Article
Physics, Multidisciplinary
Jakob Soltau, Markus Osterhoff, Tim Salditt
Summary: This novel approach to x-ray microscopy combines a multilayer zone plate with an iterative phase retrieval scheme to achieve high resolution and quantitative phase contrast.
PHYSICAL REVIEW LETTERS
(2022)
Article
Optics
Dorian Bouchet, Jacob Seifert, Allard P. Mosk
Summary: This study presents a numerical framework to quantify the precision of estimating parameters from measured data using the Fisher information matrix as a benchmark for assessing CDI methods. By optimizing the Fisher information metric with deep learning libraries, the research identifies an optimal illumination scheme for minimizing estimation errors under specific experimental constraints, paving the way for efficient characterization of structured samples at the sub-wavelength scale.
Article
Optics
Erik Malm, Edwin Fohtung, Anders Mikkelsen
Summary: The study presents a generalized phase retrieval method for multi-wavelength data in coherent diffractive imaging experiments, with discussions on limitations related to the number of wavelengths through constraint ratio adaptation. The method's performance is investigated through numerical simulations considering source spectrum, sample geometry, and complexity level.
Article
Chemistry, Multidisciplinary
Zachary Barringer, Jie Jiang, Xiaowen Shi, Elijah Schold, Anastasios Pateras, S. Cipiccia, C. Rau, Jian Shi, Edwin Fohtung
Summary: The defects in V2O3 grown via a flux method were studied, revealing large flake-like particles with spiral growth characteristics and smaller particles without the characteristic screw dislocation of spiral growth. The identification and measurement of various defects were done using Bragg coherent diffractive imaging.
Article
Optics
Benedikt J. Daurer, Simone Sala, Max F. Hantke, Hemanth K. N. Reddy, Johan Bielecki, Zhou Shen, Carl Nettelblad, Martin Svenda, Tomas Ekeberg, Gabriella A. Carini, Philip Hart, Timur Osipov, Andrew Aquila, N. Duane Loh, Filipe R. N. C. Maia, Pierre Thibault
Summary: This study demonstrates high-resolution multiple-plane wavefront imaging of XFEL pulses using mixed-state ptychography, providing insights into experimental sources of instability and emphasizing the importance of local photon fluence correction for SPI experiments. The detailed characterization will aid in interpreting data from past and future SPI experiments, and contribute to further improvements in experimental design and reconstruction algorithms.
Article
Biophysics
Chengfei Guo, Shaowei Jiang, Liming Yang, Pengming Song, Azady Pirhanov, Ruihai Wang, Tianbo Wang, Xiaopeng Shao, Qian Wu, Yong Ku Cho, Guoan Zheng
Summary: This article introduces a new on-chip imaging strategy called Depth-Multiplexed Ptychographic Microscopy (DPM) for parallel high-speed imaging. DPM stacks multiple specimens in the axial direction and images the entire z-stack simultaneously, which is different from the traditional sequential imaging strategy. The author modifies a low-cost car mirror to control the incident angle of the laser beam and places a blood-coated image sensor underneath the stacked sample for diffraction pattern acquisition. The DPM approach enables parallel imaging of multiple specimens using a single detector and offers a solution for on-chip sensing and imaging with efficient sample handling.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Optics
Li Song, Edmund Y. Lam
Summary: This paper proposes a fast and robust phase retrieval method for masked CDI based on the alternating direction method of multipliers (ADMM), which incorporates prior knowledge of the mask using a plug-and-play ADMM approach. The method utilizes a regularizer based on the structure tensor and Harris corner detector and achieves comparable reconstruction results with less time compared to conventional phase retrieval methods. Experimental validation on real in situ CDI data demonstrates the method's efficiency and robustness, making it suitable for imaging dynamic objects.
PHOTONICS RESEARCH
(2022)
Article
Biochemical Research Methods
Thomas Kierspel, Alan Kadek, Perdita Barran, Bruno Bellina, Adi N. Bijedic, Maxim Brodmerkel, Jan Commandeur, Carl Caleman, Tomislav Damjanovic, Ibrahim Dawod, Emiliano De Santis, Alexandros Lekkas, Kristina Lorenzen, Luis Lopez Morillo, Thomas G. Mandl, Erik Marklund, Dimitris Papanastasiou, Lennart A. I. Ramakers, Lutz Schweikhard, Florian Simke, Anna Sinelnikova, Athanasios Smyrnakis, Nicusor Timneanu, Charlotte Uetrecht
Summary: MS SPIDOC is a novel sample delivery system for single particle imaging at X-ray Free-Electron Lasers. It can handle a wide range of biological samples and has been integrated into large-scale facility beamlines. The system uses nano-electrospray ionization and m/z filtering to prepare the samples before they are oriented in the interaction zone. The simulation package developed alongside this prototype is described, with a focus on ion trajectory simulations, protein orientation, and coherent diffractive imaging of norovirus capsids.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2023)
Article
Physics, Particles & Fields
Daniel Boer, Chalis Setyadi
Summary: This paper extends a previous GTMD model to improve the description of diffractive dijet production and includes exclusive coherent diffractive J/psi production data. The results show considerable tension between the data for these two types of processes concerning the t dependence within the context and assumptions of the gluon GTMD model. Data from EIC for photo- and electroproduction of protons and nuclei, as well as UPC data from LHC and RHIC, can help establish whether a common GTMD description is possible and provide predictions for the various experiments beyond the description in terms of GPDs.
EUROPEAN PHYSICAL JOURNAL C
(2023)
Article
Chemistry, Multidisciplinary
Gerard N. Hinsley, Cameron M. Kewish, Grant A. van Riessen
Summary: This work demonstrates by simulation that kilohertz synchrotron CDI is possible by making use of redundant information from static parts of the image field. Reconstruction ambiguities are strongly suppressed by applying a spatiotemporal constraint. Dynamics an order of magnitude faster can be reconstructed compared with conventional CDI.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2022)
Article
Optics
Dongyu Yang, Junhao Zhang, Ye Tao, Wenjin Lv, Shun Lu, Hao Chen, Wenhui Xu, Yishi Shi
Summary: Deep CDI is a physics-driven untrained learning method that can reconstruct complex scenes from a single diffraction pattern with high confidence and fast reconstruction of dynamic processes.
Article
Multidisciplinary Sciences
Allan S. Johnson, Jordi Valls Conesa, Luciana Vidas, Daniel Perez-Salinas, Christian M. Gunther, Bastian Pfau, Kent A. Hallman, Richard F. Haglund, Stefan Eisebitt, Simon Wall
Summary: Solid-state systems can host a variety of thermodynamic phases that are challenging to study on the nanoscale due to the coexistence of multiple phases. Coherent diffractive imaging spectroscopy (CDIS) enables nanometer-scale resolution hyperspectral imaging of vanadium oxide, extracting refractive indices of different phases from a single sample without evidence of correlation-driven phase transitions. CDIS allows quantitative full-field x-ray spectromicroscopy for studying phase separation in extreme sample environments.
Article
Optics
Byungjae Hwang, Taeseong Woo, Cheolwoo Ahn, Jung-Hoon Park
Summary: A new phase retrieval method is proposed and demonstrated for imaging through random media. While methods for recovering the Fourier amplitude through random distortions are well established, recovering the Fourier phase has been a more difficult problem and remains an active and important research area. The authors show that by ensemble averaging shift-corrected images, the Fourier phase of an object obscured by random distortions can be accurately retrieved up to the diffraction limit. The method is simple, fast, and does not require any optimization parameters or prior knowledge about the sample.
LASER & PHOTONICS REVIEWS
(2023)
Article
Nanoscience & Nanotechnology
Xiaoliang He, Xingchen Pan, Hua Tao, Cheng Liu, Jianqiang Zhu
Summary: A linear model for coherent diffractive imaging (CDI) is proposed, which provides a unique solution for complex samples without any approximation. The proposed method is valid for all CDI-related imaging methods and the relationship between the method and the convergence of iterative phase retrieval is discussed. This mathematical model allows for analyzing the underlying physics of CDI and predicting the accuracy and error in CDI applications.
Article
Optics
Yikang He, Yan Guo, Junyan Hu, Xianye Li, Yanyang Ma, Baoqing Sun
Summary: This article introduces a coherent diffractive QPI scheme based on single-pixel imaging structure and coherent modulation imaging. Phase imaging is achieved through a single-point detector and a reweighted amplitude flow phase retrieval algorithm. The non-interference modality simplifies the apparatus and improves system robustness. The proposed technique demonstrates QPI of digital binary and grayscale objects, as well as phase retrieval for real objects, showing potential applications in biomedical imaging, x-ray diffraction imaging, and three-dimensional profilometry.
