Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function

Flap Endonuclease 1

(2013) Lata Balakrishnan et al.   Annual Review of Biochemistry

Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

(2013) Bartosz Szczesny et al.   PLoS One

Mitochondrial DNA damage and its consequences for mitochondrial gene expression

(2012) Susan D. Cline   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Oxidative genome damage and its repair: Implications in aging and neurodegenerative diseases

(2012) Muralidhar L. Hegde et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

(2011) Katalin Módis et al.   BIOCHEMICAL PHARMACOLOGY

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

(2011) Péter Bai et al.   Cell Metabolism

XRCC1 coordinates disparate responses and multiprotein repair complexes depending on the nature and context of the DNA damage

(2011) Audun Hanssen-Bauer et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Apoptosis Induced by Persistent Single-strand Breaks in Mitochondrial Genome

(2011) Anne W. Tann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly(ADP-ribose) Polymerase-1 Is a Nuclear Epigenetic Regulator of Mitochondrial DNA Repair and Transcription

(2011) A. Lapucci et al.   MOLECULAR PHARMACOLOGY

Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury

(2010) Bartosz Szczesny et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets

(2010) Raga Krishnakumar et al.   MOLECULAR CELL

Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate

(2010) C. E. Strom et al.   NUCLEIC ACIDS RESEARCH

Production and characterization of recombinant protein preparations of Endonuclease G-homologs from yeast, C. elegans and humans

(2010) Jana Kieper et al.   PROTEIN EXPRESSION AND PURIFICATION

Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells

(2009) Katalin Erdélyi et al.   FASEB JOURNAL

Poly(ADP-ribose) Catabolism Triggers AMP-dependent Mitochondrial Energy Failure

(2009) Laura Formentini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity

(2009) Marianna N. Rossi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intra-mitochondrial poly(ADP-ribosyl)ation: Potential role for alpha-ketoglutarate dehydrogenase

(2009) Eszter Pankotai et al.   MITOCHONDRION

Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis

(2008) Mansour Akbari et al.   DNA REPAIR

Long Patch Base Excision Repair in Mammalian Mitochondrial Genomes

(2008) Bartosz Szczesny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Removal of Oxidative DNA Damage via FEN1-Dependent Long-Patch Base Excision Repair in Human Cell Mitochondria

(2008) P. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

(2008) C. Godon et al.   NUCLEIC ACIDS RESEARCH

EXOG, a novel paralog of Endonuclease G in higher eukaryotes

(2008) Iwona A. Cymerman et al.   NUCLEIC ACIDS RESEARCH

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases

(2007) Paul et al.   Frontiers in Bioscience-Landmark