Modulating Microglia Activity with PPAR-γ Agonists: A Promising Therapy for Parkinson’s Disease?
出版年份 2012 全文链接
标题
Modulating Microglia Activity with PPAR-γ Agonists: A Promising Therapy for Parkinson’s Disease?
作者
关键词
PPAR-γ, Neuroinflammation, Neuroprotection, Parkinson’s disease, Cytokines
出版物
NEUROTOXICITY RESEARCH
Volume 23, Issue 2, Pages 112-123
出版商
Springer Nature
发表日期
2012-08-06
DOI
10.1007/s12640-012-9342-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inflammation and Adaptive Immunity in Parkinson's Disease
- (2013) R. L. Mosley et al. Cold Spring Harbor Perspectives in Medicine
- Methylphenidate Exposure Induces Dopamine Neuron Loss and Activation of Microglia in the Basal Ganglia of Mice
- (2012) Shankar Sadasivan et al. PLoS One
- Mitochondria and Programmed Cell Death in Parkinson's Disease: Apoptosis and Beyond
- (2011) Celine Perier et al. ANTIOXIDANTS & REDOX SIGNALING
- PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
- (2011) Tamas Varga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Rosiglitazone Does Not Improve Cognition or Global Function when Used as Adjunctive Therapy to AChE Inhibitors in Mild-to-Moderate Alzheimers Disease: Two Phase 3 Studies
- (2011) C. Harrington et al. Current Alzheimer Research
- The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
- (2011) Christine R Swanson et al. Journal of Neuroinflammation
- Docosahexaenoic acid modulates inflammatory and antineurogenic functions of activated microglial cells
- (2011) Maria Antonietta Ajmone-Cat et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA
- (2011) Noelia Granado et al. NEUROBIOLOGY OF DISEASE
- Dopamine D1 receptor deletion strongly reduces neurotoxic effects of methamphetamine
- (2011) S. Ares-Santos et al. NEUROBIOLOGY OF DISEASE
- Is the answer for Parkinson disease already in the medicine cabinet?: Unfortunately not
- (2011) J. H. Bower et al. NEUROLOGY
- Rosiglitazone decreases peroxisome proliferator receptor-gamma levels in microglia and inhibits TNF-alpha production: new evidences on neuroprotection in a progressive Parkinson's disease model
- (2011) A.R. Carta et al. NEUROSCIENCE
- Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson's and Alzheimer's Diseases as Disease Modifying Agents
- (2011) Moussa B. H. Youdim Experimental Neurobiology
- Oxidative Stress in Parkinson's Disease
- (2010) Chun Zhou et al. Annals of the New York Academy of Sciences
- Peroxisome proliferator-activated receptor gamma agonists as neuroprotective agents
- (2010) R.K. Kaundal et al. DRUG NEWS & PERSPECTIVES
- Toward a functional characterization of blood monocytes
- (2010) Prakash Saha et al. IMMUNOLOGY AND CELL BIOLOGY
- Future directions for immune modulation in neurodegenerative disorders: focus on Parkinson’s disease
- (2010) Kathleen A. Maguire-Zeiss et al. JOURNAL OF NEURAL TRANSMISSION
- Interleukin-1β contributes to dopaminergic neuronal death induced by lipopolysaccharide-stimulated rat glia in vitro
- (2010) Caitríona M. Long-Smith et al. JOURNAL OF NEUROIMMUNOLOGY
- THE ROLE OF TUMOR NECROSIS FACTOR-ALPHA IN COGNITIVE IMPROVEMENT AFTER PEROXISOME PROLIFERATOR-ACTIVATOR RECEPTOR GAMMA AGONIST PIOGLITAZONE TREATMENT IN ALZHEIMER'S DISEASE
- (2010) Haruo Hanyu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Anti-apoptotic Actions of PPAR-γ Against Ischemic Stroke
- (2010) Wen-Hsuan Fong et al. MOLECULAR NEUROBIOLOGY
- The myeloid cells of the central nervous system parenchyma
- (2010) Richard M. Ransohoff et al. NATURE
- Microglia in neurodegenerative disease
- (2010) V. Hugh Perry et al. Nature Reviews Neurology
- Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants
- (2010) Cintia Roodveldt et al. PLoS One
- Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
- (2010) F. Ginhoux et al. SCIENCE
- PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease
- (2010) B. Zheng et al. Science Translational Medicine
- Microglial Physiology: Unique Stimuli, Specialized Responses
- (2009) Richard M. Ransohoff et al. Annual Review of Immunology
- Innate and Adaptive Immunity for the Pathobiology of Parkinson's Disease
- (2009) David K. Stone et al. ANTIOXIDANTS & REDOX SIGNALING
- PPARγ agonist pioglitazone reduces matrix metalloproteinase-9 activity and neuronal damage after focal cerebral ischemia
- (2009) Seong-Ryong Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
- (2009) Kaoru Saijo et al. CELL
- Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice
- (2009) S. Fujisaka et al. DIABETES
- Unbalanced M1/M2 Phenotype of Peripheral Blood Monocytes in Obese Diabetic Patients: Effect of pioglitazone
- (2009) N. Satoh et al. DIABETES CARE
- PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson’s disease
- (2009) Nicoletta Schintu et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Nitrated -Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets
- (2009) A. D. Reynolds et al. JOURNAL OF IMMUNOLOGY
- Interleukin-10 provides direct trophic support to neurons
- (2009) Zhigang Zhou et al. JOURNAL OF NEUROCHEMISTRY
- Increased serum levels of soluble tumor necrosis factor-α receptor-1 in patients with Parkinson's disease
- (2009) Paula Scalzo et al. JOURNAL OF NEUROIMMUNOLOGY
- Protective Effects of Pioglitazone Against Global Cerebral Ischemic-Reperfusion Injury in Gerbils
- (2009) Ravinder K. Kaundal et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS
- (2009) Haruo Hanyu et al. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
- Neuroinflammation in Parkinson's disease: a target for neuroprotection?
