Article
Oncology
Marine Lottin, Alexandre Escande, Luc Bauchet, Marie Albert-Thananayagam, Mael Barthoulot, Matthieu Peyre, Mathieu Boone, Sonia Zouaoui, Jacques Guyotat, Guillaume Penchet, Johan Pallud, Henry Dufour, Evelyne Emery, Michel Lefranc, Sebastien Freppel, Houman Namaki, Edouard Gueye, Jean-Jacques Lemaire, Bertrand Muckensturm, Robin Srour, Stephane Derrey, Apolline Monfilliette, Jean-Marc Constans, Claude-Alain Maurage, Bruno Chauffert, Nicolas Penel
Summary: This retrospective study analyzed the clinical outcomes of 88 patients with intracranial solitary fibrous tumours (iSFTs). Gross tumour resection was found to be beneficial for prognosis and reduced local recurrence without impacting overall survival. High-grade tumours were associated with poorer progression-free survival and local recurrence-free survival. More than 40% of patients experienced local recurrence and were mostly treated with surgery and radiotherapy. The first relapse was a turning point in iSFT evolution, with shorter recurrence intervals over time. Managing repeated recurrence and disseminated disease remains challenging and local techniques should be considered.
Article
Oncology
Ziyan Chen, Ningrong Ye, Nian Jiang, Qi Yang, Siyi Wanggou, Xuejun Li
Summary: Our study found that SFT/HPC showed more invasion to venous sinus (p = 0.001), more cystic components (p < 0.001), and more heterogeneous enhancement patterns (p < 0.001). The deep learning model achieved a high classification accuracy of 0.889 with an AUC of 0.91 in the validation set. Feature maps demonstrated distinct clustering of SFT/HPC and meningioma in the training and test cohorts, and the attention of the deep learning model mainly focused on the tumor bulks representing the solid texture features for discrimination.
FRONTIERS IN ONCOLOGY
(2022)
Review
Oncology
Alexander J. Allen, Dominic Angelo Labella, K. Martin Richardson, Jason P. Sheehan, Charles R. Kersh
Summary: This case report describes the successful treatment of a rare and aggressive solitary fibrous tumor using a combination of Gamma Knife and linear accelerator-based radiosurgery. The novel multi-fraction radiosurgery technique used in this study effectively controlled tumor recurrence while minimizing complication risk.
FRONTIERS IN ONCOLOGY
(2022)
Review
Medicine, General & Internal
Angela Sardaro, Paolo Mammucci, Antonio Rosario Pisani, Dino Rubini, Anna Giulia Nappi, Lilia Bardoscia, Giuseppe Rubini
Summary: Solitary fibrous tumor (SFT) of the central nervous system is a rare brain tumor with malignant behavior and imaging plays a crucial role in treatment decision-making, with emerging use of PET, although the choice of radiotracers is still debated.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Yanghua Fan, Panpan Liu, Yiping Li, Feng Liu, Yu He, Liang Wang, Junting Zhang, Zhen Wu
Summary: Our clini-radiomic model showed great performance and high sensitivity in the differential diagnosis of intracranial hemangiopericytoma and angiomatous meningioma, and could contribute to non-invasive development of individualized diagnosis and treatment for these patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Jianbiao Xiao, Lanwei Xu, Yi Ding, Wei Wang, Fen Chen, Yangshu Zhou, Fengjiao Zhang, Qiyuan Zhou, Xuehui Wu, Junpeng Li, Li Liang, Yee-Min Jen
Summary: In this retrospective analysis, post-operative radiotherapy did not improve the local control rates or survival in intracranial hemangiopericytoma patients. The local control rates after intensity-modulated radiotherapy (IMRT) and stereotactic radiosurgery (SRS) were similar, even though IMRT had a higher biological dose compared to SRS.
Article
Clinical Neurology
Daisuke Yamashita, Satoshi Suehiro, Shohei Kohno, Shiro Ohue, Yawara Nakamura, Daisuke Kouno, Yoshihiro Ohtsuka, Masahiro Nishikawa, Shirabe Matsumoto, Joshua D. Bernstock, Shuko Harada, Yosuke Mizuno, Riko Kitazawa, Takanori Ohnishi, Takeharu Kunieda
Summary: Intracranial anaplastic hemangiopericytoma (AHPC) is a rare and malignant subset of solitary fibrous tumor/hemangiopericytoma (SFT/HPC) with poor prognosis and the need for specific clinical and immunohistochemical criteria for diagnosis. Analysis of different IHC markers shows that nuclear expression of STAT6 has the highest specificity for SFT/HPC, while other markers like ALDH1 and CD34 also play important roles. Distinguishing between AHPC and other tumors like meningioma is crucial for determining appropriate treatment strategies.
