Article
Peripheral Vascular Disease
Yiyi Zhang, Joseph E. Schwartz, Byron C. Jaeger, Jaejin An, Brandon K. Bellows, Donald Clark, Aisha T. Langford, Jolaade Kalinowski, Olugbenga Ogedegbe, John Jeffrey Carr, James G. Terry, Yuan-I. Min, Kristi Reynolds, Daichi Shimbo, Andrew E. Moran, Paul Muntner
Summary: The study suggests that higher diastolic BP and asleep SBP may be risk factors for subclinical atherosclerosis, highlighting the potential role of ambulatory BP monitoring in identifying individuals at high risk for coronary artery disease.
Article
Peripheral Vascular Disease
Marwah Abdalla, Shari D. Bolen, Jeffrey Brettler, Brent M. Egan, Keith C. Ferdinand, Cassandra D. Ford, Daniel T. Lackland, Hilary K. Wall, Daichi Shimbo
Summary: This article discusses the implementation strategies to optimize hypertension management and improve blood pressure control among adults in the United States, emphasizing the importance of accurate blood pressure measurement, team-based care, promoting lifestyle changes, and improving medication acceptance and adherence.
Article
Cardiac & Cardiovascular Systems
Ning Ding, Yong Long, Changluo Li, Liudang He, Yingjie Su
Summary: This study found that there was a negative association between uric acid and blood pressure in the hypertension treatment group. In the hypertension non-treatment group, the associations between uric acid and blood pressure exhibited an inverted U-shape.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Peripheral Vascular Disease
Emelina Stambolliu, Anastasios Kollias, Ioanna Bountzona, Angeliki Ntineri, George Servos, Andriani Vazeou, George S. Stergiou
Summary: This study shows that nighttime home blood pressure monitoring is feasible and closely associated with nighttime ambulatory blood pressure in children and adolescents, and similarly associated with preclinical organ damage.
Article
Multidisciplinary Sciences
Hussein Alhawari, Sameeha AlShelleh, Hussam Alhawari, Reem Akiely, Bayan Abdallah, Nada Hajjaj, Saja Alkhalaileh, Saif Aldeen AlRyalat
Summary: In this study, a higher prevalence of hypertension and depression was found among medical students. There was an association between higher depression scores and higher diastolic blood pressure. These findings emphasize the importance of comprehensive screening for hypertension and depression among both patient groups.
Review
Environmental Sciences
Hamed Aramjoo, Morteza Arab-Zozani, Ali Feyzi, Ali Naghizadeh, Michael Aschner, Abolfazl Naimabadi, Tahereh Farkhondeh, Saeed Samarghandian
Summary: This study used a systematic and meta-analysis approach to investigate the association between cadmium exposure and blood pressure/hypertension. The findings suggest a positive relationship between blood and hair cadmium levels and hypertension, and indicate that hair is the optimal biological sample for assessing this relationship for both genders.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Peripheral Vascular Disease
Sayuri Tokioka, Naoki Nakaya, Kumi Nakaya, Mana Kogure, Rieko Hatanaka, Ippei Chiba, Ikumi Kanno, Kotaro Nochioka, Hirohito Metoki, Takahisa Murakami, Michihiro Satoh, Tomohiro Nakamura, Mami Ishikuro, Taku Obara, Yohei Hamanaka, Masatsugu Orui, Tomoko Kobayashi, Akira Uruno, Eiichi N. Kodama, Satoshi Nagaie, Soichi Ogishima, Yoko Izumi, Nobuo Fuse, Shinichi Kuriyama, Atsushi Hozawa
Summary: Depressive symptoms are associated with masked hypertension and may be one of its risk factors.
