Article
Psychology, Multidisciplinary
Amke M. G. van Tintelen, Sophie H. Bolt, Eline Dalmijn, Danielle E. M. C. Jansen
Summary: This study examines the long-term wellbeing of (former) teenage mothers in the Netherlands. The findings suggest that, overall, these mothers are doing well and satisfied with their lives. However, short-term mothers face challenges in terms of income and housing. Family support is crucial, while formal support from social workers or institutions is also important. Tailored interventions are recommended to address smoking among (former) teenage mothers.
JOURNAL OF REPRODUCTIVE AND INFANT PSYCHOLOGY
(2023)
Article
Pediatrics
Marie Camerota, Elisabeth C. McGowan, Judy Aschner, Annemarie Stroustrup, Margaret R. Karagas, Elisabeth Conradt, Sheila E. Crowell, Patricia A. Brennan, Brian S. Carter, Jennifer Check, Lynne M. Dansereau, Sheri A. DellaGrotta, Todd M. Everson, Jennifer B. Helderman, Julie A. Hofheimer, Jordan R. Kuiper, Cynthia M. Loncar, Carmen J. Marsit, Charles R. Neal, Thomas Michael O'Shea, Steven L. Pastyrnak, Stephen J. Sheinkopf, Lynne M. Smith, Xueying Zhang, Barry M. Lester
Summary: A multi-cohort study of preterm and term-born infants revealed two dysregulated neurobehavioral profiles with distinct perinatal antecedents. Factors such as gender, maternal age, and emotional state were predictive of neurobehavioral profiles. Further understanding of these factors could inform interventions for positive developmental outcomes.
PEDIATRIC RESEARCH
(2023)
Article
Engineering, Environmental
Zhenzhen Xie, Hong Liang, Maohua Miao, Ziliang Wang, Yao Chen, Lan Yang, Yan Zhou, Wencheng Cao, Wei Yuan
Summary: Prenatal exposure to PFASs is linked to increased attention problems in children, which can be mitigated by higher maternal nut intake.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Agartha Afful Boateng, Charles Owusu-Aduomi Botchwey, Bruce Afeti Adatorvor, Michael Afari Baidoo, Dorothy Serwaa Boakye, Richard Boateng
Summary: Recurrent teenage pregnancies in developing countries, including Ghana, are a public health issue that negatively affects the quality of life for teenage mothers, their children, and society as a whole. Factors influencing recurrent teenage pregnancies are found to be multifactorial, including peer pressure, parental neglect, poverty, living with a partner, and inadequate knowledge of family planning. Teenagers with recurrent pregnancies face financial difficulties and stigmatization in society.
Article
Obstetrics & Gynecology
Marcela C. Smid, Torri D. Metz, Gwen A. McMillin, Lisa Mele, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, John M. Thorp, George R. Saade, Alan T. N. Tita, Emily S. Miller, Dwight J. Rouse, Baha Sibai, Maged M. Costantine, Brian M. Mercer, Steve N. Caritis
Summary: This study examined the association between the presence of nicotine or cannabis metabolites in maternal urine and child neurodevelopmental outcomes. The results showed that prenatal nicotine or cannabis exposure was not associated with differences in IQ. However, cannabis exposure was associated with lower attention scores in early childhood. The study highlights the need for longitudinal studies to assess the association between prenatal nicotine and cannabis exposure and child neurodevelopmental outcomes, with a focus on timing and quantity of exposure.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Environmental Sciences
Lin Zhu, Yao Chen, Maohua Miao, Hong Liang, Jianya Xi, Yan Wang, Kaige Yang, Ziliang Wang, Wei Yuan
Summary: A Chinese cohort study found that moderate prenatal exposure to isoflavones is associated with decreased risks of childhood neurobehavioral problems, while high exposure is associated with increased risks. Moderate exposure to daidzein specifically has consistent neuroprotective effects on specific neurobehavioral problems, regardless of age and gender.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Public, Environmental & Occupational Health
Gabrielle Kang-Auger, Thuy Mai Luu, Nancy Low, Aimina Ayoub, Nathalie Auger
Summary: Prenatal cannabis use disorders may predict future childhood injuries from motor vehicle crashes, with the risk increasing with the child's age. Other drug use disorders during pregnancy were not associated with pediatric transport-related injuries.
