Article
Clinical Neurology
Hanan Khalil, Zakiyah F. Aldaajani, Mayis Aldughmi, Alham Al-Sharman, Tareq Mohammad, Raja Mehanna, Shaimaa El-Jaafary, Ahmed Dahshan, Mouna Ben Djebara, Walaa A. Kamel, Hanan A. Amer, Mohammed Farghal, Fatema Abdulla, Nouf Al-Talai, Muneer Abu Snineh, Nouha Farhat, Fatima A. Jamali, Rawan K. Matar, Heba S. Abdelraheem, Nesma A. M. Ghonimi, Mishal Abu Al-Melh, Sonia Elbhrawy, Majid S. Alotaibi, Shaimaa A. Elaidy, Shahad A. Almuammar, Jasem Y. Al-Hashel, Riadh Gouider, Hatem Samir, Chokri Mhiri, Matej Skorvanek, Jeffrey Lin, Pablo Martinez-Martin, Glenn T. Stebbins, Sheng Luo, Christopher G. Goetz, Jawad A. Bajwa
Summary: This study validated the Arabic-translated version of the MDS-UPDRS and confirmed its consistency with the English version in terms of factor structure. The Arabic version of the MDS-UPDRS has good construct validity in Arabic-speaking PD patients and has been designated as the official version. The study provides a roadmap for validating other MDS rating scales and demonstrates that underserved regions can actively mobilize efforts to improve clinical care, education, and research for PD.
MOVEMENT DISORDERS
(2022)
Article
Clinical Neurology
Jan Kasper, Simon B. Eickhoff, Svenja Caspers, Jessica Peter, Imis Dogan, Robert Christian Wolf, Kathrin Reetz, Juergen Dukart, Michael Orth
Summary: Kasper et al. found that in Huntington's disease, the functional integrity of the dopamine receptor-rich caudate nucleus plays a crucial role in maintaining network function. Loss of caudate functional integrity leads to motor signs independent of atrophy. This finding may have implications for other neurodegenerative diseases.
Article
Clinical Neurology
Valtteri Kaasinen, Filip Scheperjans, Mikko Karppa, Jaana Korpela, Anna Bruck, Jussi O. T. Sipila, Juho Joutsa, Juha Jarvela, Johanna Eerola-Rautio, Mika H. Martikainen, Katja Airaksinen, Glenn T. Stebbins, Pablo Martinez-Martin, Christopher G. Goetz, Jeffrey Lin, Sheng Luo, Eero Pekkonen
Summary: The study validated the Finnish version of UDysRS and identified subtle differences compared to the reference standard, possibly related to sample composition or disease status.
EUROPEAN NEUROLOGY
(2021)
Article
Clinical Neurology
Luis A. Sierra, Shelby B. Hughes, Clementina J. Ullman, Andrew Hall, Sarbesh R. Pandeya, Robin Schubert, Samuel A. Frank, Mark A. Halko, Jody Corey-Bloom, Simon Laganiere
Summary: This study aimed to replicate, validate, and further analyze the Loewenstein-Acevedo Scale for Semantic Interference and Learning (LASSI-L) in pre-motor manifest Huntington's disease (preHD). The results demonstrated that the LASSI-L can capture early cognitive changes in preHD, especially in participants who are far from diagnosis in the preHD stage. The LASSI-L is shown to be a sensitive, reliable, and efficient tool for detecting cognitive decline in preHD.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Joanna Siuda, Magdalena Boczarska-Jedynak, Slawomir Budrewicz, Jaroslaw Dulski, Monika Figura, Urszula Fiszer, Agata Gajos, Agnieszka Gorzkowska, Ewa Koziorowska-Gawron, Dariusz Koziorowski, Anna Krygowska-Wajs, Monika Rudzinska-Bar, Jaroslaw Slawek, Mateusz Tos, Magdalena Wojcik-Pedziwiatr, Jeffrey Lin, Sheng Luo, Pablo Martinez-Martin, Glenn T. Stebbins, Christopher G. Goetz, Grzegorz Opala
Summary: The study validated the Polish translation of the UDysRS and found that it shared a consistent factor structure with the Reference Standard Spanish version. The Official Polish UDysRS translation is recommended for use in clinical and research settings, providing a common ground for studying disease manifestations and progression across cultures.