HYPERTENSION RESEARCH
(2023)
Article
Environmental Sciences
Li-Zi Lin, Fan Su, Qiu-Ling Fang, Hung Chak Ho, Yang Zhou, Hui-Min Ma, Duo-Hong Chen, Li-Wen Hu, Gongbo Chen, Hong-Yao Yu, Bo-Yi Yang, Xiao-Wen Zeng, Ming-Deng Xiang, Wen-Ru Feng, Guang-Hui Dong
Summary: This study found that long-term exposure to anthropogenic heat is associated with elevated blood pressure and increased risk of hypertension, with a stronger association observed in female participants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Peripheral Vascular Disease
Keisuke Narita, Satoshi Hoshide, Kazuomi Kario
Summary: This study analyzed the association between home and ambulatory blood pressure monitoring and cardiovascular risk in hypertensive outpatients, and found that both home blood pressure and ambulatory blood pressure were independently associated with cardiovascular risk. Home blood pressure had a modest superiority to predict cardiovascular prognosis compared to ambulatory blood pressure.
Article
Health Care Sciences & Services
C. Barrett Bowling, Richard Sloane, Carl Pieper, Alison Luciano, Barry R. Davis, Lara M. Simpson, Paula T. Einhorn, Suzanne Oparil, Paul Muntner
Summary: Sustained systolic blood pressure control is associated with a lower risk of developing high-cost multimorbidity dyads and triads among Medicare beneficiaries in the ALLHAT study.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2021)
Review
Environmental Sciences
Airton C. Martins, Ana Carolina B. Almeida Lopes, Mariana R. Urbano, Maria de Fatima H. Carvalho, Ana Maria R. Silva, Alexey A. Tinkov, Michael Aschner, Arthur E. Mesas, Ellen K. Silbergeld, Monica M. B. Paoliello
Summary: The study reevaluated the relationship between cadmium exposure and altered blood pressure, finding a positive association between blood cadmium levels and blood pressure and/or hypertension. However, conflicting results and a lack of representative population-based studies of non-smokers leave uncertainty about the association between urinary cadmium and blood pressure and/or hypertension. Additional longitudinal studies are urgently needed to confirm the findings.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Cardiac & Cardiovascular Systems
Giulia Rivasi, Antonella Groppelli, Michele Brignole, Davide Soranna, Antonella Zambon, Grzegorz Bilo, Martino Pengo, Bashaaer Sharad, Viktor Hamrefors, Martina Rafanelli, Giuseppe Dario Testa, Ciara Rice, Rose Anne Kenny, Richard Sutton, Andrea Ungar, Artur Fedorowski, Gianfranco Parati
Summary: This study found that patients with reflex syncope have a higher prevalence of systolic blood pressure drops during ambulatory blood pressure monitoring (ABPM). Cut-off values for these drops were defined, expanding the current indications for ABPM in patients with reflex syncope.
EUROPEAN HEART JOURNAL
(2022)
Article
Health Care Sciences & Services
Linlin Ding, Xinhong Zhu, Zhenfang Xiong, Fen Yang, Xiaona Zhang
Summary: This study investigated the association between age at diagnosis of hypertension and decline in cognitive performance. The study found that hypertension diagnosed in mid-life is associated with worse cognition compared to late life, and longer duration of hypertension is associated with worse memory. Blood pressure control is critical for the preservation of cognitive function.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
Otto Simonsson, Peter S. Hendricks, Robin Carhart-Harris, Hannes Kettner, Walter Osika
Summary: By analyzing the association between lifetime classic psychedelic use and hypertension in the past year among adults in the United States, it was found that individuals who had used tryptamines, a class of classic psychedelics, at least once in their lifetime had significantly lower odds of hypertension. Rigorous randomized controlled trials are needed to further investigate the potential causal pathways of classic psychedelics on blood pressure.
Article
Public, Environmental & Occupational Health
Fatemeh Amiri, Mehdi Moradinazar, Jalal Moludi, Yahya Pasdar, Farid Najafi, Ebrahim Shakiba, Behrooz Hamzeh, Amir Saber
Summary: This study investigated the association between self-reported mobile phone use duration and blood pressure and heart rate. The results showed a significant decrease in systolic and diastolic blood pressure and heart rate in women with longer mobile phone usage.
Article
Medicine, General & Internal
Kevin Bronton, Torgny Wessman, Klas Gransbo, Janin Schulte, Oliver Hartmann, Olle Melander
Summary: This study demonstrates that plasma levels of bio-ADM sampled at ED presentation in patients with acute dyspnea are independently associated with 90-day mortality and hospitalization risk, indicating the need for decongestive therapy.
