Distinct isoforms of the Drosophila Brd4 homologue are present at enhancers, promoters and insulator sites

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

Genome-wide phosphoacetylation of histone H3 atDrosophilaenhancers and promoters

(2012) Wendy A. Kellner et al.   GENOME RESEARCH

Drosophila CTCF tandemly aligns with other insulator proteins at the borders of H3K27me3 domains

(2012) K. Van Bortle et al.   GENOME RESEARCH

Bromodomain Protein Brd4 Associated with Acetylated Chromatin Is Important for Maintenance of Higher-order Chromatin Structure

(2012) Ranran Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BRD4 is an atypical kinase that phosphorylates Serine2 of the RNA Polymerase II carboxy-terminal domain

(2012) B. N. Devaiah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Two-pronged Binding with Bromodomain-containing Protein 4 Liberates Positive Transcription Elongation Factor b from Inactive Ribonucleoprotein Complexes

(2011) Sebastian Schröder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Chromatin Organization and Inducible Gene Expression by a Drosophila Insulator

(2011) Ashley M. Wood et al.   MOLECULAR CELL

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

(2011) Rui Zhao et al.   NATURE CELL BIOLOGY

Long Noncoding RNAs with Enhancer-like Function in Human Cells

(2010) Ulf Andersson Ørom et al.   CELL

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

14-3-3 Mediates Histone Cross-Talk during Transcription Elongation in Drosophila

(2010) Caline S. Karam et al.   PLoS Genetics

A Comprehensive Map of Insulator Elements for the Drosophila Genome

(2010) Nicolas Nègre et al.   PLoS Genetics

Histone Crosstalk between H3S10ph and H4K16ac Generates a Histone Code that Mediates Transcription Elongation

(2009) Alessio Zippo et al.   CELL

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

(2009) F. Tie et al.   DEVELOPMENT

Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells

(2009) Sungyoo Cho et al.   EMBO JOURNAL

Three subclasses of a Drosophila insulator show distinct and cell type-specific genomic distributions

(2009) A. M. Bushey et al.   GENES & DEVELOPMENT

Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution

(2009) Friederike Vollmuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails†‡

(2008) Ying Liu et al.   BIOCHEMISTRY

Drosophila female sterile (1) homeotic is a multifunctional transcriptional regulator that is modulated by Ras signaling

(2008) Brian L. Florence et al.   DEVELOPMENTAL DYNAMICS

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS