Review
Radiology, Nuclear Medicine & Medical Imaging
A. J. Lainez Ramos-Bossini, D. Lopez Zuniga, F. Ruiz Santiago
Summary: Percutaneous vertebroplasty (PVP) is more effective than conservative treatment (CT) in treating osteoporotic vertebral fractures, with limited benefits compared to placebo. Short-term PVP provides faster pain relief, while medium and long-term results help improve quality of life.
EUROPEAN RADIOLOGY
(2021)
Article
Medicine, General & Internal
Marcello Covino, Raffaele Vitiello, Giuseppe De Matteis, Nicola Bonadia, Andrea Piccioni, Luigi Carbone, Raffaella Zaccaria, Michele Cauteruccio, Veronica Ojetti, Francesco Franceschi
Summary: This study aimed to evaluate the risk of fracture as a consequence of trauma and its association with kidney function status in a cohort of elderly patients. The results showed that patients with non-end stage chronic kidney disease (CKD) had an increased risk of femur fracture after a fall, which may be associated with increased bone fragility. Active osteoporosis therapy was found to be an effective preventive factor.
AMERICAN JOURNAL OF THE MEDICAL SCIENCES
(2022)
Review
Geriatrics & Gerontology
Abadi K. Gebre, Joshua R. Lewis, Kevin Leow, Pawel Szulc, David Scott, Peter R. Ebeling, Marc Sim, Germaine Wong, Wai H. Lim, John T. Schousboe, Douglas P. Kiel, Richard L. Prince, Alexander J. Rodriguez
Summary: Abdominal aortic calcification (AAC) is associated with lower bone mineral density (BMD) and increased fracture risk. Detecting AAC during BMD testing may provide guidance for diagnosing bone health and predicting fracture risk.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Endocrinology & Metabolism
Xing-Hao Yu, Yong-Yue Wei, Ping Zeng, Shu-Feng Lei
Summary: The study found consistent causal associations between birth weight and osteoporosis risk, with significant mediation effects of adult weight and height. Results revealed the impact of fetal origin phenotypes on outcomes in late adulthood and provided important clues for early prevention research on osteoporosis.
JOURNAL OF BONE AND MINERAL RESEARCH
(2021)
Article
Medicine, General & Internal
Carolyn J. Crandall, Rebecca P. Hunt, Andrea Z. LaCroix, John A. Robbins, Jean Wactawski-Wende, Karen C. Johnson, Maryam Sattari, Katie L. Stone, Julie C. Weitlauf, Tanya R. Gure, Jane A. Cauley
Summary: This study prospectively analyzed the association between subsequent fractures in postmenopausal women after initial fractures at different sites. The results showed that different types of initial fractures increased the risk of subsequent fractures of different types, and this risk was observed across all age groups of women.
Article
Endocrinology & Metabolism
Liu Gao, Chang Liu, Pan Hu, Na Wang, Xiaoxue Bao, Bin Wang, Ke Wang, Yukun Li, Peng Xue
Summary: The objective of this study was to analyze the quantitative association between advanced glycation end products (AGEs) and adjusted FRAX by rheumatoid arthritis (FRAX-RA) in postmenopausal type 2 diabetic (T2D) patients. The optimal cutoff value of AGEs was also explored, which was aimed at demonstrating the potential value of AGEs on evaluating osteoporotic fracture risk in postmenopausal T2D patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Food Science & Technology
Weili Feng, Xiaoping Wang, Daoqiang Huang, Anqi Lu
Summary: This study used an umbrella review and meta-analysis to summarize the association between dietary factors and the incidence of osteoporosis in adults. The findings suggest that dietary factors have an impact on osteoporosis, and consuming appropriate amounts of dairy products, vegetables, fruits, and micronutrients, while reducing alcohol and coffee intake, can help reduce the risk of osteoporosis.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Medicine, General & Internal
Sandra Kraljevic Pavelic, Dalibor Krpan, Marta Zuvic, Sandra Eisenwagen, Kresimir Pavelic
Summary: Osteoporosis is a common condition that affects the quality of life of patients. Current standard treatments are not sufficient, and new approaches are needed. This study found that PMA-zeolite has positive effects on bone strength and fracture risk in osteoporotic patients, suggesting it could be a new therapeutic option.