INTERNAL AND EMERGENCY MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jingxue Pan, Xue Bao, Isabel Goncalves, Amra Jujic, Gunnar Engstrom
Summary: The study found a significant association between skin autofluorescence (AF) and subclinical atherosclerosis in the coronary and carotid arteries. Even after controlling for conventional risk factors, elevated skin AF was still associated with coronary artery calcium score and carotid plaques.
Article
Clinical Neurology
Madeleine Johansson, Artur Fedorowski, Jens Jordan, Gunnar Engstrom, Peter M. Nilsson, Viktor Hamrefors
Summary: This study investigated the relationship between orthostatic blood pressure adaptations, central aortic hemodynamics, and aortic stiffness in a younger population. The findings suggest that altered blood pressure responses to orthostatic challenges are independently and inversely associated with markers of aortic stiffness.
CLINICAL AUTONOMIC RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Francesca Lucca, Valentino Bezzerri, Elisa Danese, Debora Olioso, Denise Peserico, Christian Boni, Giulia Cucchetto, Martina Montagnana, Gloria Tridello, Ilaria Meneghelli, Mirco Ros, Giuseppe Lippi, Marco Cipolli
Summary: This study investigated the immunogenicity and safety of the BNT162b2 vaccine in patients with cystic fibrosis (pwCF) and found that pwCF exhibited a similar immune response to the vaccine as the general population, while lung transplant recipients (LTR) showed impaired immunogenicity, especially in patients undergoing immunosuppressive treatment. The study results highlight the importance of longitudinal assessment of the immune response to COVID-19 vaccination.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Roberta Magliozzi, Anna Pedrinolla, Stefania Rossi, Anna Maria Stabile, Elisa Danese, Giuseppe Lippi, Federico Schena, Massimiliano Calabrese, Massimo Venturelli Venturelli
Summary: The absence or reduction of physical activity and movement can cause problems in various organs/systems. This study found that specific plasma protein signatures can differentiate between chronic bedridden individuals and active individuals. It also suggests that the chronic absence of physical activity may contribute to the dysregulation of complex molecular patterns associated with aging.
Article
Endocrinology & Metabolism
Anita Morandi, Claudia Piona, Massimiliano Corradi, Marco Marigliano, Alice Giontella, Silvia Orsi, Federica Emiliani, Angela Tagetti, Denise Marcon, Cristiano Fava, Claudio Maffeis
Summary: This study aimed to assess the association between overall oxidative stress, oxidized lipoproteins, and glycemic variability with early macro-vascular damage in type 1 diabetes (T1D), in addition to traditional risk factors. The results showed that oxidative stress, gender, insulin dose, diabetes duration, and changes in lipids and blood pressure contributed to the variance of early vascular damage in young patients with T1D.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Article
Clinical Neurology
Jiangming Sun, Yan Borne, Andreas Edsfeldt, Yunpeng Wang, Mengyu Pan, Olle Melander, Gunnar Engstrom, Isabel Goncalves
Summary: This study examines the prognostic and causal roles of mood disorders in strokes. The findings suggest that genetic susceptibilities for mood disorders are associated with increased risk of strokes, and mood disorders have a causal effect on stroke. This can help identify high-risk women early in life and prevent mood disorders and strokes.
Article
Cardiac & Cardiovascular Systems
Xue Bao, Biao Xu, Lars Lind, Gunnar Engstrom
Summary: Subclinical carotid atherosclerosis is an important factor in cardiovascular risk estimation by SCORE2. Carotid ultrasound improves the predictive performance of SCORE2 for cardiovascular risk assessment. SCORE2 may over-predict the risk in individuals without carotid plaque and under-predict the risk in those with carotid plaque.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Annie Brink, Johan Elf, Peter J. J. Svensson, Gunnar Engstrom, Olle Melander, Bengt Zoller
Summary: This study aimed to investigate whether there are sex-specific differences in risk factors for noncancer-related DVT and PE in middle-aged and older individuals. The results showed that anthropometric obesity measures were more strongly associated with DVT and PE in women than in men.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Infectious Diseases
Pasquale De Nardo, Maela Tebon, Alessia Savoldi, Nicola Soriolo, Elisa Danese, Denise Peserico, Matteo Morra, Elisa Gentilotti, Gulser Caliskan, Pierpaolo Marchetti, Riccardo Cecchetto, Annarita Mazzariol, Giuseppe Verlato, Davide Gibellini, Evelina Tacconelli
Summary: This study investigated the diagnostic accuracy of a rapid SARS-CoV-2 Ag test in people experiencing homelessness (PEH) during two pandemic waves. The results showed that the rapid antigen test had reasonable diagnostic accuracy in PEH, which can facilitate early detection and isolation during the COVID-19 pandemic.
