Article
Food Science & Technology
Aljaz Medic, Tina Smrke, Metka Hudina, Robert Veberic, Tilen Zamljen
Summary: The aim of this study was to compare the phenolic compositions of bilberry and blueberry liqueurs. 43 compounds were identified, 36 in bilberry liqueur and 21 in blueberry liqueur. Anthocyanins were the major phenolics group in bilberry liqueur, while hydroxycinnamic acids were the most abundant in blueberry liqueur.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Ximena Palma, Samanta Thomas-Valdes, Gonzalo Cruz
Summary: The study shows that acute consumption of blueberries reduces postprandial glucose AUC and increases insulin levels, while supplementation improves insulin sensitivity without significant effects on glucose levels. Additionally, there were no changes in antioxidant capacity observed.
Article
Endocrinology & Metabolism
Camille E. Powe, Joseph J. Locascio, Larraine Huston Gordesky, Jose C. Florez, Patrick M. Catalano
Summary: The study found that Stumvoll and AUC(ins)/AUC(glu) are valid OGTT-based measures of insulin secretory response during pregnancy, and can effectively reflect the changes in insulin secretion.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Robert Krikorian, Matthew R. Skelton, Suzanne S. Summer, Marcelle D. Shidler, Patrick G. Sullivan
Summary: Blueberry supplementation may have a role in improving cognition and metabolism, as well as in preventing cognitive decline in middle-aged individuals.
Article
Nutrition & Dietetics
Adrian R. Whyte, Sajida Rahman, Lynne Bell, Indika Edirisinghe, Robert Krikorian, Claire M. Williams, Britt Burton-Freeman
Summary: Research has shown that consuming wild blueberries can improve memory and executive function in middle-aged adults, reducing cognitive fatigue. Additionally, wild blueberries also improve post-meal glucose and insulin responses. Further investigation is needed to understand the underlying mechanisms of how wild blueberries enhance cognitive function.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Endocrinology & Metabolism
S. Abdelgani, C. Puckett, J. Adams, C. Triplitt, R. A. DeFronzo, M. Abdul-Ghani
Summary: The study demonstrated that beta cell function plays a vital role in predicting response to glucose lowering medications in newly diagnosed T2DM patients. The C-Pep(120)/C-Pep(0) ratio is a practical tool for guiding the choice of glucose lowering agent.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Mohamed Abu-Farha, Mariam Alatrach, Jehad Abubaker, Irina Al-Khairi, Preethi Cherian, Krisitn Agyin, Siham Abdelgani, Luke Norton, John Adams, Dalal Al-Saeed, Ebaa Al-Ozairi, Ralph A. DeFronzo, Fahd Al-Mulla, Muhammad Abdul-Ghani
Summary: It was found that the increase in plasma levels of ANGPTL8 is due to the increase in plasma insulin concentration following food ingestion, not the rise in plasma glucose.
DIABETES-METABOLISM RESEARCH AND REVIEWS
(2023)
Review
Endocrinology & Metabolism
Bo Ahren, Yuichiro Yamada, Yutaka Seino
Summary: The insulin response to oral glucose is influenced by incretin hormones such as GLP-1 and GIP. Studies on GIP and GLP-1 receptor knockout mice have shown varying results regarding glucose tolerance following oral glucose administration. Further investigations on mice with genetic deletions of both receptors suggest a potential dependence of incretin hormone relevance on glucose load, with GIP receptor KO mice exhibiting glucose intolerance after large glucose loads but not smaller ones, while GLP-1 receptor KO mice show normal glucose tolerance with an increased insulin response.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Sahar Foshati, Sajjad Moradi, Mohammad Tavassoly, Mohammad Hossein Rouhani
Summary: Both long-term and short-term capsaicin supplementation do not have significant effects on blood glucose and insulin levels. The dose and ingestion form of capsaicin may contribute to the heterogeneity between studies.
Article
Plant Sciences
Li Li, Shuang Dai, Jing-ya Liu, Wei Wu, Qian-xi Zhao, Xin Wang, Na Wang, Zhi-hong Xu
Summary: In this study, it was found that dauricine could serve as a glucagon receptor antagonist, which could interfere with the binding of glucagon receptor and glucagon, thereby inhibiting the increase of blood glucose.
JOURNAL OF NATURAL PRODUCTS
(2022)
Article
Anatomy & Morphology
Giulia Corda, Barbara Noli, Barbara Manconi, Carla Brancia, Manuela Pellegrini, Fabio Naro, Alessandra Olianas, Gian-Luca Ferri, Cristina Cocco
Summary: The study showed that TLQP-21 peptide may be released from islets under hyperglycemic conditions to enhance insulin secretion. C3a-R1 was localized in approximately 50% of TLQP-labeled islet cells, while gC1q-R was detected in around 25% of the cells.
Article
Pharmacology & Pharmacy
Niels Rode Kristensen, Henrik Agerso
Summary: Response-based dose individualization is a powerful method for precise dosing. However, it is underused in drug development, possibly due to data analysis challenges and selection bias risks. This study demonstrates through simulations that using a population approach can overcome the titration paradox and provide accurate dose/exposure-response modeling.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY
(2022)
Review
Chemistry, Applied
Haocun Kong, Luxi Yu, Caiming Li, Xiaofeng Ban, Zhengbiao Gu, Long Liu, Zhaofeng Li
Summary: Starch is an important carbohydrate in the human diet and is associated with human health. Besides glycemic response, studies have shown that glucose kinetics, insulin response, and gut hormones release play critical roles in determining the health effects of starch.
CARBOHYDRATE POLYMERS
(2022)
Article
Agriculture, Dairy & Animal Science
M. Duplessis, C. L. Girard
Summary: The study aimed to evaluate the glucose and insulin metabolism in cows with supplementation of biotin, folic acid, and vitamin B-12 during the transition period. Results showed that cows receiving a biotin supplement had reduced insulin sensitivity in early lactation, while cows supplemented with folic acid and vitamin B-12 had a faster insulin response, though this did not lead to further improvements after a glucose challenge.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Food Science & Technology
Fei Au-Yeung, Alexandra L. Jenkins, Steve Prancevic, Esther Vissers, Janice E. Campbell, Thomas M. S. Wolever
Summary: Allulose is a naturally occurring monosaccharide that is about 70% as sweet as sucrose, and consuming it with a carbohydrate-containing meal may help to reduce postprandial glucose levels. It is unclear whether a higher ratio of allulose to carbohydrates can further inhibit both glycemic and insulin responses.
JOURNAL OF FUNCTIONAL FOODS
(2023)