Thymoquinone, A Bioactive Component of Black Caraway Seeds, Causes G1 Phase Cell Cycle Arrest and Apoptosis in Triple-Negative Breast Cancer Cells with Mutant p53

Emerging targeted therapies in triple-negative breast cancer

(2012) J. Crown et al.   ANNALS OF ONCOLOGY

NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to thymoquinone-induced apoptosis

(2012) Kimberly M. Sutton et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

P53 and its molecular basis to chemoresistance in breast cancer

(2012) Stian Knappskog et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Cathepsin D Primes Caspase-8 Activation by Multiple Intra-chain Proteolysis

(2012) Sébastien Conus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

JKA97, a Novel Benzylidene Analog of Harmine, Exerts Anti-Cancer Effects by Inducing G1 Arrest, Apoptosis, and p53-Independent Up-Regulation of p21

(2012) Xinyi Yang et al.   PLoS One

Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP

(2012) Arumugam Paramasivam et al.   TOXICOLOGY LETTERS

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Thymoquinone: Potential cure for inflammatory disorders and cancer

(2011) Chern Chiuh Woo et al.   BIOCHEMICAL PHARMACOLOGY

Radiosensitization in human breast carcinoma cells by thymoquinone: role of cell cycle and apoptosis

(2011) Reelma Velho‑Pereira et al.   CELL BIOLOGY INTERNATIONAL

Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma

(2011) Azhar R. Hussain et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation

(2011) Kaouther Kolli-Bouhafs et al.   INVESTIGATIONAL NEW DRUGS

Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl-XL expression

(2011) Gamal Badr et al.   Lipids in Health and Disease

Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis

(2011) Marjo Huovinen et al.   TOXICOLOGY IN VITRO

Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

(2010) Feng Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line

(2010) Makiko Shimizu et al.   CANCER LETTERS

Assessing Women at High Risk of Breast Cancer: A Review of Risk Assessment Models

(2010) E. Amir et al.   JNCI-Journal of the National Cancer Institute

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells

(2010) El-Shaimaa A. Arafa et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer

(2010) Sanjeev Banerjee et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling

(2009) Nahed El-Najjar et al.   APOPTOSIS

Antitumor Activity of Gemcitabine and Oxaliplatin Is Augmented by Thymoquinone in Pancreatic Cancer

(2009) Sanjeev Banerjee et al.   CANCER RESEARCH