Efficient immobilization of fructose-6-phosphate aldolase in layered double hydroxide: improved stereoselective synthesis of sugar analogues

Fructose-6-phosphate aldolase immobilized on layered double hydroxide 9FSA@LDH) has been characterized and evaluated as a biocatalyst in aldol reactions. The versatile FSA@LDH showed a comparable activity to the free FSA and can be reused several times without a notable loss of activity.