Article
Food Science & Technology
Sarah Auguste, Bing Yan, Maolin Guo
Summary: Polyphenols found in tea can induce mitophagy in human fibroblast cells, and the induction of mitophagy may play an important role in the anti-aging mechanism of tea.
Article
Biophysics
Xu Ding, Fengxia Wang, Hui Hu, Sarah Imhanria, Wei Wang, Ji Zhang
Summary: This study reports a facile and green strategy of fabricating catkin-like CuAg nanocomposites using tea-polyphenols as the reduction agent. The nanocomposites exhibit a catkin-like special morphology as characterized by physical characterizations. The electrochemical detection hydrogen peroxide (H2O2) results demonstrate the good sensitivity, stability, and anti-interference of the catkin-like CuAg nanocomposites, which can detect H2O2 without any additional mediator or enzyme.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Review
Chemistry, Multidisciplinary
Chang Xu, Su Zhou, Hao Hu, Haizhao Song, Xiangchun Zhang, Xinyu Feng, Yunyun Yang, Yani Pan, Shuying Gong, Fangyuan Fan, Ping Chen, Qiang Chu
Summary: Tea polyphenols, as active ingredients in tea, have excellent physicochemical properties and bioactivities, making them versatile in material synthesis. Tea polyphenol-derived materials are environmentally friendly, biocompatible and retain potent bioactivities such as antioxidant, antibacterial and anti-cancer properties.
Article
Food Science & Technology
Sirui Qin, Ruyi Li, Mianhong Chen, Fanke Zeng, Yaping Dai, Guang Wu, Wei Zhou, Jihua Li
Summary: Oat milk tea can curdle when mixed with tea, affecting consumer acceptability. This study investigated the stability and polyphenol bioaccessibility of oat milk tea model systems. The addition of green tea extract influenced stability, with higher fat content resulting in greater stability. Tea polyphenols were stable in oral and stomach digestion stages but degraded in the small intestine stage. The bioaccessibility of tea polyphenols was higher in high-fat oat milk tea models, especially at low green tea extract concentrations.
Article
Multidisciplinary Sciences
Eunee Lee, Seungjoon Lee, Jae Jin Shin, Woochul Choi, Changuk Chung, Suho Lee, Jihye Kim, Seungmin Ha, Ryunhee Kim, Taesun Yoo, Ye-Eun Yoo, Jisoo Kim, Young Woo Noh, Issac Rhim, Soo Yeon Lee, Woohyun Kim, Taekyung Lee, Hyogeun Shin, Il-Joo Cho, Karl Deisseroth, Sang Jeong Kim, Joo Min Park, Min Whan Jung, Se-Bum Paik, Eunjoon Kim
Summary: The NMDARs and gap junctions in cortical PV interneurons are involved in modulating burst firing, which ultimately affects social behavior.
NATURE COMMUNICATIONS
(2021)
Review
Biochemistry & Molecular Biology
Sergio Perez-Burillo, Beatriz Navajas-Porras, Alicia Lopez-Maldonado, Daniel Hinojosa-Nogueira, Silvia Pastoriza, Jose angel Rufian-Henares
Summary: Green tea can influence gut microbiota by either stimulating the growth of specific species or hindering the development of detrimental ones, benefiting health through beneficial bacteria or microbial bioactive metabolites. The inter-relation between green tea and gut microbiota is crucial for many health promoting effects of green tea, with the ability to correct microbial dysbiosis in conditions like obesity or cancer. Tea compounds influence the growth of bacterial species involved in inflammatory processes, potentially impacting the development of chronic diseases.