NEUROSURGICAL REVIEW
(2021)
Article
Medicine, General & Internal
Zhicheng Huang, Dongqin Dai, Guangcai Tang
Summary: This study reports a rare case of intracranial SFT with significantly decreased signal intensity in T2 weighted images, which provides an important supplement to the rare imaging findings of intracranial SFT.
Review
Clinical Neurology
Sricharan Gopakumar, Visish M. Srinivasan, Caroline C. Hadley, Adrish Anand, Marc Daou, Patrick J. Karas, Jacob Mandel, Shankar P. Gopinath, Akash J. Patel
Summary: Intracranial solitary fibrous tumors (ISFTs) are rare neoplasms originating from the meninges and are challenging to treat, particularly when located in the skull base. Visual disturbances and headaches are common presenting symptoms, with tumor recurrence occurring in around a quarter of cases following surgical resection.
WORLD NEUROSURGERY
(2021)
Article
Computer Science, Artificial Intelligence
Yanan Li, Zhimin Wang, Rongbing Han, Shangshang Shi, Jiaxin Li, Ruimin Shang, Haiyong Zheng, Guoqiang Zhong, Yongjian Gu
Summary: Quantum neural network (QNN) is a promising direction for near-term noisy intermediate-scale quantum (NISQ) devices to outperform classical resources. However, there is still a lack of a canonical model for quantum recurrent neural network (QRNN), hindering research in quantum deep learning. In this work, a new type of QRNN is proposed, which is built with hardware-efficient quantum recurrent blocks (QRBs) stacked in a staggered way to reduce the coherent time requirement of quantum devices. Numerical experiments demonstrate that the proposed QRNN model achieves better prediction accuracy and can capture the details of temporal sequence data.
Review
Clinical Neurology
Enrico Giordan, Elisabetta Marton, Alexandra M. Wennberg, Angela Guerriero, Giuseppe Canova
Summary: Patients with meningeal SFT/HPCs have high rates of recurrence and metastasis, mostly occurring within the first 5 years after diagnosis. Spinal and intracranial SFT/HPCs exhibit similar behavior, but spinal SFT/HPCs tend to develop metastases and recurrences at a shorter interval of time. Careful follow-up for spinal SFT/HPCs is recommended as spinal cases seem to be slightly more aggressive and require more attention.
NEUROSURGICAL REVIEW
(2021)
Review
Oncology
Danielle Golub, Joshua D. Mcbriar, Hayley Donaldson, Taylor Wong, Prashin Unadkat, Timothy G. White, Eric T. Quach, Sara Haddock, Bhargava Chitti, Yonah Ziemba, Anuj Goenka, Samuel Singer, Michael Schulder, Amir R. Dehdashti
Summary: Stereotactic radiosurgery (SRS) is a safe and effective treatment for intracranial solitary fibrous tumors (SFTs). Increasing the SRS margin dose may improve local tumor control (LTC). Understanding the aggressive biology of SFTs and the tolerated adjuvant SRS parameters supports potentially earlier use of SRS in the postoperative treatment paradigm for intracranial SFTs.
JOURNAL OF NEURO-ONCOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Xiaojing Li, Mingwang Yang, Jianfang Cao, Hua Gu, Weijian Liu, Tianping Xia, Wen Sun, Jiangli Fan, Xiaojun Peng
Summary: This study presents a novel prodrug-hemicyanine conjugate (Cy-azo) that achieves enhanced photothermal therapy and sequential hypoxia-activated chemotherapy. The Cy-azo conjugate exhibits high photothermal conversion efficiency and releases the activated drug in the tumor hypoxic microenvironment, effectively killing cancer cells and reducing the toxic side effects of chemotherapy. Furthermore, encapsulating Cy-azo into polymer nanoparticles enhances its tumor accumulation and overall photothermal conversion efficiency.
ACS MATERIALS LETTERS
(2022)
Article
Oncology
Joo Ho Lee, Seung Hyuck Jeon, Chul-Kee Park, Sung-Hye Park, Hong In Yoon, Jong Hee Chang, Chang-Ok Suh, Su Jeong Kang, Do Hoon Lim, In Ah Kim, Jin Hee Kim, Jung Ho Im, Sung-Hwan Kim, Chan Woo Wee, Il Han Kim
Summary: This multicenter study confirms the role of postoperative radiotherapy in disease control for intracranial solitary fibrous tumor/hemangiopericytoma patients. Regardless of surgical extent and grade, radiotherapy can significantly improve local control and progression-free survival.
CANCER RESEARCH AND TREATMENT
(2022)
Review
Clinical Neurology
Ahmad A. Ballout, David S. Liebeskind
Summary: This article summarizes studies investigating the relationship between biomarkers and their role in predicting recurrent stroke risk in intracranial atherosclerotic disease.
FRONTIERS IN NEUROLOGY
(2022)