期刊
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA
卷 24, 期 1, 页码 1-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.soc.2014.09.001
关键词
Hepatocellular carcinoma; Chronic liver disease; Cirrhosis; Hepatitis B; Hepatitis C; Incidence; Risk factors; Aflatoxin
Hepatocellular carcinoma (Hcc) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer is poor, and an understanding of this disease and its risk factors is crucial for screening at-risk individuals, early recognition, and timely diagnosis. Most HCCs arise in the background of chronic liver disease caused by hepatitis B virus, hepatitis C virus, and chronic excessive alcohol intake. These underlying causes are characterized by marked variations in geography, gender, and other well-documented risk factors, some of which are potentially preventable.
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