PREVENTIVE MEDICINE
(2021)
Article
Psychiatry
Sandra P. Zoubovsky, Michael T. Williams, Sarah Hoseus, Shivani Tumukuntala, Amy Riesenberg, Jay Schulkin, Charles V. Vorhees, Kenneth Campbell, Hee-Woong Lim, Louis J. Muglia
Summary: Prenatal stress in mice leads to anxiety-like behavior and increased activity of the HPA axis. Evidence of fetal amygdala programming precedes these abnormalities. In adult offspring, there are sex-specific amygdalar transcriptional changes and dysfunction in neurotransmitter systems. These abnormalities are primarily driven by in-utero stress exposure, but postnatal maternal care changes can reverse anxiety-related behaviors and partially rescue gene alterations associated with neurotransmission.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Laure Nicolet, Amir Moayedoddin, Joel Djatche Miafo, Daniel Nzebou, Beat Stoll, Emilien Jeannot
Summary: The study found a high prevalence of depressive disorder symptoms among teenage or young pregnant women, estimated to be 70.0%. This risk is significantly increased by factors such as unintended pregnancy, being separated or single, experiencing depression and anxiety before childbirth, abortion experience, and domestic violence.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
K. K. Venkatesh, A. Leviton, R. N. Fichorova, R. M. Joseph, L. M. Douglass, J. A. Frazier, K. C. K. Kuban, H. P. Santos, R. C. Fry, T. M. O'Shea
Summary: Prenatal tobacco smoke exposure was associated with an increased risk of epilepsy at 10 years of age among children born extremely preterm, but not with other neurological impairments.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Immunology
Shameena Bake, Marisa R. Pinson, Sivani Pandey, Joanna P. Chambers, Roxanna Mota, Ashlyn E. Fairchild, Rajesh C. Miranda, Farida Sohrabji
Summary: The study shows that prenatal alcohol exposure can lead to neurobehavioral anomalies in adult offspring, with significant gender differences. Peripheral inflammation is associated with poor glucose metabolism and neurocognitive deficits in offspring, reduced spleen Treg numbers, increased circulating monocytes in male offspring, and suppressed cytokine levels in PAE males.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Pediatrics
Marie Camerota, Elisabeth C. McGowan, Brian S. Carter, Jennifer Check, Lynne M. Dansereau, Sheri A. DellaGrotta, Jennifer B. Helderman, Julie A. Hofheimer, Charles R. Neal, T. Michael O'Shea, Steven L. Pastyrnak, Lynne M. Smith, Barry M. Lester
Summary: This study found that prenatal risk phenotypes are associated with neurobehavioral impairment in children born very preterm. Infants born to mothers in the psychological risk group had increased risk of dysregulated neurobehavior at discharge and motor delay and externalizing problems at 24 months. Infants born to mothers in the physical risk group had increased risk of motor delay at 24 months.
