Melatonin Antagonizes Mn-Induced Oxidative Injury Through the Activation of Keap1–Nrf2–ARE Signaling Pathway in the Striatum of Mice

Upregulation of mitochondrial protease HtrA2/Omi contributes to manganese-induced neuronal apoptosis in rat brain striatum

(2014) J.K. Jiang et al.   NEUROSCIENCE

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

(2013) Fabiano M. Cordova et al.   ARCHIVES OF TOXICOLOGY

The Nrf2/SKN-1-dependent glutathione S-transferase π homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism

(2013) Raja Settivari et al.   NEUROTOXICOLOGY

Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway

(2013) Ulkan Kilic et al.   Nutrition & Metabolism

Oxidative stress involvement in manganese-induced alpha-synuclein oligomerization in organotypic brain slice cultures

(2013) Bin Xu et al.   TOXICOLOGY

Melatonin activates the Nrf2-ARE pathway when it protects against early brain injury in a subarachnoid hemorrhage model

(2012) Zhong Wang et al.   JOURNAL OF PINEAL RESEARCH

Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

(2012) Sadagopan Magesh et al.   MEDICINAL RESEARCH REVIEWS

Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury

(2012) Marcelo Farina et al.   NEUROCHEMISTRY INTERNATIONAL

Exogenous melatonin modulates apoptosis in the mouse brain induced by high-LET carbon ion irradiation

(2011) Yang Liu et al.   JOURNAL OF PINEAL RESEARCH

Role of manganese in neurodegenerative diseases

(2011) Aaron B. Bowman et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury

(2011) Dejan Milatovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Functional neurotoxicity of Mn-containing nanoparticles in rats

(2010) Gábor Oszlánczi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Low-Level Arsenic Impairs Glucose-Stimulated Insulin Secretion in Pancreatic Beta Cells: Involvement of Cellular Adaptive Response to Oxidative Stress

(2010) Jingqi Fu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats

(2010) Kyung Hee Jung et al.   JOURNAL OF PINEAL RESEARCH

Preweaning Mn exposure leads to prolonged astrocyte activation and lasting effects on the dopaminergic system in adult male rats

(2010) Cynthia H. Kern et al.   SYNAPSE

The protective effect of riluzole on manganese caused disruption of glutamate–glutamine cycle in rats

(2009) Yu Deng et al.   BRAIN RESEARCH

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model

(2009) Kyung Hee Jung et al.   JOURNAL OF PINEAL RESEARCH

Estrogen and Tamoxifen Protect against Mn-Induced Toxicity in Rat Cortical Primary Cultures of Neurons and Astrocytes

(2009) Eun-Sook Y. Lee et al.   TOXICOLOGICAL SCIENCES

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages

(2009) Courtney G. Woods et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Molecular mechanism of manganese exposure-induced dopaminergic toxicity

(2008) K. Prabhakaran et al.   BRAIN RESEARCH BULLETIN

In vitro effect of manganese chloride exposure on energy metabolism and oxidative damage of mitochondria isolated from rat brain

(2008) Fanglin Zhang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL

Melatonin reduces the neuronal loss, downregulation of dopamine transporter, and upregulation of D2 receptor in rotenone-induced parkinsonian rats

(2007) Chun-Hung Lin et al.   JOURNAL OF PINEAL RESEARCH