Article
Gastroenterology & Hepatology
Maria Ines Pinto-Sanchez, Andrea Nardelli, Rajka Borojevic, Giada De Palma, Natalia Causada Calo, Justin McCarville, Alberto Caminero, Daniel Basra, Alexa Mordhorst, Ekatherina Ignatova, Suzanne Hansen, Melanie Uhde, Gary L. Norman, Joseph A. Murray, Edgardo Smecuol, David Armstrong, Julio C. Bai, Detlef Schuppan, Stephen M. Collins, Armin Alaedini, Paul Moayyedi, Elena F. Verdu, Premysl Bercik
Summary: Patients with antigliadin IgG and IgA in IBS showed improvement in symptoms, particularly diarrhea, on a gluten-free diet. The presence of these antibodies was associated with overall reductions in symptoms, with improvements in pain and mental health. Larger studies are needed to validate these findings.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Nutrition & Dietetics
Joost P. Algera, Stine Storsrud, Annika Lindstrom, Magnus Simren, Hans Tornblom
Summary: This study found a significant variation in gluten intake among IBS patients, with those experiencing more severe GI symptoms consuming lower levels of gluten. There was no significant association observed between fructan intake and GI symptoms.
CLINICAL NUTRITION
(2021)
Review
Nutrition & Dietetics
Bara Aljada, Ahmed Zohni, Wael El-Matary
Summary: The gluten-free diet is popular for treating immune-mediated disorders caused by gluten, but it has disadvantages like high costs, nutritional deficiencies, and social and psychological barriers. Close follow-up with patients following the diet is recommended, and more data is needed to assess its effectiveness in managing mental and cognitive disorders.
Review
Medicine, General & Internal
A. Rej, A. Avery, I Aziz, C. J. Black, R. K. Bowyer, R. L. Buckle, L. Seamark, C. C. Shaw, J. Thompson, N. Trott, M. Williams, D. S. Sanders
Summary: There is a renewed interest in using dietary therapies to manage irritable bowel syndrome (IBS), with traditional dietary advice (TDA), gluten-free diet (GFD) and low FODMAP diet (LFD) being the main focus. Evidence shows that TDA is effective based on case control studies and clinical experience, while randomized controlled trials (RCT) have proven the benefits of soluble fiber in IBS. Short-term studies show the efficacy of GFD, but long-term outcomes are lacking. LFD has good evidence for short-term and long-term benefits. There is currently no evidence to suggest one diet is superior to another, but TDA is more acceptable to patients. Dietitians should assess dietary triggers and tailor interventions according to patient choice. Alternative approaches like group clinics and online webinars can improve accessibility for patients. Further research is needed to compare dietary therapies with other management strategies for IBS.
Review
Nutrition & Dietetics
Robin Spiller
Summary: IBS is strongly influenced by diet, but identifying specific food intolerances is difficult due to the complexities of diet. Rapidly fermented carbohydrates and gut-specific mast cell activation may cause symptoms in IBS patients. More research is needed to fully understand the mechanisms of food intolerances and improve personalized medicine approaches to diet in IBS.
Review
Medicine, General & Internal
Xingxing Wu, Lin Qian, Kexin Liu, Jing Wu, Zhaowei Shan
Summary: Coeliac disease is an autoimmune intestinal disease induced by gluten, and adherence to gluten-free diet is an effective treatment. The gut microbiota plays a crucial role in maintaining health, which is regulated by diet. There is a need for alternative treatments to GFD due to the increasing prevalence of coeliac disease.
ANNALS OF MEDICINE
(2021)
Review
Nutrition & Dietetics
Annamaria Altomare, Claudia Di Rosa, Elena Imperia, Sara Emerenziani, Michele Cicala, Michele Pier Luca Guarino
Summary: The study explores the effects of different nutritional protocols on IBS-D symptoms and intestinal microbiota variations. An ideal nutritional protocol does not yet exist for IBS-D patients, but it is crucial to consider the impact of different nutritional approaches on the composition of the intestinal microbiota for better management of this functional disorder.