NEUROLOGIA I NEUROCHIRURGIA POLSKA
(2021)
Article
Clinical Neurology
Esther Cubo, Sheng Luo, Pablo Martinez-Martin, Glenn T. Stebbins, Jeffrey Lin, Dongrak Choi, Alvaro Garcia-Bustillo, Pablo Mir, Diego Santos-Garcia, Marcos Serrano-Duenas, Mayela Rodriguez-Violante, Carlos Singer
Summary: This article summarizes the formal process of completing the MDS-NMS program and presents data on the first non-English version (Spanish). The results show that the Spanish version of MDS-NMS met the criteria to be designated as an official translation and is now available on the MDS website.
MOVEMENT DISORDERS CLINICAL PRACTICE
(2023)
Article
Otorhinolaryngology
Matteo Alicandri-Ciufelli, Luca Pingani, Francesco Maccarrone, Lukas Anschuetz, Davide Mariano, Gian Maria Galeazzi, Livio Presutti, Giulia Molinari
Summary: The Modena bleeding score is an effective method to evaluate bleeding during endoscopic sinus surgery. The study confirmed its reliability and clinical validity, and suggested its application in future research to assess the efficacy of surgical techniques, materials, or devices aimed at bleeding control during endoscopic sinus surgery.
BRAZILIAN JOURNAL OF OTORHINOLARYNGOLOGY
(2022)
Article
Psychology, Clinical
Alzbeta Muhlback, Wiebke Frank, Olga Klempirova, Ondrej Bezdicek, Lena Schmitt, Nina Hofstetter, G. Bernhard Landwehrmeyer, Jiri Klempir
Summary: The study showed that the cognitive battery is an accurate tool for assessing cognitive impairment in HD patients, with cognitive deficits worsening as the disease progresses and correlating with motor, functional impairment, and Disease Burden Score.
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
(2021)
Article
Clinical Neurology
Eva Wibbeler, Miriam Nickel, Christoph Schwering, Angela Schulz, Jonathan W. Mink
Summary: This study aimed to determine the validity and reliability of the UBDRS rating scale for CLN3 disease in an independent sample. After evaluating 13 individuals with CLN3 disease, it was concluded that UBDRS has excellent interrater reliability and construct validity.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
(2022)
Review
Clinical Neurology
Thomas Kinfe, Alessandro Del Vecchio, Martin Nussel, Yining Zhao, Andreas Stadlbauer, Michael Buchfelder
Summary: Huntington's Disease is a progressive neurological disorder with limited response to established therapeutics. Pallidal deep brain stimulation and neurorestorative strategies have shown potential for the treatment of refractory Huntington's disease. However, clinical trials have produced inconsistent results and these therapies remain experimental and not ready for clinical use.
EXPERT REVIEW OF NEUROTHERAPEUTICS
(2022)
Article
Clinical Neurology
Shuo Zhang, Xin Yang, Yingsheng Xu, Yongmei Luo, Dongsheng Fan, Xiaoxuan Liu
Summary: This study evaluated the usefulness of MUNIX technique in Kennedy disease and found a correlation between MUNIX and other clinical parameters. The MUNIX sum score was identified as an objective and reliable indicator of disease progression, showing potential for therapeutic clinical trials. MUNIX was more sensitive than other measures in assessing motor axon loss and axonal collateral reinnervation.
FRONTIERS IN NEUROLOGY
(2021)
Article
Neurosciences
Hannah M. Zipprich, Sarah Mendorf, Thomas Lehmann, Tino Prell
Summary: The study found that nonadherence is a common issue among Parkinson's disease (PD) patients, with factors such as male gender, cognitive decline, increased non-motor symptoms, comorbidities, and higher levels of depression associated with nonadherence. Quality of life was also correlated with similar factors but was not directly linked to nonadherence.
Article
Medicine, General & Internal
Heta Pavan Patel, M. Balaganapathy
Summary: The study aimed to culturally adapt and validate the KOOS-PF scale in Gujarati for early patellofemoral arthritis population. The analysis identified deficits in reliability and convergent validity of the Gujarati version of the scale, suggesting the need for a new condition-specific tool.
JOURNAL OF THE SCIENTIFIC SOCIETY
(2022)
Article
Peripheral Vascular Disease
Sung-Joon Park, Hwan Hoon Chung, Yun Hak Lee, Hyoung Nam Lee, Youngjong Cho, Sangjoon Lee, Seung Hwa Lee, Woo Young Yang
Summary: BPB using only 1% lidocaine can induce sensory loss while minimizing motor block. It can be safely applied in an outpatient clinic setting with relatively higher satisfaction.
JOURNAL OF VASCULAR ACCESS
(2023)