Article
Chemistry, Applied
Jordan Teixeira Oliveira, Fernanda Machado da Costa, Taiciane Goncalvez da Silva, Greice Dotto Simoes, Elisa dos Santos Pereira, Paola Quevedo da Costa, Robson Andreazza, Paulo Cavalheiro Schenkel, Simone Pieniz
Summary: The study characterized the physical-chemical, antioxidant, and enzymatic properties of green tea and kombucha. Kombucha had lower pH, higher acidity, and solids content compared to green tea. Both green tea and kombucha showed significant antioxidant capacity. While both beverages showed a significant reduction in lipid peroxidation in the neutralized pH TBARS analysis, kombucha exhibited pro-oxidant activity in its natural form. Both beverages also showed significant inhibitory activity of the alpha-glucosidase enzyme, with green tea presenting superior inhibitory potential.
Review
Biochemistry & Molecular Biology
Shuzhen Wang, Zhiliang Li, Yuting Ma, Yan Liu, Chi-Chen Lin, Shiming Li, Jianfeng Zhan, Chi-Tang Ho
Summary: This review summarizes the recent studies on the immune-potentiating effects and corresponding mechanisms of tea polyphenols, especially EGCG and ECG, and discusses the benefits towards immune-related diseases.
Review
Nutrition & Dietetics
Jun Guo, Kai Li, Yajun Lin, Yinghua Liu
Summary: Aging is a key factor in cardiovascular diseases, which become more prevalent and severe with age. Understanding the mechanisms and interventions of cardiovascular aging is crucial for healthy aging. Tea polyphenols (TPs) are compounds found in tea leaves and have various effects on cardiovascular health. This article provides a detailed review of tea classification, composition, and its effects on cardiovascular diseases, including hypertension control, cholesterol reduction, antioxidant and anti-inflammatory abilities, as well as improving endothelial function and thrombosis prevention.
FRONTIERS IN NUTRITION
(2023)
Review
Plant Sciences
Susmit Mhatre, Tishya Srivastava, Shivraj Naik, Vandana Patravale
Summary: This study reviewed the antiviral activities of tea polyphenols and their interactions with SARS-CoV-2, indicating significant potential in the treatment and prophylaxis of COVID-19. In particular, theaflavin-3,3'-digallate (TF3) showed significant binding with viral receptors, highlighting the efficacy of tea polyphenols against COVID-19.
Article
Chemistry, Applied
Si Tan, Guangzhen Xin, Ruobing Xie, Xiaowen Wu, Wenfeng Li
Summary: The addition of green tea polyphenols improves the physiochemical stability of mango powder, maintaining its color and antioxidant activities, and inhibiting the degradation of ascorbic acid during storage.
Article
Multidisciplinary Sciences
Sybren F. de Kloet, Bastiaan Bruinsma, Huub Terra, Tim S. Heistek, Emma M. J. Passchier, Alexandra R. van den Berg, Antonio Luchicchi, Rogier Min, Tommy Pattij, Huibert D. Mansvelder
Summary: The study identifies four distinct populations of prefrontal neurons projecting to different sub-regions of the striatum and thalamus, each playing a discrete role in the regulation of cognitive control. Dorsal and ventral mPFC circuits exhibit differential synaptic inputs to postsynaptic striatal and thalamic neurons, potentially amplifying distinct pathways underlying cognitive control. Chemogenetic silencing of specific mPFC projections to thalamic subregions oppositely regulate cognitive control, highlighting the complex mechanisms involved in behavior regulation.