Article
Genetics & Heredity
Yuhao Sun, Xuejie Chen, Shuyang Wang, Minzi Deng, Ying Xie, Xiaoyan Wang, Jie Chen, Therese Hesketh
Summary: This study utilized Mendelian randomization design to investigate the causal relationship between gluten intake and IBS, finding that a gluten-free diet might be a protective factor of IBS. The results were stable and consistent across different analyses, suggesting the importance of considering lower gluten intake in IBS prevention and clinical practice.
FRONTIERS IN GENETICS
(2021)
Article
Nutrition & Dietetics
Michele J. Alkalay
Summary: Lactose malabsorption, celiac disease, non-celiac gluten sensitivity, and irritable bowel syndrome are conditions associated with food triggers and can cause nutritional detriments. This review provides an overview of the complex nutritional elements of these disorders, which is critical for medical providers to recognize.
Article
Nutrition & Dietetics
Gloria Galli, Marilia Carabotti, Emanuela Pilozzi, Edith Lahner, Bruno Annibale, Laura Conti
Summary: The study found that approximately 36.3% of celiac disease patients continue to experience persistent gastrointestinal symptoms and/or malabsorption signs despite being on a gluten-free diet. This persistence is associated with a longer duration of symptoms before CD diagnosis (>= 5 years) and the presence of constipation at the time of CD diagnosis. Other variables, including age at CD diagnosis, sex, duration of GFD, comorbidities, CD serology positivity, and severity of duodenal damage, were not found to have an association with the persistence of symptoms/signs. The relationship between symptoms/signs and histological findings remains unclear in CD management.
Review
Nutrition & Dietetics
Aner Cardo, Itziar Churruca, Arrate Lasa, Virginia Navarro, Maialen Vazquez-Polo, Gesala Perez-Junkera, Idoia Larretxi
Summary: Celiac disease (CD) is an autoimmune disorder of the small intestine that requires a gluten-free diet (GFD) for effective treatment. Nutritional imbalances may occur in adults with CD following GFD, but deficiencies can improve as intestinal mucosa recovers over time. Monitoring nutrient intake, especially plant proteins and essential nutrients, is important to prevent nutritional deficiencies in the long term.
Article
Nutrition & Dietetics
Laura Prospero, Giuseppe Riezzo, Michele Linsalata, Antonella Orlando, Benedetta D'Attoma, Francesco Russo
Summary: The study shows that a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (LFD) improves both gastrointestinal symptoms and the psychological profile of patients with irritable bowel syndrome with diarrhea (IBS-D). The LFD also enhances intestinal barrier function and reduces inflammation levels.
Article
Nutrition & Dietetics
Vincenza Lombardo, Alice Scricciolo, Andrea Costantino, Luca Elli, Giorgia Legnani, Angel Cebolla, Luisa Doneda, Federica Mascaretti, Maurizio Vecchi, Leda Roncoroni
Summary: The aim of this study was to evaluate the clinical efficacy of urinary gluten immunogenic peptides (uGIP) in the follow-up of celiac disease (CD). The results showed that uGIP test can accurately assess the adherence to gluten-free diet and correlated significantly with duodenal biopsy results.
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Vittoria Terrigno, Florencia Carbone, Jan Tack, Michele Cicala, Michele Pier Luca Guarino
Summary: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. The exact cause of IBS is not fully understood, but it is believed to involve a combination of factors such as abnormal gut motility, inflammation, increased intestinal permeability, and sensitivity. Diet and gut microbiota have also been identified as important contributors to IBS. This review examines the effects of dietary components, functional foods, prebiotics, probiotics, and symbiotics on symptoms and gut microbiota in individuals with IBS-C.
Review
Nutrition & Dietetics
Aaron Lerner, Jozelio Freire de Carvalho, Anna Kotrova, Yehuda Shoenfeld
Summary: A gluten-free diet may serve as a novel therapeutic strategy for classical non-gluten-dependent autoimmune conditions, with symptom relief observed in most patients.
