Role of Matrix Metalloproteinases and Therapeutic Benefits of Their Inhibition in Spinal Cord Injury

5-Carboxylate Substituted Piperazine-2-ones as Potent and Selective MMP-2 Inhibitors

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Matrix Metalloproteinase Inhibitors

(2010) György Dormán et al.   DRUGS

Matrix Metalloproteinases and Neurotrauma: Evolving Roles in Injury and Reparative Processes

(2010) Haoqian Zhang et al.   NEUROSCIENTIST

To bind zinc or not to bind zinc: An examination of innovative approaches to improved metalloproteinase inhibition

(2009) Jennifer A. Jacobsen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis

(2009) Lillian A Buhler et al.   BMC NEUROSCIENCE

Active Site Ring-Opening of a Thiirane Moiety and Picomolar Inhibition of Gelatinases

(2009) Christopher Forbes et al.   Chemical Biology & Drug Design

Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenylsulfonyl)ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors

(2009) Major Gooyit et al.   Chemical Biology & Drug Design

A Potent Gelatinase Inhibitor with Anti-Tumor-Invasive Activity and its Metabolic Disposition

(2009) Mijoon Lee et al.   Chemical Biology & Drug Design

Roles of Matrix Metalloproteinases in Flow-Induced Outward Vascular Remodeling

(2009) Ryo Ota et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury

(2009) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

Human umbilical cord blood stem cells upregulate matrix metalloproteinase-2 in rats after spinal cord injury

(2009) Krishna Kumar Veeravalli et al.   NEUROBIOLOGY OF DISEASE

Inhibition of MMP2/MMP9 After Spinal Cord Trauma Reduces Apoptosis

(2009) Alexis B. C. Dang et al.   SPINE

Minocycline and neurodegenerative diseases

(2008) Hye-Sun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Design, synthesis and evaluation of novel sulfonyl pyrrolidine derivatives as matrix metalloproteinase inhibitors

(2008) Xian-Chao Cheng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Multiphasic roles for matrix metalloproteinases after stroke

(2008) A ROSELL et al.   CURRENT OPINION IN PHARMACOLOGY

Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats

(2008) Megan Ryan Detloff et al.   EXPERIMENTAL NEUROLOGY

Carbamoylphosphonate Matrix Metalloproteinase Inhibitors 6:cis-2-Aminocyclohexylcarbamoylphosphonic Acid, A Novel Orally Active Antimetastatic Matrix Metalloproteinase-2 Selective InhibitorSynthesis and Pharmacodynamic and Pharmacokinetic Analysis

(2008) Amnon Hoffman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Matrix Metalloproteinase-9 Facilitates Glial Scar Formation in the Injured Spinal Cord

(2008) J.-Y. C. Hsu et al.   JOURNAL OF NEUROSCIENCE

Induction of MMP-9 Expression and Endothelial Injury by Oxidative Stress after Spinal Cord Injury

(2008) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Cardiac Uptake of Minocycline and Mechanisms for In Vivo Cardioprotection

(2008) Diego Romero-Perez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MMPs initiate Schwann cell-mediated MBP degradation and mechanical nociception after nerve damage

(2008) Hideo Kobayashi et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

(2008) Yasuhiko Kawasaki et al.   NATURE MEDICINE

Effect of cytokines on neuronal excitability

(2008) Maria Schäfers et al.   NEUROSCIENCE LETTERS

β-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: Part 2. Optimization of α-amino substituents

(2007) Shyh-Ming Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

MMPs in the central nervous system: Where the good guys go bad

(2007) S AGRAWAL et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Prevention of progressive joint destruction in collagen-induced arthritis in rats by a novel matrix metalloproteinase inhibitor, FR255031

(2004) Takeshi Ishikawa et al.   BRITISH JOURNAL OF PHARMACOLOGY