Article
Physics, Applied
Alessandra Patera, Carolina Arboleda, Veronica Ferrero, Elisa Fiorina, Konstantins Jefimovs, Alessandro Lo Giudice, Felix Mas Milian, Paolo Mereu, Stefania Pallotta, Luciano Ramello, Alessandro Re, Lorenzo Visca, Piergiorgio Cerello
Summary: The 4D GRAPH-X project aims to develop a prototype of an x-ray grating-based phase-contrast imaging scanner in a laboratory setting, optimized for analyzing moving objects and potential biomedical applications. Wave field simulations are used to optimize the setup specifications and construct a high-resolution and high-sensitivity imaging system.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Jack Binns, Connie Darmanin, Cameron M. Kewish, Sachini Kadaoluwa Pathirannahalge, Peter Berntsen, Patrick L. R. Adams, Stefan Paporakis, Daniel Wells, Francisco Gian Roque, Brian Abbey, Gary Bryant, Charlotte E. Conn, Stephen T. Mudie, Adrian M. Hawley, Timothy M. Ryan, Tamar L. Greaves, Andrew Martin
Summary: Intensity-correlation measurements provide access to nanostructural information in a wide range of ordered and disordered materials, beyond traditional pair-correlation methods. This study develops the theory of preferred orientation in intensity-correlation techniques and connects it to the well-established theory of texture analysis. Experimental demonstrations show that even minor deviations from uniform orientation produce the strongest angular correlation signals when the number of crystalline domains in the beam is large.
Article
Instruments & Instrumentation
Michael W. M. Jones, Grant A. van Riessen, Nicholas W. Phillips, Christoph E. Schrank, Gerard N. Hinsley, Nader Afshar, Juliane Reinhardt, Martin D. de Jonge, Cameron M. Kewish
Summary: This paper presents the implementation of high-speed ptychography at the Australian Synchrotron, including a free-run data collection mode that eliminates dead time and optimizes scan time. The study demonstrates that free-run data collection is viable for fast and high-quality ptychography, achieving extremely high data acquisition rate and spatial resolution enhancement. By combining with fast-scanning X-ray fluorescence microscopy, these methods provide morphological context for elemental and chemical information, enabling unique scientific outcomes.
JOURNAL OF SYNCHROTRON RADIATION
(2022)
Article
Chemistry, Analytical
Casey L. Doolette, Daryl L. Howard, Nader Afshar, Cameron M. Kewish, David J. Paterson, Jianyin Huang, Stefan Wagner, Jakob Santner, Walter W. Wenzel, Tom Raimondo, Alexander T. De Vries Van Leeuwen, Lei Hou, Frederik van der Bom, Han Weng, Peter M. Kopittke, Enzo Lombi
Summary: Synchrotron-based X-ray fluorescence microscopy (XFM) analysis is a powerful technique for visualizing elemental distributions in various sample types. We developed a novel approach using two fluorescence detectors in tandem to acquire two sets of XFM data simultaneously, achieving high throughput and scanning large samples in XFM experiments.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Zhitian Shi, Konstantins Jefimovs, Antonino La Magna, Marco Stampanoni, Lucia Romano
Summary: By introducing metal electric field modulators, controlled tilted etching can be achieved by modifying the near sample surface potential, thereby changing the incident angle of ions and obtaining a tilted profile.
APPLIED SURFACE SCIENCE
(2022)
Article
Fisheries
An V. Vu, Lee J. Baumgartner, Martin Mallen-Cooper, Gregory S. Doran, Karin E. Limburg, Bronwyn M. Gillanders, Jason D. Thiem, Julia A. Howitt, Cameron M. Kewish, Juliane Reinhardt, Ian G. Cowx
Summary: Migration tactics vary among fish species, and maintaining diversity in migration strategies is important in managing large tropical rivers.
FISHERIES MANAGEMENT AND ECOLOGY
(2022)
Article
Fisheries
An V. Vu, Lee J. Baumgartner, Karin E. Limburg, Gregory S. Doran, Martin Mallen-Cooper, Bronwyn M. Gillanders, Jason D. Thiem, Julia A. Howitt, Cameron M. Kewish, Juliane Reinhardt, Ian G. Cowx
Summary: This study examined the migratory ecology of pangasiid catfish in the Mekong River and identified two anadromous species with diverse migration strategies. The findings suggest that these catfish can migrate up to 700 km to 1400 km from the sea for spawning.
FISHERIES RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Gerard N. Hinsley, Cameron M. Kewish, Grant A. van Riessen
Summary: This work demonstrates by simulation that kilohertz synchrotron CDI is possible by making use of redundant information from static parts of the image field. Reconstruction ambiguities are strongly suppressed by applying a spatiotemporal constraint. Dynamics an order of magnitude faster can be reconstructed compared with conventional CDI.