FRONTIERS IN MEDICINE
(2022)
Review
Food Science & Technology
Hoda Zahedi, Fatemeh Atayie, Faezeh Samii Kondrud, Arghavan Balali, Joseph Beyene, Noorollah Tahery, Masoomeh Asadi, Omid Sadeghi
Summary: A meta-analysis in 2017 summarized the association between abdominal obesity and hip fracture, but no study has examined the dose-response association. In this study, the association between abdominal obesity and different types of bone fractures was investigated through a systematic review and dose-response meta-analysis. The results showed a significant positive association between abdominal obesity and risk of vertebral fracture.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Endocrinology & Metabolism
Mawson Wang, Markus J. Seibel
Summary: The burden of osteoporosis and osteoporotic fractures will increase with an aging population. Untreated osteoporotic fractures lead to higher morbidity, mortality, and risk of subsequent fractures. However, many patients with osteoporotic fractures are not investigated or treated for osteoporosis, creating a care gap. Fracture Liaison Services (FLS) have been established to improve care and focus on identification, investigation, and treatment initiation. Case vignettes illustrate the approach to secondary fracture prevention at a hospital-based FLS.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Anthony Delbar, Arnaud Pflimlin, Isabelle Delabriere, Camille Ternynck, Christophe Chantelot, Francois Puisieux, Bernard Cortet, Julien Paccou
Summary: The study at Lille University Hospital assessed persistence with osteoporosis treatment in patients from the Fracture Liaison Service over a period of 1 year. The results showed a high persistence rate at 12 months but dropped at 24 months. Independent predictors of non-persistence included follow-up performed by a general practitioner and treatment with zoledronic acid.
Article
Medicine, General & Internal
Valeria Frighi, Margaret Smith, Tim M. Andrews, Lei Clifton, Gary S. Collins, Alice Fuller, Jan Roast, Tim A. Holt
Summary: The incidence of fractures in individuals with intellectual disabilities is higher and occurs at an earlier age. Prevention and management strategies, particularly for hip fractures, are urgently needed.
Review
Endocrinology & Metabolism
Sa Sa Gao, Yongfang Zhao
Summary: The study evaluated the effect of beta-carotene on osteoporosis and found that beta-carotene intake was not associated with the overall risk of osteoporosis, but showed a negative association in certain subgroups (such as males, females, and Asians). Additionally, beta-carotene intake was positively associated with bone mineral density. Therefore, beta-carotene may improve BMD and reduce the risk of osteoporosis and fracture.
OSTEOPOROSIS INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
M. K. Skjodt, M. T. Ernst, S. Khalid, C. Libanati, C. Cooper, A. Delmestri, K. H. Rubin, M. K. Javaid, D. Martinez-Laguna, E. Toth, D. Prieto-Alhambra, B. Abrahamsen
Summary: This study reveals a significant and persistent treatment gap in anti-osteoporosis treatment in patients aged 50 years and older who suffered major osteoporotic fractures in Denmark between 2005 and 2014, even with the inclusion of hospital-administered treatments. Strengthened post-fracture care organization and secondary fracture prevention are urgently needed.
OSTEOPOROSIS INTERNATIONAL
(2021)
Review
Nutrition & Dietetics
Ligia J. Dominguez, Nicola Veronese, Stefano Ciriminna, Jose Luis Perez-Albela, Vania Flora Vasquez-Lopez, Santiago Rodas-Regalado, Giovanna Di Bella, Angela Parisi, Federica Tagliaferri, Mario Barbagallo
Summary: This systematic review and meta-analysis aimed to investigate the impact of serum magnesium on the risk of fractures. Four papers with a total of 119,755 participants were included in the systematic review. The findings suggested that lower serum magnesium concentrations were associated with a significantly higher risk of incident fractures. Further research is needed to confirm these results in other populations and explore the potential role of serum magnesium in fracture prevention.
