Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus

Chromatin remodeling mediated by the FOXA1/A2 transcription factors activatesCFTRexpression in intestinal epithelial cells

(2014) Jenny L Kerschner et al.   Epigenetics

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Global view of enhancer-promoter interactome in human cells

(2014) B. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF and Cohesin: Linking Gene Regulatory Elements with Their Targets

(2013) Matthias Merkenschlager et al.   CELL

Characterization of a large human transgene following invasin-mediated delivery in a bacterial artificial chromosome

(2013) Austin E. Gillen et al.   CHROMOSOMA

Cohesin at active genes: a unifying theme for cohesin and gene expression from model organisms to humans

(2013) Dale Dorsett et al.   CURRENT OPINION IN CELL BIOLOGY

Cohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments

(2013) V. C. Seitan et al.   GENOME RESEARCH

Coordinate Regulation of the Gel-forming Mucin Genes at Chromosome 11p15.5

(2013) Nehal Gosalia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Immune Mediators Regulate CFTR Expression through a Bifunctional Airway-Selective Enhancer

(2013) Z. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

(2013) J. Zuin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional networks driving enhancer function in theCFTRgene

(2012) Jenny L. Kerschner et al.   BIOCHEMICAL JOURNAL

Perinuclear positioning of the inactive human cystic fibrosis gene depends on CTCF, A-type lamins and an active histone deacetylase

(2012) Joscha S. Muck et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Comprehensive Identification and Annotation of Cell Type-Specific and Ubiquitous CTCF-Binding Sites in the Human Genome

(2012) Hebing Chen et al.   PLoS One

A microRNA network regulates expression and biosynthesis of wild-type and  F508 mutant cystic fibrosis transmembrane conductance regulator

(2012) S. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesin: genomic insights into controlling gene transcription and development

(2011) Dale Dorsett   CURRENT OPINION IN GENETICS & DEVELOPMENT

Cohesin Mediates Chromatin Interactions That Regulate Mammalian β-globin Expression

(2011) Richard Chien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms controlling CFTR gene expression in the airway

(2011) Zhaolin Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locus

(2011) Y. J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

Charting histone modifications and the functional organization of mammalian genomes

(2010) Vicky W. Zhou et al.   NATURE REVIEWS GENETICS

Cell-type-specific long-range looping interactions identify distant regulatory elements of the CFTR gene

(2010) Nele Gheldof et al.   NUCLEIC ACIDS RESEARCH

Cell type specificity of chromatin organization mediated by CTCF and cohesin

(2010) Chunhui Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus

(2009) Suzana Hadjur et al.   NATURE

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

An insulator element 3′ to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells

(2009) Neil P. Blackledge et al.   NUCLEIC ACIDS RESEARCH

A wave of nascent transcription on activated human genes

(2009) Y. Wada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intronic enhancers coordinate epithelial-specific looping of the active CFTR locus

(2009) C. J. Ott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

(2008) S. Cuddapah et al.   GENOME RESEARCH

The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions

(2008) Parimal Majumder et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE

CTCF physically links cohesin to chromatin

(2008) E. D. Rubio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Insulator Binding Protein CTCF Positions 20 Nucleosomes around Its Binding Sites across the Human Genome

(2008) Yutao Fu et al.   PLoS Genetics