JOURNAL OF APPLIED CRYSTALLOGRAPHY
(2022)
Article
Instruments & Instrumentation
Daniel J. Wells, Peter Berntsen, Eugeniu Balaur, Cameron M. Kewish, Patrick Adams, Andrew Aquila, Jack Binns, Sebastien Boutet, Hayden Broomhall, Carl Caleman, Andrew Christofferson, Charlotte E. Conn, Caroline Dahlqvist, Leonie Flueckiger, Francisco Gian Roque, Tamar L. Greaves, Majid Hejazian, Mark Hunter, Marjan Hadian Jazi, H. Olof Jonsson, Sachini Kadaoluwa Pathirannahalage, Richard A. Kirian, Alex Kozlov, Ruslan P. Kurta, Hugh Marman, Derek Mendez, Andrew Morgan, Keith Nugent, Dominik Oberthuer, Harry Quiney, Juliane Reinhardt, Saumitra Saha, Jonas A. Sellberg, Raymond Sierra, Max Wiedorn, Brian Abbey, Andrew Martin, Connie Darmanin
Summary: Serial crystallography of membrane proteins often uses high-viscosity injectors to deliver crystals to the X-ray beam. However, the potential impact of the injection process on the structure of the carrier medium, lipidic cubic phase (LCP), is not well understood. This study investigates the influence of injectors on LCP structure by analyzing phase changes during continuous flow injection. The results suggest that reservoir pressure does not correlate with observed phase changes, and different phase behaviors are observed during vacuum and atmospheric pressure injections.
JOURNAL OF SYNCHROTRON RADIATION
(2022)
Article
Multidisciplinary Sciences
Ronan Smith, Fabio De Marco, Ludovic Broche, Marie-Christine Zdora, Nicholas W. Phillips, Richard Boardman, Pierre Thibault
Summary: X-ray directional dark-field imaging is a technique that can reveal small-scale structural properties of a sample that are invisible in conventional imaging systems. We present an algorithm to extract the directional dark-field signal from X-ray speckle-based imaging data and demonstrate its accuracy in detecting and quantifying fiber orientation in carbon fiber-reinforced polymer samples.
Article
Computer Science, Interdisciplinary Applications
M. Busse, S. Ferstl, M. A. Kimm, L. Hehn, K. Steiger, S. Allner, M. Mueller, E. Drecoll, T. Buerkner, M. Dierolf, B. Gleich, W. Weichert, F. Pfeiffer
Summary: This article introduces a laboratory-based X-ray method for precise micromorphologic investigation of tissue samples in three dimensions, with the advantages of versatility in multi-scale investigations and nondestructive imaging.
IEEE TRANSACTIONS ON MEDICAL IMAGING
(2022)
Article
Optics
Fabio De Marco, Sara Savatovi, Ronan Smith, Vittorio Di Trapani, Marco Margini, Ginevra Lautizi, Pierre Thibault
Summary: Wavefront-marking X-ray imaging techniques use intensity fluctuations generated by sandpaper or a grating to analyze their distortion caused by the sample, thereby retrieving attenuation, phase-contrast, and dark-field information. These techniques, including phase contrast and dark-field, have wide biomedical and engineering applications. The Unified Modulated Pattern Analysis (UMPA) model has been developed to extract these modalities from wavefront-marking data, and a new UMPA implementation is presented in this study with enhanced capabilities for processing large datasets and extending the field of view. Possible artifacts and additional new features are also discussed.
Article
Chemistry, Physical
Alberta Terzi, Nunzia Gallo, Teresa Sibillano, Davide Altamura, Annalia Masi, Rocco Lassandro, Alessandro Sannino, Luca Salvatore, Oliver Bunk, Cinzia Giannini, Liberato De Caro
Summary: Type I collagen scaffold is widely used in tissue engineering and medical applications. The hierarchical structure and multiscale integrity of collagen from different animal sources were studied in relation to tissue-specific regeneration and scaffold design. The structural organization of collagen in tendons was investigated using X-ray scattering techniques and thermal and load-bearing tests.
Letter
Oncology
Carlo Morasso, Renzo Vanna, Francesca Piccotti, Lidia Frizzi, Marta Truffi, Sara Albasini, Camelia Borca, Thomas Huthwelker, Laura Villani, Oliver Bunk, Cinzia Giannini, Fabio Corsi
CANCER COMMUNICATIONS
(2023)
Article
Geochemistry & Geophysics
Ismay Venice Akker, Christoph Schrank, Marco Herwegh, Alfons Berger, Michael Jones, Cameron M. Kewish
Summary: This study presents quantitative information on the distribution of calcite veins in the exhumed Infrahelvetic Flysch Units in the eastern central Alps in Switzerland and explores their interaction with seismic activity. The findings suggest that the vein systems could be related to low magnitude earthquakes or slow-slip events.
GEOCHEMISTRY GEOPHYSICS GEOSYSTEMS
(2023)
