Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting

Recombineering, transfection, Western, IP and ChIP methods for protein tagging via gene targeting or BAC transgenesis

(2011) Helmut Hofemeister et al.   METHODS

Initial impact of the sequencing of the human genome

(2011) Eric S. Lander   NATURE

Mapping copy number variation by population-scale genome sequencing

(2011) Ryan E. Mills et al.   NATURE

A conditional knockout resource for the genome-wide study of mouse gene function

(2011) William C. Skarnes et al.   NATURE

The next phase in human genetics

(2011) Vikas Bansal et al.   NATURE BIOTECHNOLOGY

Single-stranded heteroduplex intermediates in λ Red homologous recombination

(2010) Marcello Maresca et al.   BMC MOLECULAR BIOLOGY

LINE-1 Retrotransposition Activity in Human Genomes

(2010) Christine R. Beck et al.   CELL

Natural Mutagenesis of Human Genomes by Endogenous Retrotransposons

(2010) Rebecca C. Iskow et al.   CELL

Modeling Disease in Human ESCs Using an Efficient BAC-Based Homologous Recombination System

(2010) Hoseok Song et al.   Cell Stem Cell

A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells

(2010) Christa Buecker et al.   Cell Stem Cell

Generation of Sheffield (Shef) human embryonic stem cell lines using a microdrop culture system

(2010) Behrouz Aflatoonian et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Isolation of Specific Clones from Nonarrayed BAC Libraries through Homologous Recombination

(2010) Mikhail Nefedov et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Whole-genome molecular haplotyping of single cells

(2010) H Christina Fan et al.   NATURE BIOTECHNOLOGY

Haplotype-resolved genome sequencing of a Gujarati Indian individual

(2010) Jacob O Kitzman et al.   NATURE BIOTECHNOLOGY

Mutation spectrum revealed by breakpoint sequencing of human germline CNVs

(2010) Donald F Conrad et al.   NATURE GENETICS

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples

(2010) Isaäc J Nijman et al.   NATURE METHODS

Target-enrichment strategies for next-generation sequencing

(2010) Lira Mamanova et al.   NATURE METHODS

Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer

(2010) Juliann Chmielecki et al.   NUCLEIC ACIDS RESEARCH

Human single-nucleotide polymorphisms alter p53 sequence-specific binding at gene regulatory elements

(2010) Omari J. Bandele et al.   NUCLEIC ACIDS RESEARCH

Variation in Transcription Factor Binding Among Humans

(2010) M. Kasowski et al.   SCIENCE

Diversity of Human Copy Number Variation and Multicopy Genes

(2010) Peter H. Sudmant et al.   SCIENCE

Genomic views of distant-acting enhancers

(2009) Axel Visel et al.   NATURE

Single-molecule sequencing of an individual human genome

(2009) Dmitry Pushkarev et al.   NATURE BIOTECHNOLOGY

Microdroplet-based PCR enrichment for large-scale targeted sequencing

(2009) Ryan Tewhey et al.   NATURE BIOTECHNOLOGY

Computational methods for discovering structural variation with next-generation sequencing

(2009) Paul Medvedev et al.   NATURE METHODS

Human genetic variation and its contribution to complex traits

(2009) Kelly A. Frazer et al.   NATURE REVIEWS GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

The complete genome of an individual by massively parallel DNA sequencing

(2008) David A. Wheeler et al.   NATURE

Mapping and sequencing of structural variation from eight human genomes

(2008) Jeffrey M. Kidd et al.   NATURE

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

(2008) Ina Poser et al.   NATURE METHODS