期刊
NEW JOURNAL OF CHEMISTRY
卷 36, 期 9, 页码 1717-1720出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2nj40482f
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资金
- National Basic Research Program of China (973 Program) [2012CB933602]
- Research Fund for the Doctoral Program of Higher Education [20090074120009]
- Natural Science Foundation of China [51072053, 21001043]
- Fundamental Research Funds for the Central Universities [WD 1114004]
Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.
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