Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly

Phenotypic investigations of the depletion of EngA inEscherichia coliare consistent with a role in ribosome biogenesis

(2014) Amrita Bharat et al.   FEMS MICROBIOLOGY LETTERS

The ABC-F protein EttA gates ribosome entry into the translation elongation cycle

(2014) Grégory Boël et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

EttA regulates translation by binding the ribosomal E site and restricting ribosome-tRNA dynamics

(2014) Bo Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural and Functional Insights into the Mode of Action of a Universally Conserved Obg GTPase

(2014) Boya Feng et al.   PLOS BIOLOGY

Crippling the Essential GTPase Der Causes Dependence on Ribosomal Protein L9

(2013) A. Naganathan et al.   JOURNAL OF BACTERIOLOGY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit

(2013) N. Li et al.   NUCLEIC ACIDS RESEARCH

Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process

(2013) Qiang Guo et al.   NUCLEIC ACIDS RESEARCH

Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

(2012) Daniel Boehringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ppGpp: magic beyond RNA polymerase

(2012) Zachary D. Dalebroux et al.   NATURE REVIEWS MICROBIOLOGY

Functional Characterization of EngAMS, a P-Loop GTPase of Mycobacterium smegmatis

(2012) Nisheeth Agarwal et al.   PLoS One

Potassium Acts as a GTPase-Activating Element on Each Nucleotide-Binding Domain of the Essential Bacillus subtilis EngA

(2012) Anne-Emmanuelle Foucher et al.   PLoS One

Outcome of the First Electron Microscopy Validation Task Force Meeting

(2012) Richard Henderson et al.   STRUCTURE

Extended C-terminus and length of the linker connecting the G-domains are species-specific variations in the EngA family of GTPases

(2012) Sushil Kumar Tomar et al.   FEBS Open Bio

Assembly of Bacterial Ribosomes

(2011) Zahra Shajani et al.   Annual Review of Biochemistry

Structure-Function Relationships of the G Domain, a Canonical Switch Motif

(2011) Alfred Wittinghofer et al.   Annual Review of Biochemistry

A Bayesian View on Cryo-EM Structure Determination

(2011) Sjors H.W. Scheres   JOURNAL OF MOLECULAR BIOLOGY

The Universally Conserved Prokaryotic GTPases

(2011) N. Verstraeten et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Structural basis for the function of a small GTPase RsgA on the 30S ribosomal subunit maturation revealed by cryoelectron microscopy

(2011) Qiang Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression phenotypes suggest that Der participates in a specific, high affinity interaction with membranes

(2011) Ryan Lee et al.   PROTEIN EXPRESSION AND PURIFICATION

Interaction of an Essential Escherichia coli GTPase, Der, with the 50S Ribosome via the KH-Like Domain

(2010) J. Hwang et al.   JOURNAL OF BACTERIOLOGY

Thermodynamic Characterization of ppGpp Binding to EF-G or IF2 and of Initiator tRNA Binding to Free IF2 in the Presence of GDP, GTP, or ppGpp

(2010) Vladimir A. Mitkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

A Bacterial GAP-Like Protein, YihI, Regulating the GTPase of Der, an Essential GTP-Binding Protein in Escherichia coli

(2010) Jihwan Hwang et al.   JOURNAL OF MOLECULAR BIOLOGY

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Role of GTPases in Bacterial Ribosome Assembly

(2009) Robert A. Britton   Annual Review of Microbiology

SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs

(2009) Tanvir R Shaikh et al.   Nature Protocols

It takes two to tango: regulation of G proteins by dimerization

(2009) Raphael Gasper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct GDP/GTP bound states of the tandem G-domains of EngA regulate ribosome binding

(2009) Sushil Kumar Tomar et al.   NUCLEIC ACIDS RESEARCH

Powering through ribosome assembly

(2009) B. S. Strunk et al.   RNA

Structural Insight into Nascent Polypeptide Chain-Mediated Translational Stalling

(2009) B. Seidelt et al.   SCIENCE

RelA Functionally Suppresses the Growth Defect Caused by a Mutation in the G Domain of the Essential Der Protein

(2008) J. Hwang et al.   JOURNAL OF BACTERIOLOGY

Flexible Fitting of Atomic Structures into Electron Microscopy Maps Using Molecular Dynamics

(2008) Leonardo G. Trabuco et al.   STRUCTURE