Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

Flap Endonuclease 1 Mechanism Analysis Indicates Flap Base Binding Prior to Threading

(2010) Jason W. Gloor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation

(2009) April M Reed et al.   Future Oncology

The 3′-Flap Pocket of Human Flap Endonuclease 1 Is Critical for Substrate Binding and Catalysis

(2009) L. David Finger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase

(2009) Adam Yasgar et al.   Molecular BioSystems

Impairment of APE1 Function Enhances Cellular Sensitivity to Clinically Relevant Alkylators and Antimetabolites

(2009) D. R. McNeill et al.   MOLECULAR CANCER RESEARCH

Identification of phosphotyrosine mimetic inhibitors of human tyrosyl-DNA phosphodiesterase I by a novel AlphaScreen high-throughput assay

(2009) C. Marchand et al.   MOLECULAR CANCER THERAPEUTICS

Synthetic Lethality — A New Direction in Cancer-Drug Development

(2009) J. Dirk Iglehart et al.   NEW ENGLAND JOURNAL OF MEDICINE

A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases

(2009) Dorjbal Dorjsuren et al.   NUCLEIC ACIDS RESEARCH

Dna2 is a structure-specific nuclease, with affinity for 5′-flap intermediates

(2009) Jason A. Stewart et al.   NUCLEIC ACIDS RESEARCH

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

(2009) Anton Simeonov et al.   PLoS One

Specific synthetic lethal killing of RAD54B-deficient human colorectal cancer cells by FEN1 silencing

(2009) K. J. McManus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Robotic Platform for Quantitative High-Throughput Screening

(2008) Sam Michael et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Fluorescence Spectroscopic Profiling of Compound Libraries

(2008) Anton Simeonov et al.   JOURNAL OF MEDICINAL CHEMISTRY