The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
出版年份 2012 全文链接
标题
The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
作者
关键词
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出版物
NUCLEIC ACIDS RESEARCH
Volume 41, Issue 1, Pages 277-287
出版商
Oxford University Press (OUP)
发表日期
2012-10-20
DOI
10.1093/nar/gks976
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- RNA Polymerase II Elongation Control
- (2012) Qiang Zhou et al. Annual Review of Biochemistry
- Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study
- (2012) JP Routy et al. HIV MEDICINE
- Bromodomain and Extra-terminal (BET) Bromodomain Inhibition Activate Transcription via Transient Release of Positive Transcription Elongation Factor b (P-TEFb) from 7SK Small Nuclear Ribonucleoprotein
- (2012) Koen Bartholomeeusen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- BET bromodomain inhibition as a novel strategy for reactivation of HIV-1
- (2012) Camellia Banerjee et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Ubiquitin Ligase Siah1 Controls ELL2 Stability and Formation of Super Elongation Complexes to Modulate Gene Transcription
- (2012) Min Liu et al. MOLECULAR CELL
- ELL facilitates RNA polymerase II pause site entry and release
- (2012) Jung S. Byun et al. Nature Communications
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- The Control of HIV Transcription: Keeping RNA Polymerase II on Track
- (2011) Melanie Ott et al. Cell Host & Microbe
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 Tat and Host AFF4 Recruit Two Transcription Elongation Factors into a Bifunctional Complex for Coordinated Activation of HIV-1 Transcription
- (2010) Nanhai He et al. MOLECULAR CELL
- HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP
- (2010) Bijan Sobhian et al. MOLECULAR CELL
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation
- (2010) Iván D'Orso et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit
- (2010) Jonathan Karn Current Opinion in HIV and AIDS
- Expression of Latent HIV Induced by the Potent HDAC Inhibitor Suberoylanilide Hydroxamic Acid
- (2009) Nancie M. Archin et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Control of Inducible Gene Expression by Signal-Dependent Transcriptional Elongation
- (2009) Diana C. Hargreaves et al. CELL
- Nonclinical Safety Assessment of the Histone Deacetylase Inhibitor Vorinostat
- (2009) Janet S. Kerr et al. INTERNATIONAL JOURNAL OF TOXICOLOGY
- Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
- (2009) Friederike Vollmuth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Challenge of Finding a Cure for HIV Infection
- (2009) D. D. Richman et al. SCIENCE
- PP2B and PP1 cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling
- (2008) R. Chen et al. GENES & DEVELOPMENT
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