- (2009) Etienne C Hirsch et al. LANCET NEUROLOGY
- Chronic expression of low levels of tumor necrosis factor-α in the substantia nigra elicits progressive neurodegeneration, delayed motor symptoms and microglia/macrophage activation
- (2009) Ana Laura De Lella Ezcurra et al. NEUROBIOLOGY OF DISEASE
- Interleukin-6 Serum Levels in Patients with Parkinson’s Disease
- (2009) Kerly Wollmeister Hofmann et al. NEUROCHEMICAL RESEARCH
- Caffeine Enhances Astroglia and Microglia Reactivity Induced by 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) in Mouse Brain
- (2009) Amit Khairnar et al. NEUROTOXICITY RESEARCH
- Progressive Dopaminergic Degeneration in the Chronic MPTPp Mouse Model of Parkinson’s Disease
- (2009) Nicoletta Schintu et al. NEUROTOXICITY RESEARCH
- Selective Vulnerability in Striosomes and in the Nigrostriatal Dopaminergic Pathway After Methamphetamine Administration
- (2009) Noelia Granado et al. NEUROTOXICITY RESEARCH
- Behavior, neurotransmitters and inflammation in three regimens of the MPTP mouse model of Parkinson's disease
- (2009) Dirk W. Luchtman et al. PHYSIOLOGY & BEHAVIOR
- The influence of microglia on the pathogenesis of Parkinson's disease
- (2009) Caitríona M. Long-Smith et al. PROGRESS IN NEUROBIOLOGY
- Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease
- (2008) Pramod Kumar et al. BEHAVIOURAL BRAIN RESEARCH
- Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease
- (2008) M. C. Pott Godoy et al. BRAIN
- Peripheral cytokines profile in Parkinson’s disease
- (2008) M. Reale et al. BRAIN BEHAVIOR AND IMMUNITY
- Expression of Peroxisome Proliferator-Activated Receptor-γ in Key Neuronal Subsets Regulating Glucose Metabolism and Energy Homeostasis
- (2008) David A. Sarruf et al. ENDOCRINOLOGY
- Peroxisome proliferator-activated receptorsγ (PPARγ) differently modulate the interleukin-6 expression in the peri-infarct cortical tissue in the acute and delayed phases of cerebral ischaemia
- (2008) Andreas Patzer et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The lipopolysaccharide Parkinson’s disease animal model: mechanistic studies and drug discovery
- (2008) Garima Dutta et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains
- (2008) Y YASUDA et al. JOURNAL OF NEUROIMMUNOLOGY
- Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt
- (2008) Bin Xing et al. Journal of Neuroinflammation
- Human Interleukin-10 Gene Transfer Is Protective in a Rat Model of Parkinson's Disease
- (2008) Louisa C Johnston et al. MOLECULAR THERAPY
- Regulation of Glial Cell Functions by PPAR- Natural and Synthetic Agonists
- (2008) Antonietta Bernardo et al. PPAR Research
- Mechanisms of anti-inflammatory and neuroprotective actions of PPAR-gamma agonists
- (2007) Ramya Kapadia Frontiers in Bioscience-Landmark
- Glial reactions in Parkinson's disease
- (2007) Patrick L. McGeer et al. MOVEMENT DISORDERS
- Protective properties afforded by pioglitazone against intrastriatal LPS in Sprague–Dawley rats
- (2007) Randy L. Hunter et al. NEUROSCIENCE LETTERS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now