NATURE COMMUNICATIONS
(2021)
Article
Food Science & Technology
Arpan Singha Deo, P. J. Asheela Devi, K. S. Sijisha, R. Anusha, Tripti Mishra, Siby Mathew, K. Mathew Abraham, R. Jagadish, S. Priya
Summary: The study compared the antioxidant, anticancer, and anti-inflammatory activities of green tea, orthodox black tea, and CTC black tea. The results showed that green tea had higher antioxidant and anticancer activities and exhibited the best anti-inflammatory effects.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Acoustics
Shuyi Li, Dan Lei, Zhenzhou Zhu, Jie Cai, Maela Manzoli, Laszlo Jicsinszky, Giorgio Grillo, Giancarlo Cravotto
Summary: The study showed that high-intensity ultrasound treatment could accelerate the interaction between inulin and tea polyphenols, leading to the formation of complexes. Spectral analysis confirmed the formation of hydrogen bonds between saccharides and phenols.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Spectroscopy
Chengxiang Chu, Xianfeng Wang, Yuanyi Deng, Yi Ma, Chengyue Zou, Mei Yang, Huibo Luo, Danqun Huo, Changjun Hou
Summary: A facile and rapid fluorescence sensor array based on Tb(III) and Eu(III) doped Zr(IV) metal-organic frameworks was proposed for discriminating Chinese green tea. The large porosity of Tb@UiO-66-(COOH)2 and Eu@UiO-66-(COOH)2 allowed the coordination of phenolic hydroxyl groups of tea polyphenols with free carboxylic acid groups inside the pores, leading to the fluorescence quenching effect. Through Hierarchy Cluster Analysis and Linear Discrimination Analysis, the fluorescence sensor array successfully classified tea polyphenols and discriminated different categories and grades of green tea samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Review
Neurosciences
Shu-Han Liu, Yang Du, Lei Chen, Yong Cheng
Summary: This review provides an overview of the structural changes of glial cells in major psychiatric diseases such as schizophrenia, bipolar disorder, and major depressive disorder. The findings suggest that astrocytes, microglial cells, and oligodendrocytes exhibit specific patterns of changes in each disease.
MOLECULAR NEUROBIOLOGY
(2022)
Article
Cell Biology
Yang Du, Ji-Hui Dong, Lei Chen, Hua Liu, Guang-En Zheng, Guang-Yang Chen, Yong Cheng
Summary: This study reveals the potential role of exosomal metabolite dysregulation in the onset and/or development of bipolar disorder (BD) and suggests that blood exosomal metabolites are strong candidates to inform the diagnosis of BD.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2022)
Review
Neurosciences
Yang-wen Ai, Yang Du, Lei Chen, Shu-Han Liu, Qing-shan Liu, Yong Cheng
Summary: This study systematically reviewed the connection between brain inflammation markers and schizophrenia, bipolar disorder, and major depressive disorder. The results showed significant variations in the expression of inflammatory markers in these disorders, possibly influenced by various factors.
MOLECULAR NEUROBIOLOGY
(2023)
Review
Neurosciences
Hua Liu, Shan Lan, Xiao-Jie Shi, Fang-Cheng Fan, Qing-Shan Liu, Lin Cong, Yong Cheng
Summary: MicroRNAs (miRNAs) play a crucial role in the development of neurodegenerative disorders, particularly amyotrophic lateral sclerosis (ALS). Through a comprehensive systematic review and meta-analysis, the study identified elevated levels of miR-206, miR-133b, and miR-338-3p in patients with ALS compared to healthy controls. These findings suggest that miR-206, miR-133b, and miR-338-3p may serve as potential promising biomarkers for ALS, indicating their importance in the pathogenesis and progression of the disease.
BRAIN RESEARCH BULLETIN
(2023)
Article
Psychiatry
Xiao-Lin Zhong, Yang Du, Lei Chen, Yong Cheng
Summary: This paper reviews the functional roles and abnormal expression of long noncoding RNAs (lncRNAs) in the development, diagnosis, and treatment of depression, suggesting that lncRNAs may serve as biomarkers and potential therapeutic targets for depression.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Neurosciences
Fan Luo, Zimo Zhu, Yang Du, Lei Chen, Yong Cheng
Summary: Postpartum depression is a serious mood disorder that occurs after childbirth and can have lifelong consequences for women and their families. It is influenced by various risk factors, including environmental and genetic factors. Gene-environment interactions play a role in postpartum depression, as evidenced by studies on genes related to neurotransmitters, the HPA axis, and the kynurenine pathway. However, the conclusions regarding these risk factors, especially genetic factors, are not consistent, and further research is needed to understand the heritability and susceptibility of postpartum depression.