JOURNAL OF PEDIATRICS
(2023)
Article
Medicine, General & Internal
Mihaela C. Radu, Loredana S. Manolescu, Razvan Chivu, Corneliu Zaharia, Calin Boeru, Melania-Elena Pop-Tudose, Andrei Necsulescu, Marina Otelea
Summary: This study aims to determine the characteristics of pregnant teenagers and the medical complications associated with pregnancy at a young age. The findings show that teenage pregnancy is associated with a low level of health literacy, a higher proportion of low-birth-weight babies, and shorter gestational age. Poverty and lack of education are also significant factors influencing teenage pregnancy.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2022)
Article
Obstetrics & Gynecology
Madelin E. Gardner, Amna Umer, Toni Rudisill, Brian Hendricks, Candice Lefeber, Collin John, Christa Lilly
Summary: Infants of teenage births are at increased risk of poor infant outcomes, and adequate prenatal care is crucial for their overall health. However, little is known about the association between inadequate prenatal care and poor infant outcomes in teenage populations, especially in rural areas.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Multidisciplinary Sciences
Nirav R. Shah, Kyung Mi Kim, Venus Wong, Eyal Cohen, Sarah Rosenbaum, Eli M. Cahan, Arnold Milstein, Henrik Toft Sorensen, Erzsebet Horvath-Puho
Summary: This study found that mothers of infants with major congenital anomalies had higher utilization of health care services, especially in outpatient, inpatient, surgical, and psychiatric services, compared to mothers of children without anomalies.
Article
Neurosciences
Jennifer A. Willford, Lidush Goldschmidt, Natacha M. De Genna, Nancy L. Day, Gale A. Richardson
Summary: As more Americans use marijuana, concerns over its long-term impact on cognitive functioning, particularly memory, have risen. Research shows mixed results on the effects of marijuana on memory, with early initiation of marijuana use before age 15 posing a greater risk of memory deficits in young adults. Prenatal marijuana exposure and early initiation of marijuana use were found to have long-term effects on memory function in adulthood.
NEUROTOXICOLOGY AND TERATOLOGY
(2021)
Article
Neurosciences
Natacha M. De Genna, Lidush Goldschmidt, Gale A. Richardson
Summary: This study examines the long-term effects of prenatal cocaine exposure (PCE) on adult sexual behavior. The results show an indirect pathway from PCE to sex under the influence of alcohol or drugs, but no direct effects on risky adult sexual behavior or STI risk.
NEUROTOXICOLOGY AND TERATOLOGY
(2022)
Article
Behavioral Sciences
Natacha M. De Genna, Jennifer A. Willford, Gale A. Richardson
Summary: With the increasing use of cannabis during pregnancy, it is important to understand the developmental effects of prenatal cannabis exposure (PCE). This review discusses methodological considerations and reviews findings from studies on PCE. The results suggest that PCE may have effects on birth weight but not long-term growth. It also has subtle yet enduring effects on memory and achievement, as well as consistent effects on externalizing behaviors that persist into adulthood.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
(2022)
Article
Public, Environmental & Occupational Health
Ashley Hill, Dara D. Mendez, Catherine L. Haggerty, Elizabeth Miller, Natacha M. De Genna
Summary: This study identified perinatal syndemic factors and examined their relationship with STI. The findings indicate evidence of a syndemic related to increased STI.
MATERNAL AND CHILD HEALTH JOURNAL
(2022)
Article
Public, Environmental & Occupational Health
Natacha M. De Genna, Lisa J. Germeroth, Maria Tina Benno, Bang Wang, Michele D. Levine
Summary: In non-pregnant populations, cannabis use and cannabis use disorder have been linked to tobacco use and less successful quit attempts. Results suggest that a history of CUD does not confer additional risk for perinatal cigarette use.
MATERNAL AND CHILD HEALTH JOURNAL
(2022)
Article
Psychology, Clinical
Natacha M. De Genna, Lidush Goldschmidt, Gale A. Richardson, Nancy L. Day
Summary: This study modeled maternal patterns of cannabis use over a long period of time and found that different patterns of maternal cannabis use predicted offspring substance use at age 22. Offspring of chronic cannabis users were more likely to use cannabis and develop cannabis use disorder, as well as be nicotine dependent at age 22.
