G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold

Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops

(2012) Maja Marušič et al.   NUCLEIC ACIDS RESEARCH

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer

(2011) Troels B. Jensen et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Selection of G-Quadruplex Folding Topology with LNA-Modified Human Telomeric Sequences in K+Solution

(2011) Devranjan Pradhan et al.   CHEMISTRY-A EUROPEAN JOURNAL

HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges

(2011) Vineeth Thachappilly Mukundan et al.   NUCLEIC ACIDS RESEARCH

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

(2010) Rakesh N. Veedu et al.   CHEMISTRY & BIODIVERSITY

Screening and Improvement of an Anti-VEGF DNA Aptamer

(2010) Yoshihiko Nonaka et al.   MOLECULES

Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids

(2010) Erik B. Pedersen et al.   NUCLEIC ACIDS RESEARCH

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

(2010) Anna Pasternak et al.   NUCLEIC ACIDS RESEARCH

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

Locked nucleic acid as a novel class of therapeutic agents

(2010) Rakesh N. Veedu et al.   RNA Biology

Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence

(2010) Vitaly Kuryavyi et al.   STRUCTURE

Solution Structure of a Locked Nucleic Acid Modified Quadruplex: Introducing the V4 Folding Topology

(2009) Jakob T. Nielsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability

(2009) Niels Langkjær et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The structures of quadruplex nucleic acids and their drug complexes

(2009) Stephen Neidle   CURRENT OPINION IN STRUCTURAL BIOLOGY

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

(2009) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

Effect of Locked-Nucleic Acid on a Biologically Active G-Quadruplex. A Structure-Activity Relationship of the Thrombin Aptamer

(2008) Laura Bonifacio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

(2008) Xiang-Jun Lu et al.   Nature Protocols

Structural polymorphism of intramolecular quadruplex of human telomeric DNA: effect of cations, quadruplex-binding drugs and flanking sequences

(2008) T. I. Gaynutdinov et al.   NUCLEIC ACIDS RESEARCH