MOLECULAR NEUROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yang Du, Lei Chen, Mei-Chen Yan, Yan-Li Wang, Xiao-Lin Zhong, Chen-Xi Xv, Yao-Bo Li, Yong Cheng
Summary: A meta-analysis of 54 studies revealed that patients with autism spectrum disorders (ASDs) have altered levels of neurometabolites in specific brain regions compared to healthy controls. Lower levels of N-acetyl-aspartate-containing compound (NAA), choline-containing compound (Cho), and NAA/(creatine-containing compound) Cr ratios in the gray matter, as well as lower levels of NAA and glutamate + glutamine (Glx) in the white matter, were observed in ASD patients. Additionally, the frontal cortex showed decreased NAA and gamma-aminobutyric acid (GABA) levels, NAA/Cr ratios, and increased glutamate (Glu) levels. These findings suggest that neurometabolite alterations in specific brain regions are associated with ASD, and age is a confounding factor for certain neurometabolite levels in patients with ASD.
MOLECULAR PSYCHIATRY
(2023)
Review
Behavioral Sciences
Heng-Chang Zhang, Yang Du, Lei Chen, Zeng-Qiang Yuan, Yong Cheng
Summary: Schizophrenia-related symptoms, including positive, negative, and cognitive symptoms, have serious effects on public health, affecting approximately 1% of the population. Recent studies have shown that besides the traditional dopaminergic pathway, the etiology of schizophrenia involves neuronal networks such as glutamate, GABA, serotonin, BDNF, oxidative stress, inflammation, and the immune system. MicroRNAs (miRNAs), small noncoding RNA molecules, have been identified as potential factors in the pathophysiology of schizophrenia, influencing these systems. Understanding how changes in miRNAs affect critical signaling pathways could lead to improved approaches in treating and diagnosing schizophrenia.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Psychiatry
Fang-Cheng Fan, Yang Du, Wen-Hui Zheng, Y. Peng Loh, Yong Cheng
Summary: This study demonstrates that conditional knockout of neuronal CPE leads to learning and memory deficits, hippocampal and amygdala degeneration, and reduced neurogenesis in mice.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Pharmacology & Pharmacy
Mulan Bao, Rengui Bade, Hua Liu, Battseren Tsambaa, Guo Shao, Almaz Borjigidai, Yong Cheng
Summary: AS-IV from Huangqi may regulate inflammation and microglial activation in AD via EGFR-dependent pathways. EGFR and IL-113 could be important targets that co-regulate downstream molecular functions in the treatment of AD.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Hua Liu, Yang Du, Lian Lin Liu, Qing Shan Liu, He Hui Mao, Yong Cheng
Summary: This study evaluated the neuroprotective and anti-depressive effects of Mogroside V (MGV), the main component of Siraitia grosvenorii (SG) extract, both in vitro and in vivo. MGV demonstrated a protective effect on PC12 cells with corticosterone-induced injury and relieved depressive symptoms in the chronic unpredictable mild stress (CUMS) depression model. Additionally, MGV significantly reduced inflammatory and oxidative stress levels, and decreased apoptosis in hippocampal nerve cells through the inhibition of the BDNF/TrkB/AKT pathway.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2023)
Article
Neurosciences
Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Cheng
Summary: Autism spectrum disorders (ASD) are a complex group of neurodevelopmental disorders caused by genetic and environmental factors. This study investigated gene expression abnormalities in the hippocampus and prefrontal cortex of a rat model of ASD, and found significant differences in gene expression between the ASD model and control groups. Additionally, a negative regulatory network of miRNAs-mRNAs was identified, which may play a key role in the development of ASD.
