Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering

Predicting protein structures with a multiplayer online game

(2010) Seth Cooper et al.   NATURE

Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs

(2010) Justin Ashworth et al.   NUCLEIC ACIDS RESEARCH

IDENTIFICATION OF CONSERVED FEATURES OF LAGLIDADG HOMING ENDONUCLEASES

(2010) ALEXANDER GRISHIN et al.   Journal of Bioinformatics and Computational Biology

Exploitation of binding energy for catalysis and design

(2009) Summer B. Thyme et al.   NATURE

Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

(2009) Hui Li et al.   NUCLEIC ACIDS RESEARCH

Assessment of the optimization of affinity and specificity at protein–DNA interfaces

(2009) Justin Ashworth et al.   NUCLEIC ACIDS RESEARCH

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

(2009) Sylvestre Grizot et al.   NUCLEIC ACIDS RESEARCH

Heritable targeted mutagenesis in maize using a designed endonuclease

(2009) Huirong Gao et al.   PLANT JOURNAL

Simultaneous prediction of protein folding and docking at high resolution

(2009) Rhiju Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macromolecular Modeling with Rosetta

(2008) Rhiju Das et al.   Annual Review of Biochemistry

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

(2008) Pilar Redondo et al.   NATURE