InTERTpreting telomerase structure and function

Telomerase biogenesis: The long road before getting to the end

(2014) Franck Gallardo et al.   RNA Biology

Functional interaction between telomere protein TPP1 and telomerase

(2010) A. J. Zaug et al.   GENES & DEVELOPMENT

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA

(2010) Meghan Mitchell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity

(2010) Mingyi Xie et al.   NUCLEIC ACIDS RESEARCH

Syndromes of Telomere Shortening

(2009) Mary Armanios   Annual Review of Genomics and Human Genetics

Telomeres and telomerase in cancer

(2009) S. E. Artandi et al.   CARCINOGENESIS

Conservation of telomere protein complexes: shuffling through evolution

(2009) Benjamin R. Linger et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

An RPA-Related Sequence-Specific DNA-Binding Subunit of Telomerase Holoenzyme Is Required for Elongation Processivity and Telomere Maintenance

(2009) Bosun Min et al.   MOLECULAR CELL

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization

(2009) David C. F. Sealey et al.   NUCLEIC ACIDS RESEARCH

Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo

(2009) Haley D. M. Wyatt et al.   PLoS One

A Spectrum of Severe Familial Liver Disorders Associate with Telomerase Mutations

(2009) Rodrigo T. Calado et al.   PLoS One

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

(2009) A. S. Venteicher et al.   SCIENCE

TINF2, a Component of the Shelterin Telomere Protection Complex, Is Mutated in Dyskeratosis Congenita

(2008) Sharon A. Savage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

DNA Polymerases as Therapeutic Targets†

(2008) Anthony J. Berdis   BIOCHEMISTRY

TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes

(2008) A. J. Walne et al.   BLOOD

ExogenousTERCalone can enhance proliferative potential, telomerase activity and telomere length in lymphocytes from dyskeratosis congenita patients

(2008) Michael Kirwan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

(2008) Andrew S. Venteicher et al.   CELL

C. elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins

(2008) Marcela Raices et al.   CELL

Disease-Associated Human Telomerase RNA Variants Show Loss of Function for Telomere Synthesis without Dominant-Negative Interference

(2008) T. M. Errington et al.   MOLECULAR AND CELLULAR BIOLOGY

Structure of the Tribolium castaneum telomerase catalytic subunit TERT

(2008) Andrew J. Gillis et al.   NATURE

Mutation in TERT separates processivity from anchor-site function

(2008) Arthur J Zaug et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiple DNA-binding sites in Tetrahymena telomerase

(2008) Sharon N. Finger et al.   NUCLEIC ACIDS RESEARCH

Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita

(2008) T. Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP

(2008) C. Trahan et al.   RNA

Murine leukemia virus reverse transcriptase: Structural comparison with HIV-1 reverse transcriptase

(2008) Marie L. Coté et al.   VIRUS RESEARCH

Telomerase and its potential for therapeutic intervention

(2007) P Phatak et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dyskeratosis Congenita: A historical perspective

(2007) Amanda J. Walne et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Telomere uncapping and alternative lengthening of telomeres

(2007) Anthony J. Cesare et al.   MECHANISMS OF AGEING AND DEVELOPMENT