MOLECULAR NEUROBIOLOGY
(2023)
Article
Psychiatry
Qiang Fu, Rui Qiu, Lei Chen, Yuewen Chen, Wen Qi, Yong Cheng
Summary: This study provides the first evidence that listening to music can prevent stress-induced depression and anxiety-like behaviors in mice. The results show that music restores serum corticosterone levels and prevents oxidative stress, inflammation, and neurotrophic factor deficits in the mouse brain.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Plant Sciences
Xiao-Jie Shi, Yang Du, Lei Chen, Yuan-Yuan Chen, Man Luo, Yong Cheng
Summary: The Mongolian medicine Nuangong Qiwei Pill (NGQW) is a folk prescription used for gynecological diseases. This study aimed to investigate the mechanism of NGQW and macelignan in treating polycystic ovary syndrome (PCOS). The results showed that NGQW and macelignan regulate the secretion ability of ovarian granulosa cells through the TGF-β3/Smad/Cyp19a1 signaling pathway, thus treating PCOS.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Clinical Neurology
Yong-Hang Li, Wei Huang, Man-Yu Xiao, Shi-Qing Huang, Hui Chen, Zai-Fang Li, Xue-Song Li, Yong Cheng
Summary: This study found differences in CYP2D6 gene polymorphism and metabolic activity between Han and Tibetan schizophrenia patients.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)
Article
Neurosciences
Song Xue, Feng Kong, Yiying Song, Jia Liu
Summary: This study used resting-state functional magnetic resonance imaging to explore the relationship between individual's spontaneous neural activity and social interaction anxiety in a nonclinical population. The results showed that social interaction anxiety was correlated with the fractional amplitude of low-frequency fluctuations in several brain regions, and that emotional intelligence partially mediated this relationship. This study provides evidence for the neural basis of social interaction anxiety in the normal population and highlights the role of emotional intelligence in this anxiety.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Katsuyuki Yamaguchi, Takuya Yazawa
Summary: This study provides morphometric data on the development of the human medullary arcuate nucleus (AN) by examining the brains of preterm and perinatal infants. The results show that AN morphology demonstrates asymmetry and individual variability during the fetal period. The volume and neuronal number of AN increase exponentially with age, while neuronal density decreases exponentially. The AN may undergo neuron death and neuroblasts production after mid-gestation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zhan Zhou, Weixin Dai, Tianxiao Liu, Min Shi, Yi Wei, Lifei Chen, Yubo Xie
Summary: Studies have shown that propofol-induced neurotoxicity is caused by disruption of mitochondrial fission and fusion, leading to an energy supply imbalance for developing neurons. Healthy mitochondria released by astrocytes can migrate to compromised neurons to mitigate propofol-induced neurotoxicity, but the exact mechanisms involved still need further clarification.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
An Chen, Song Hao, Yongpeng Han, Yang Fang, Yibei Miao
Summary: This study explores the efficacy of two forms of BCI attention training games and finds that physical games may be more effective than video games. The research also offers valuable insights for future game design from a neuroscience perspective.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lina Liu, Luran Liu, Yunting Lu, Tianyuan Zhang, Wenting Zhao
Summary: This study reveals that GDI1 serves as a potential diagnostic biomarker for AD and inhibition of GDI1 can attenuate Aβ-induced neurotoxicity. The findings offer new insights for the treatment of AD.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Zahra Gholami, Ava Soltani Hekmat, Ali Abbasi, Kazem Javanmardi
Summary: This study investigated the effects of alamandine on allodynia in a rat model and found the presence of MrgD receptors in the vlPAG and RVM regions. Microinjection of alamandine resulted in a significant increase in paw withdrawal threshold and could be blocked by an MrgD receptor antagonist. Upregulation of MrgD receptor expression following allodynia induction suggests a potential compensatory mechanism in response to pain.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Mingliang Xu, Lei Xia, Junjie Li, Yehong Du, Zhifang Dong
Summary: This study found that DHF effectively alleviates sevoflurane-induced cognitive impairment in developing mice by restoring the balance between tau O-GlcNAcylation and phosphorylation. Therefore, DHF has the potential to be a therapeutic agent for treating cognitive impairment associated with anesthetics, such as sevoflurane.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Tsubasa Mitsutake, Hisato Nakazono, Takanori Taniguchi, Hisayoshi Yoshizuka, Maiko Sakamoto