INFECTIOUS DISEASES AND THERAPY
(2023)
Article
Clinical Neurology
Elin Dybjer, Atul Kumar, Katarina Nagga, Gunnar Engstrom, Niklas Mattsson-Carlgren, Peter M. Nilsson, Olle Melander, Oskar Hansson
Summary: Dybjer et al. found that the polygenic risk of type 2 diabetes is associated with the risk of dementia, especially vascular dementia. However, further analysis did not support a causal relationship between type 2 diabetes and vascular dementia. It is still unclear whether the genetic risk markers for type 2 diabetes and dementia are the same or if there is a causal link between the two diseases.
BRAIN COMMUNICATIONS
(2023)
Article
Medicine, General & Internal
Simon Timpka, Olle Melander, Gunnar Engstrom, Solve Elmstahl, Peter M. Nilsson, Lars Lind, Mats Pihlsgard, Sofia Enhorning
Summary: This study investigated the association between outdoor temperature and the hormone vasopressin measured through copeptin. The findings showed a J-shaped association between temperature and copeptin concentration, with both low and high temperatures linked to higher copeptin levels. Increasing water intake may be a feasible intervention to lower vasopressin levels and mitigate the adverse health effects of both moderately cold and hot temperatures.
Article
Respiratory System
Bjorn Qvarnstrom, Gunnar Engstrom, Sophia Frantz, Xingwu Zhou, Suneela Zaigham, Johan Sundstrom, Christer Janson, Per Wollmer, Andrei Malinovschi
Summary: This study found that abnormal impulse oscillometry (IOS) is related to increased respiratory symptoms in middle-aged individuals with normal spirometry, especially when resistance and reactance parameters are combined. Further research is needed to investigate the different relationships between respiratory symptoms and reactance and resistance.
Article
Medicine, Research & Experimental
Akshita Gupta, Angelina Konnova, Mathias Smet, Matilda Berkell, Alessia Savoldi, Matteo Morra, Vincent Van Averbeke, Fien H. R. De Winter, Denise Peserico, Elisa Danese, An Hotterbeekx, Elda Righi, Pasquale De Nardo, Evelina Tacconelli, Surbhi Malhotra-Kumar, Samir Kumar-Singh
Summary: In this study, researchers observed the role of host immunity in the emergence of SARS-CoV-2 evasive Spike mutations under therapeutic monoclonal antibody pressure. The results showed that different monoclonal antibody treatments led to the development of mutations, and immunocompromised patients were more likely to develop mutations. The study also found that the neutralizing capacity of the antibodies and T cell immunity were closely related to the development of mutations, and an anti-inflammatory and healing-promoting host environment facilitated mutation development. These data provide evidence for decision-making to reduce the risk of monoclonal antibody treatment failure and improve strategies to mitigate the spread of escape mutants.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Medicine, General & Internal
Simone Romano, Denise Marcon, Lorella Branz, Angela Tagetti, Giada Monami, Alice Giontella, Francesca Malesani, Luca Pecoraro, Pietro Minuz, Milena Brugnara, Cristiano Fava
Summary: Subclinical cardiovascular damage, including increased RWT and high cIMT, is already present in children with ADPKD. RWT is significantly correlated with cDC and PWV, indicating an association between vascular stiffening and cardiac remodeling. It is noteworthy that subclinical cardiovascular damage may occur before a decline in glomerular filtration rate, even in the absence of renal function abnormalities.
MEDICINA-LITHUANIA
(2023)
