期刊
NEUROSCIENCE LETTERS
卷 433, 期 2, 页码 87-92出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.neulet.2007.12.065
关键词
parietal; coherence; stroke; ideomotor apraxia; plasticity
资金
- Intramural NIH HHS [Z01 NS002669-23] Funding Source: Medline
We sought to determine whether coherent networks which circumvent lesioned cortex are seen in patients with ideomotor apraxia (IMA) while performing tool-use pantomimes. Five normal subjects and five patients with IMA (three patients with corticobasal degeneration and two with left hemisphere stroke) underwent 64-channel EEG recording while performing three tool-use pantomimes with their left hand in a self-paced manner. Beta band (20-22 Hz) coherence indicates that normal subjects have a dominant left hemisphere network responsible for praxis preparation, which was absent in patients. Corticobasal degeneration patients showed significant coherence increase between left parietal-right premotor areas. Left hemisphere stroke patients showed significant coherence increases in a right parietofrontal network. The right hemisphere appears to store useable praxis representations in IMA patients with left hemisphere damage. Published by Elsevier Ireland Ltd.
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