Interleukin-1β Biosynthesis Inhibition Reduces Acute Seizures and Drug Resistant Chronic Epileptic Activity in Mice

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

The role of interleukin-1β in febrile seizures

(2009) James G. Heida et al.   BRAIN & DEVELOPMENT

A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1 

(2008) S. Balosso et al.   BRAIN

The role of cytokines in the pathophysiology of epilepsy

(2008) Annamaria Vezzani et al.   BRAIN BEHAVIOR AND IMMUNITY

Characteristics and clinical significance of subclinical seizures

(2008) Andro Zangaladze et al.   EPILEPSIA

Interleukin-1 (IL-1): A central regulator of stress responses

(2008) Inbal Goshen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7receptor-mediated IL-1β release

(2008) Liliana Bernardino et al.   JOURNAL OF NEUROCHEMISTRY

Communication between neurons and astrocytes: relevance to the modulation of synaptic and network activity

(2008) Tommaso Fellin   JOURNAL OF NEUROCHEMISTRY

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production

(2008) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Antagonism of peripheral inflammation reduces the severity of status epilepticus

(2008) Nicola Marchi et al.   NEUROBIOLOGY OF DISEASE

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2007) K. Boer et al.   EPILEPSY RESEARCH

Botulinum neurotoxin E (BoNT/E) reduces CA1 neuron loss and granule cell dispersion, with no effects on chronic seizures, in a mouse model of temporal lobe epilepsy

(2007) Flavia Antonucci et al.   EXPERIMENTAL NEUROLOGY

Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

(2007) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE