Multiplicity in confirmatory clinical trials: a case study with discussion from a JSM panel

An Overview of Statistical Planning to Address Subgroups in Confirmatory Clinical Trials

(2014) Gary G. Koch et al.   Journal of Biopharmaceutical Statistics

Multiple comparisons in complex clinical trial designs

(2013) H. M. James Hung et al.   BIOMETRICAL JOURNAL

Estimating Covariate-Adjusted Log Hazard Ratios in Randomized Clinical Trials Using Cox Proportional Hazards Models and Nonparametric Randomization Based Analysis of Covariance

(2013) Benjamin R. Saville et al.   Journal of Biopharmaceutical Statistics

Traditional multiplicity adjustment methods in clinical trials

(2013) Alex Dmitrienko et al.   STATISTICS IN MEDICINE

Planning and evaluating clinical trials with composite time-to-first-event endpoints in a competing risk framework

(2013) G. Rauch et al.   STATISTICS IN MEDICINE

An adaptive strategy for assessing regional consistency in multiregional clinical trials

(2012) Joshua Chen et al.   Clinical Trials

Ethnic Sensitive or Molecular Sensitive Beyond All Regions Being Equal in Multiregional Clinical Trials

(2012) Sue-Jane Wang et al.   Journal of Biopharmaceutical Statistics

Key multiplicity issues in clinical drug development

(2012) Alex Dmitrienko et al.   STATISTICS IN MEDICINE

Superchain procedures in clinical trials with multiple objectives

(2012) George Kordzakhia et al.   STATISTICS IN MEDICINE

Graphical approaches for multiple comparison procedures using weighted Bonferroni, Simes, or parametric tests

(2011) Frank Bretz et al.   BIOMETRICAL JOURNAL

Addressing Multiplicity Issues of a Composite Endpoint and Its Components in Clinical Trials

(2011) Mohammad F. Huque et al.   Journal of Biopharmaceutical Statistics

Multiple Testing Procedures in Two Pivotal Clinical Trials for Approval of a New Pharmaceutical Product

(2011) Brian L. Wiens   Journal of Biopharmaceutical Statistics

Regional differences in multinational clinical trials: anticipating chance variation

(2010) Ian C Marschner   Clinical Trials

Consideration of regional difference in design and analysis of multi-regional trials

(2010) H. M. James Hung et al.   PHARMACEUTICAL STATISTICS

Estimating Covariate-Adjusted Incidence Density Ratios for Multiple Time Intervals in Clinical Trials Using Nonparametric Randomization-Based ANCOVA

(2010) Benjamin R. Saville et al.   Statistics in Biopharmaceutical Research

Stratified Multivariate Mann–Whitney Estimators for the Comparison of Two Treatments with Randomization Based Covariance Adjustment

(2010) Atsushi Kawaguchi et al.   Statistics in Biopharmaceutical Research

Some Controversial Multiple Testing Problems in Regulatory Applications

(2009) H. M. James Hung et al.   Journal of Biopharmaceutical Statistics

A graphical approach to sequentially rejective multiple test procedures

(2008) Frank Bretz et al.   STATISTICS IN MEDICINE