Summary: The posterior parietal cortex plays a crucial role in postural stability, and transcranial electrical stimulation of this region can modulate physical control responses. This study found that cathodal stimulation significantly decreased joint angular velocity in multiple directions, while there were no significant differences with transcranial random noise stimulation.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xishuai Yang, Wei Zhang, Xueli Chang, Zuopeng Li, Runquan Du, Junhong Guo
Summary: This study aims to evaluate the efficacy of low-dose rituximab (RTX) in patients with muscle-specific kinase antibody positive myasthenia gravis (MuSK-MG). The results showed that low-dose RTX treatment led to significant improvements in clinical symptoms and quality of life for patients with MuSK-MG.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Jian Zhang, Shunyuan Guo, Rong Tao, Fan Wang, Yihong Xie, Huizi Wang, Lan Ding, Yuejian Shen, Xiaoli Zhou, Junli Feng, Qing Shen
Summary: This study established an Alzheimer's disease (AD) model of zebrafish induced by AlCl3 and found that marine-derived plasmalogens (Pls) could alleviate cognitive impairments of AD zebrafish by reversing athletic impairment and altering the expression levels of genes related to oxidative stress, ferroptosis, synaptic dysfunction, and apoptosis.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Lu Li, Jiaqi Ren, Qi Fang, Liqiang Yu, Jintao Wang
Summary: ICU-AW is a common and severe neuromuscular complication in critically ill patients. Electrophysiological examination is essential for accurate diagnosis and early prediction of the disease. This study aimed to establish and validate an ICU-AW predictive model in SIRS patients, providing a practical tool for early clinical prediction.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Ahmad Alipour, Roghayeh Mohammadi
Summary: The present study aimed to investigate the separate and combined effects of anodal transcranial direct current stimulation (tDCS) over the primary motor cortex (M1) and left dorsolateral prefrontal cortex (F3) regions on pain relief in patients with type-2 diabetes suffering from neuropathic pain (NP). The results showed that tDCS had the potential to induce pain relief in patients with type-2 diabetes suffering from NP. The mean perceived pain intensity in the posttest was lower in the M1 stimulation group than in the F3 stimulation group. However, more trials with larger sample sizes are necessary to define clinically relevant effects.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Eduardo J. Fusse, Franciele F. Scarante, Maria A. Vicente, Mariana M. Marrubia, Flavia Turcato, Davi S. Scomparin, Melissa A. Ribeiro, Maria J. Figueiredo, Tamires A. V. Brigante, Francisco S. Guimaraes, Alline C. Campos
Summary: Repeated exposure to psychosocial stress alters the endocannabinoid system and affects brain regions associated with emotional distress. Enhancing the effects of endocannabinoids through pharmacological inhibition induces an anti-stress behavioral effect, possibly mediated by the mTOR signaling pathway.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Giulia Agostoni, Luca Bischetti, Federica Repaci, Margherita Bechi, Marco Spangaro, Irene Ceccato, Elena Cavallini, Luca Fiorentino, Francesca Martini, Jacopo Sapienza, Mariachiara Buonocore, Michele Francesco D'Incalci, Federica Cocchi, Carmelo Guglielmino, Roberto Cavallaro, Marta Bosia, Valentina Bambini
Summary: This study found a general impairment in humor comprehension in individuals with schizophrenia, with mental jokes being more difficult for both patients and controls. Humor comprehension was closely associated with the patients' overall pragmatic and linguistic profile, while the association with Theory of Mind (ToM) was minimal. Another notable finding was the increased appreciation of humor in individuals with schizophrenia, who rated jokes as funnier than controls did, regardless of whether they were correctly or incorrectly completed. The funniness ratings were not predicted by any measure, suggesting a dimension of humor untied to cognition or psychopathology.
NEUROSCIENCE LETTERS
(2024)
Article
Neurosciences
Xiuping Gong, Qi Li, Yang Liu
Summary: This study demonstrates that Sev targets CREBBP to inhibit ALG13 transcription, leading to hippocampal damage and cognitive impairment.
NEUROSCIENCE LETTERS
(2024)
