD, and 25 g RMD increased fecal bifidobacteria counts and stool WW, suggesting health benefits from increasing total fiber intake. (C) 2018 Elsevier Inc. All rights reserved.