The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members

Genomic and Biochemical Insights into the Specificity of ETS Transcription Factors

(2011) Peter C. Hollenhorst et al.   Annual Review of Biochemistry

The Coactivator activator CoAA regulates PEA3 group member transcriptional activity

(2011) Kathye Verreman et al.   BIOCHEMICAL JOURNAL

MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms

(2011) Muna Affara et al.   BMC GENOMICS

ERβ and PEA3 co-activate IL-8 expression and promote the invasion of breast cancer cells

(2011) Ying Chen et al.   CANCER BIOLOGY & THERAPY

The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex

(2011) Peter S. Brzovic et al.   MOLECULAR CELL

Structure and VP16 binding of the Mediator Med25 activator interaction domain

(2011) Erika Vojnic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the VP16 transactivator target in the Mediator

(2011) Alexander G Milbradt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF)

(2011) C. Mas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interactions between subunits of the Mediator complex with gene-specific transcription factors

(2011) Tilman Borggrefe et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mediator-dependent nuclear receptor function

(2011) Wei Chen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25

(2011) Yukio Nakamura et al.   Nature Communications

Solution structure of the N-terminal transactivation domain of ERM modified by SUMO-1

(2010) Zoé Lens et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Kaposi's sarcoma-associated herpesvirus Lana-1 is a major activator of the serum response element and mitogen-activated protein kinase pathways via interactions with the Mediator complex

(2010) M. Roupelieva et al.   JOURNAL OF GENERAL VIROLOGY

NMR structure of the human Mediator MED25 ACID domain

(2010) François Bontems et al.   JOURNAL OF STRUCTURAL BIOLOGY

Med25 Is Required for RNA Polymerase II Recruitment to Specific Promoters, Thus Regulating Xenobiotic and Lipid Metabolism in Human Liver

(2010) R. Rana et al.   MOLECULAR AND CELLULAR BIOLOGY

The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation

(2010) Sohail Malik et al.   NATURE REVIEWS GENETICS

p53 activates transcription by directing structural shifts in Mediator

(2010) Krista D Meyer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Analysis of the Varicella-Zoster Virus IE62 N-Terminal Acidic Transactivating Domain and Its Interaction with the Human Mediator Complex

(2009) S. Yamamoto et al.   JOURNAL OF VIROLOGY

Two Modes of Transcriptional Activation at Native Promoters by NF-κB p65

(2009) Dominic van Essen et al.   PLOS BIOLOGY

ERM transcription factor contains an inhibitory domain which functions in sumoylation-dependent manner

(2008) Cindy Degerny et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Varicella-Zoster Virus IE62 Protein Utilizes the Human Mediator Complex in Promoter Activation

(2008) M. Yang et al.   JOURNAL OF VIROLOGY

The AIB1 Oncogene Promotes Breast Cancer Metastasis by Activation of PEA3-Mediated Matrix Metalloproteinase 2 (MMP2) and MMP9 Expression

(2008) L. Qin et al.   MOLECULAR AND CELLULAR BIOLOGY

Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex

(2008) Henri-Marc Bourbon   NUCLEIC ACIDS RESEARCH