The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids
出版年份 2014 全文链接
标题
The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids
作者
关键词
-
出版物
NUCLEIC ACIDS RESEARCH
Volume 42, Issue 7, Pages 4712-4722
出版商
Oxford University Press (OUP)
发表日期
2014-01-25
DOI
10.1093/nar/gkt1407
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation
- (2013) Yong-Jie Zhang et al. HUMAN MOLECULAR GENETICS
- The Truncated C-terminal RNA Recognition Motif of TDP-43 Protein Plays a Key Role in Forming Proteinaceous Aggregates
- (2013) Yi-Ting Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43
- (2013) Peter J Lukavsky et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TDP-43 and FUS RNA-binding Proteins Bind Distinct Sets of Cytoplasmic Messenger RNAs and Differently Regulate Their Post-transcriptional Fate in Motoneuron-like Cells
- (2012) Claudia Colombrita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43: gumming up neurons through protein–protein and protein–RNA interactions
- (2012) Emanuele Buratti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Identification of RNA bound to the TDP-43 ribonucleoprotein complex in the adult mouse brain
- (2012) Ramesh K. Narayanan et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- The role of ubiquitin–proteasome system in ageing
- (2011) Peter Löw GENERAL AND COMPARATIVE ENDOCRINOLOGY
- TDP-43-induced Death Is Associated with Altered Regulation of BIM and Bcl-xL and Attenuated by Caspase-mediated TDP-43 Cleavage
- (2011) Hiroaki Suzuki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UG Repeats/TDP-43 Interactions near 5′ Splice Sites Exert Unpredictable Effects on Splicing Modulation
- (2011) Monica Passoni et al. JOURNAL OF MOLECULAR BIOLOGY
- RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS
- (2011) Shangxi Xiao et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
- (2011) Fabienne C. Fiesel et al. NUCLEIC ACIDS RESEARCH
- A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop
- (2011) Stephen Martin-Tumasz et al. NUCLEIC ACIDS RESEARCH
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
- (2010) C. Lagier-Tourenne et al. HUMAN MOLECULAR GENETICS
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
- (2010) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: A spectrum of TDP-43 proteinopathies
- (2010) Felix Geser et al. NEUROPATHOLOGY
- Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration
- (2010) T. F. Gendron et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
- (2010) S.-C. Ling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 Dimerizes in Human Cells in Culture
- (2009) Yuki Shiina et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Structural insights into TDP-43 in nucleic-acid binding and domain interactions
- (2009) P.-H. Kuo et al. NUCLEIC ACIDS RESEARCH
- RNA recognition motifs: boring? Not quite
- (2008) Antoine Cléry et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- TDP-43: an emerging new player in neurodegenerative diseases
- (2008) I-Fan Wang et al. TRENDS IN MOLECULAR MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started