A 5′, 8-cyclo-2′-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β

The Androgen Receptor's CAG/Glutamine Tract in Mouse Models of Neurological Disease and Cancer

(2017) Andrew P. Lieberman et al.   JOURNAL OF ALZHEIMERS DISEASE

Mutagenicity and Genotoxicity of (5′S)-8,5′-Cyclo-2′-deoxyadenosine in Escherichia coli and Replication of (5′S)-8,5′-Cyclopurine-2′-deoxynucleosides in Vitro by DNA Polymerase IV, Exo-Free Klenow Fragment, and Dpo4

(2014) Varsha Pednekar et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion

(2014) Meng Xu et al.   NUCLEIC ACIDS RESEARCH

Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system

(2014) Konstantin Kropachev et al.   NUCLEIC ACIDS RESEARCH

Base Excision Repair of Chemotherapeutically-Induced Alkylated DNA Damage Predominantly Causes Contractions of Expanded GAA Repeats Associated with Friedreich's Ataxia

(2014) Yanhao Lai et al.   PLoS One

A problem solving approach for the diastereoselective synthesis of (5′S)- and (5′R)-5′,8-cyclopurine lesions

(2014) Chryssostomos Chatgilialoglu et al.   Organic Chemistry Frontiers

Flap Endonuclease 1

(2013) Lata Balakrishnan et al.   Annual Review of Biochemistry

Translesion Synthesis of 8,5′-Cyclopurine-2′-deoxynucleosides by DNA Polymerases η, ι, and ζ

(2013) Changjun You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Instability of CTG Repeats is Governed by the Position of a DNA Base Lesion through Base Excision Repair

(2013) Yanhao Lai et al.   PLoS One

The oxidative DNA lesions 8,5′-cyclopurines accumulate with aging in a tissue-specific manner

(2012) Jin Wang et al.   AGING CELL

The Nucleotide Sequence, DNA Damage Location, and Protein Stoichiometry Influence the Base Excision Repair Outcome at CAG/CTG Repeats

(2012) Agathi-Vasiliki Goula et al.   BIOCHEMISTRY

DNA Polymerase β Gap-Filling Translesion DNA Synthesis

(2012) Parvathi Chary et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Stability of N-Glycosidic Bond of (5′S)-8,5′-Cyclo-2′-deoxyguanosine

(2012) Rajat S. Das et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1

(2012) Meng Xu et al.   NUCLEIC ACIDS RESEARCH

New Insights into the Reaction Paths of Hydroxyl Radicals with 2′-Deoxyguanosine

(2011) Chryssostomos Chatgilialoglu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Purine 5′,8-cyclonucleoside lesions: chemistry and biology

(2011) Chryssostomos Chatgilialoglu et al.   CHEMICAL SOCIETY REVIEWS

In VitroGap-directed Translesion DNA Synthesis of an Abasic Site Involving Human DNA Polymerases ϵ, λ, and β

(2011) Giuseppe Villani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational trapping of Mismatch Recognition Complex MSH2/MSH3 on repair-resistant DNA loops

(2011) W. H. Lang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Friedreich's Ataxia (GAA)n•(TTC)n Repeats Strongly Stimulate Mitotic Crossovers in Saccharomyces cerevisae

(2011) Wei Tang et al.   PLoS Genetics

Base excision repair and design of small molecule inhibitors of human DNA polymerase β

(2010) Samuel H. Wilson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats

(2010) Aarthy C. Vallur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

Radiation-induced formation of purine 5′,8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen

(2010) Nourreddine Belmadoui et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

(2009) Kent S. Gates   CHEMICAL RESEARCH IN TOXICOLOGY

The Block of DNA Polymerase δ Strand Displacement Activity by an Abasic Site Can Be Rescued by the Concerted Action of DNA Polymerase β and Flap Endonuclease 1

(2009) Giovanni Maga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination between Polymerase β and FEN1 Can Modulate CAG Repeat Expansion

(2009) Yuan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA Polymerase β Substrate Specificity

(2009) William A. Beard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

8,5′-Cyclopurine-2′-deoxynucleosides in DNA: Mechanisms of formation, measurement, repair and biological effects

(2008) Pawel Jaruga et al.   DNA REPAIR

The 8,5′-cyclopurine-2′-deoxynucleosides: Candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair

(2008) P.J. Brooks   DNA REPAIR

Accumulation of (5′S)-8,5′-cyclo-2′-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice

(2008) Güldal Kirkali et al.   DNA REPAIR

Oxidative DNA damage in polymorphonuclear leukocytes of patients with familial Mediterranean fever

(2007) Güldal Kirkali et al.   FREE RADICAL BIOLOGY AND MEDICINE