期刊
NUCLEIC ACIDS RESEARCH
卷 39, 期 -, 页码 W107-W111出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkr248
关键词
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资金
- Danish Strategic and Independent Research Councils, through committee for strategic growth technologies and research council for Technology and Production
- Danish Center for Scientific Computing
- Danish Strategic Research Council
The function of non-coding RNA genes largely depends on their secondary structure and the interaction with other molecules. Thus, an accurate prediction of secondary structure and RNA-RNA interaction is essential for the understanding of biological roles and pathways associated with a specific RNA gene. We present web servers to analyze multiple RNA sequences for common RNA structure and for RNA interaction sites. The web servers are based on the recent PET (Probabilistic Evolutionary and Thermodynamic) models PETfold and PETcofold, but add user friendly features ranging from a graphical layer to interactive usage of the predictors. Additionally, the web servers provide direct access to annotated RNA alignments, such as the Rfam 10.0 database and multiple alignments of 16 vertebrate genomes with human. The web servers are freely available at: http://rth.dk/resources/petfold/.
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