期刊
NEUROSCIENCE LETTERS
卷 469, 期 1, 页码 135-140出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2009.11.060
关键词
Neurotrophins; GDNF family of neurotrophic factors; Sciatic nerve; Schwann cell
资金
- Wellcome Trust [067952]
- Estonian Ministry of Education and Research [0140143]
- Estonian Science Foundation [7257]
Ligands of NGF and GDNF families of neurotrophic factors have important functions in the development of the vertebrate peripheral nervous system (PNS). It has been established that they also play key roles in the regeneration of PNS. Expression patterns of NGF and GDNF family members and their receptors have mostly been analyzed during regeneration, and less during development of the PNS. We describe the expression of mRNAs encoding these neurotrophic factors and their receptors during development of rat sciatic nerve and in three modes of differentiation of cultured rat Schwann cells. Our results demonstrate specific expression patterns of NGF and GDNF family ligands and their receptors during differentiation of Schwann cells in vivo and in vitro. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据