ADDICTIVE BEHAVIORS
(2022)
Article
Neurosciences
Natacha M. De Genna, Stefanie Kennon-McGill, Lidush Goldschmidt, Gale A. Richardson, Judy C. Chang
Summary: One in four Americans have used cannabidiol (CBD) products in the past year. CBD use has become prevalent in many Western countries due to recent deregulation. Preclinical work has shown potential risks of CBD exposure during pregnancy. This study examined CBD use among pregnant individuals under the age of 22, and found that although a small number reported CBD use during pregnancy, a significant portion had tried these products. Further research is needed to investigate the effects of CBD on fetal development and infant outcomes.
NEUROTOXICOLOGY AND TERATOLOGY
(2023)
Meeting Abstract
Neurosciences
Natacha De Genna, Lidush Goldschmidt, Judy Chang, Gale Richardson
NEUROTOXICOLOGY AND TERATOLOGY
(2023)
Article
Neurosciences
Lidush Goldschmidt, Gale A. Richardson, Nancy L. Day, Natacha M. De Genna
Summary: This study examined factors associated with transitions from adolescence to young adulthood in relation to marijuana use. Prenatal exposures to alcohol and marijuana, as well as peers' marijuana use, delinquency, care-givers' financial strain, and race, were identified as key factors distinguishing different patterns of marijuana use change.
NEUROTOXICOLOGY AND TERATOLOGY
(2023)
Article
Obstetrics & Gynecology
Megana Dwarakanath, Fahmida Hossain, Phoebe Balascio, Mikaela C. Moore, Ashley V. Hill, Natacha M. De Genna
Summary: The objective of this study is to qualitatively examine coping mechanisms and desired supports in pregnant and birthing Black and Biracial adolescent and young adult women during the COVID-19 pandemic.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Public, Environmental & Occupational Health
Natacha M. De Genna, Robert W. S. Coulter, Lidush Goldschmidt, Nicole Boss, Fahmida Hossain, Gale A. Richardson
Summary: Sexual minority (SM) youth have higher rates of substance use and pregnancy. This study examines the impact of SM identity and syndemic factors on prenatal substance use among 14- to 21-year-olds. The results indicate that pregnant SM participants, primarily bisexual, were more likely to use tobacco and illicit drugs than heterosexual participants, and the association between SM identity and prenatal tobacco use was not influenced by syndemic factors, prenatal cannabis use, or household tobacco use.
Article
Developmental Biology
Natacha M. De Genna, Fahmida Hossain, Megana Dwarakanath, Phoebe Ms. Balascio, Mikaela Ms. Moore, Ashley V. Hill
Summary: This qualitative study focuses on the experiences of younger Black and Biracial pregnant and birthing people during the COVID-19 pandemic. The study found that pandemic-related stressors, lack of support, and vaccine hesitancy were the main concerns for these individuals, including mistrust in the government and experiences of racism in reproductive healthcare. Provider appeals that highlighted patient autonomy and science were more effective in encouraging vaccine uptake.
BIRTH DEFECTS RESEARCH
(2023)
Article
Substance Abuse
Natacha M. De Genna, Yang Qu, Yu Cheng, Rebecca L. Emery Tavernier, Rachel P. Kolko Conlon, Michele D. Levine
Summary: This study followed up with people who quit smoking during pregnancy and found that the first 3 months postpartum were a critical period for relapse. It also found that individuals with more prior quit attempts and higher smoking quantity before quitting were more likely to relapse within 90 days after delivery.
NICOTINE & TOBACCO RESEARCH
(2023)
Meeting Abstract
Developmental Biology
N. M. De Genna, G. A. Richardson
BIRTH DEFECTS RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Rachael K. Richter, Jocelyn C. Anderson, Elizabeth Miller, Amy E. Bonomi, Natacha M. De Genna, Zoe Feinstein, Gabriel Kass, Kelli Lampe, Abigail Mathier, Carla D. Chugani
Summary: The study highlights the elevated risk of sexual violence for students with disabilities. It emphasizes the importance of campus service use for this group, while also suggesting key intervention points for increasing accessibility, reducing stigma, and improving student experiences.
QUALITATIVE HEALTH RESEARCH
(2021)