Article
Neurosciences
Julie Iven, Jessica R. Biesiekierski, Dongxing Zhao, Jan Tack, Lukas Van Oudenhove
Summary: The study found that intragastric infusion of fructose did not have a significant effect on emotional ratings but did impact brain activity. The endocrine responses to fructose were influenced by sad emotion, and ghrelin levels were higher in sad emotion.
NUTRITIONAL NEUROSCIENCE
(2022)
Article
Gastroenterology & Hepatology
Jie Wu, Imke Masuy, Jessica R. Biesiekierski, Heather E. Fitzke, Chinar Parikh, Laurel Schofield, Hafsa Shaikh, Anisha Bhagwanani, Qasim Aziz, Stuart A. Taylor, Jan Tack, Lukas Van Oudenhove
Summary: Fructans induce similar changes in small bowel motility and colon gas and volume in patients with irritable bowel syndrome (IBS) and healthy controls (HCs). Increased symptom responses to fructans in IBS are associated with altered brain responses in pain-related regions, indicating a dysregulation of the gut-brain axis in FODMAP-induced symptom generation in IBS.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Pharmacology & Pharmacy
Jessica R. Biesiekierski, Caroline J. Tuck
Summary: The low FODMAP diet has changed therapeutic guidelines for managing symptoms of irritable bowel syndrome, and it is being explored as a potential management approach in other conditions. More research is needed to fully understand the effects of the low FODMAP diet on symptoms, safety, and efficacy across different diseases.
CURRENT OPINION IN PHARMACOLOGY
(2022)
Article
Gastroenterology & Hepatology
Florencia Carbone, Karen Van den Houte, Linde Besard, Celine Tack, Joris Arts, Philip Caenepeel, Hubert Piessevaux, Alain Vandenberghe, Christophe Matthys, Jessica Biesiekierski, Luc Capiau, Steven Ceulemans, Olivier Gernay, Lydia Jones, Sophie Maes, Christian Peetermans, Willem Raat, Jeroen Stubbe, Rudy Van Boxstael, Olivia Vandeput, Sophie Van Steenbergen, Lukas Van Oudenhove, Tim Vanuytsel, Michael Jones, Jan Tack
Summary: This study investigated the effects of a FODMAP-lowering diet application versus a spasmolytic agent in improving symptoms of IBS in primary care. The results showed that the FODMAP-lowering diet application was superior to the spasmolytic agent in improving IBS symptoms, suggesting it should be considered as the first-line treatment for IBS in primary care.
Article
Nutrition & Dietetics
Sharon Croxford, Emma Stirling, Susan McLeod, Jessica Biesiekierski, Emily Murray, Ashley H. Ng, Andrea Bramley, Adrienne Forsyth
Summary: This study aimed to explore the perspectives of nutrition professionals on the employability skills, knowledge and skills required in the industry for nutrition graduates, in order to understand the gaps in undergraduate nutrition curriculum. The results indicated that in addition to evidence-based discipline knowledge, interpersonal communication skills, including writing and listening, were identified as key skills needed for the roles of nutrition professionals. Participants expected universities to develop curriculum that addresses these gaps.
NUTRITION & DIETETICS
(2022)
Review
Gastroenterology & Hepatology
Jessica R. Biesiekierski, Lauren P. Manning, Helen Burton Murray, Johan W. S. Vlaeyen, Brjann Ljotsson, Lukas Van Oudenhove
Summary: Despite the conceptual opposite approaches, both exclusion diets and exposure-based CBT have demonstrated efficacy in reducing IBS symptoms. Further research is needed to explore predictors, mechanisms, and moderators of treatment outcomes.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Letter
Gastroenterology & Hepatology
Jessica R. Biesiekierski, Jie Wu, Lukas Van Oudenhove
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Review
Gastroenterology & Hepatology
Caroline J. Tuck, Nessmah Sultan, Matilda Tonkovic, Jessica R. Biesiekierski
Summary: There is a high prevalence of disordered eating in patients with gastrointestinal conditions, particularly those with DGBI. Orthorexia, an obsessive focus on healthy eating, may be common in this patient group. Dietary modifications may contribute to orthorexia, and clinicians should consider screening for disordered eating before implementing restrictive diets.
NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Review
Gastroenterology & Hepatology
Nessmah Sultan, Jane E. Varney, Emma P. Halmos, Jessica R. Biesiekierski, Chu K. Yao, Jane G. Muir, Peter R. Gibson, Caroline J. Tuck
Summary: This review discusses the optimal use of the FODMAP diet in different cultures, emphasizing the essential role of dietitians in implementing and managing the diet effectively.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY
(2022)
Article
Public, Environmental & Occupational Health
Ashley H. Ng, Yasser ElGhattis, Jessica R. Biesiekierski, George Moschonis
Summary: This study found that an online intervention delivered through social media effectively improved food literacy and fruit and vegetable consumption in Australian adults. Participants showed improved food literacy and increased daily servings of fruits and vegetables. Therefore, social media holds potential for promoting healthier diets in adults.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2022)
Review
Behavioral Sciences
Luke Hassan, Lisa Newman, Russell Keast, Jessica Danaher, Jessica R. Biesiekierski
Summary: This systematic literature review investigated the acute effects of administering different bitter tasting compounds on circulating levels of selected GI hormones, subjective appetite, and energy intake in humans. The data on food intake and subjective appetite were inconsistent, with only motilin and ghrelin responsive to post-oral bitter administration.
Review
Sport Sciences
Isabel G. Martinez, Alice S. Mika, Jessica R. Biesiekierski, Ricardo J. S. Costa
Summary: This article systematically reviews the impact of repetitive exposure to nutrients before and/or during exercise on gastrointestinal integrity, function, and symptoms. The results suggest that repetitive carbohydrate feeding can reduce gut discomfort and improve carbohydrate malabsorption and exercise-related gastrointestinal symptoms.
Article
Gastroenterology & Hepatology
Zoe M. Cooke, Stephanie M. Resciniti, Bradley J. Wright, Matthew W. Hale, Chu K. Yao, Caroline J. Tuck, Jessica R. Biesiekierski
Summary: This study compared dietary factors, symptoms, quality of life, and salivary cortisol levels between dyspepsia participants and healthy controls. The findings showed that dyspepsia participants followed special diets more frequently and identified FODMAPs as a key dietary trigger. Dyspepsia participants had lower nutritional intake, higher prevalence of anxiety and depression, poorer quality of life, and more severe gastrointestinal symptoms.
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Editorial Material
Nutrition & Dietetics
Katherine M. Livingstone, Jessica R. Biesiekierski, Catherine P. Bondonno, Victoria M. Flood
Summary: Nutrition scientists are facing the challenge of providing sustainable and ethical food to the world population while maintaining health and supporting the environment. The Nutrition Society of Australia's Annual Scientific meeting focused on the environmental impact of food systems, promoting sustainable eating practices, and ensuring optimal nutrition to prevent and manage chronic diseases. Collaboration among consumers, scientists, industry, and government is vital for finding solutions to this complex issue.
PROCEEDINGS OF THE NUTRITION SOCIETY
(2023)
Article
Medicine, General & Internal
Lauren P. Manning, Caroline J. Tuck, Jessica R. Biesiekierski
Summary: This narrative review explores the lived experience of patients with irritable bowel syndrome (IBS), with a focus on dietary involvement and diet management. The study found that IBS patients often face a trial-and-error process to identify trigger foods, uncertainty in food choices, and reduced enjoyment of food. However, dietary modifications are accepted as an effective management strategy by both patients and healthcare professionals. Establishing a meaningful relationship with healthcare professionals can improve patient adherence, treatment success, and overall satisfaction.
AUSTRALIAN JOURNAL OF GENERAL PRACTICE
(2022)