Article
Mechanics
X. Lu, X. M. Guo
Summary: In this study, a non-local continuum damage model is developed to analyze the progressive failure of laminated composites. The model incorporates an orthotropic non-local integral strategy with two internal length scales, allowing for accurate predictions of damage evolution. Additionally, an interactive damage transfer scheme is proposed to capture the interaction between matrix cracking and interface delamination. The model demonstrates superior performance over conventional methods in predicting the complex failure mechanisms of composite laminates.
COMPOSITE STRUCTURES
(2022)
Article
Thermodynamics
Changkun Hao, Zezhi Zeng, Bingguo Zhao, Yuping Qian, Weilin Zhuge, Yuqing Wang, Yixiang Shi, Yangjun Zhang
Summary: This study investigates the effect of heat generation management on reducing the temperature gradient in a micro-tubular solid oxide fuel cell. It compares the performance of the cell with tubular separators and flanged separators, showing that both can effectively reduce the temperature gradient, but flanged separators lead to a more uniform temperature profile. The study also proposes a spatial temperature gradient diagram to evaluate the influence of different geometric parameters on the overall performance, revealing that the length of the flanged separator is the primary factor affecting cell performance.
APPLIED THERMAL ENGINEERING
(2022)
Article
Chemistry, Physical
Huacui Wang, Yongjun Pan, Xin Liu, Yangzheng Cao, Yue Liu, Xiaoxi Zhang, Ya Mao, Binghe Liu
Summary: With the rapid development of electric vehicles and electronic devices, the safety issues of lithium-ion batteries have been attracting global attention. By leveraging numerical simulation and stacking tests, the study proposes criteria for the mechanical behaviors of battery component materials to mitigate and postpone internal short circuit. These results provide critical insights into the fundamental mechanistic behaviors during internal short circuits and offer design guidance for the next generation of safe batteries.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
Article
Orthopedics
Gustavo A. Orozco, Paul Bolcos, Ali Mohammadi, Matthew S. Tanaka, Mingrui Yang, Thomas M. Link, Benjamin Ma, Xiaojuan Li, Petri Tanska, Rami K. Korhonen
Summary: This proof-of-concept study developed three-dimensional patient-specific mechanobiological knee joint models to simulate alterations in fixed charged density (FCD) near cartilage lesions during the walking gait. The study suggests mechanisms through which a local FCD loss might occur near cartilage lesions, potentially due to excessive fluid velocity and strain.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2021)
Article
Multidisciplinary Sciences
M. S. Vidya, K. Sunitha, S. Ashok, Deepak Mishra
Summary: This article introduces a stochastic model for inspecting the spread of electrical trees under lightning impulse voltage. By obtaining numerical solutions of Poisson's equation, computing electric field distributions, and evaluating key parameters of damage through histogram plots, the model's efficiency has been verified through statistical analysis.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2022)
Review
Medicine, General & Internal
Lucie Derycke, Stephane Avril, Antoine Millon
Summary: The endovascular technique is widely used in the first line treatment of complex aortic pathologies. The selection of a suitable stent-graft and the operator's experience play a crucial role in its clinical outcome. Numerical simulation provides a digital reproduction of endovascular interventions and can assist practitioners with decision making. This review discusses the basic principles and current literature of using numerical simulation for endovascular management of complex aortic diseases, and highlights its potential to revolutionize everyday clinical applications.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Brian G. Falzon
Summary: The use of lightweight carbon fibre-reinforced polymer composites in transportation vehicles requires ensuring their crashworthiness for passenger safety. Unlike metals, these composites absorb energy through complex damage mechanisms, making the design process more challenging and the physical testing extensive. This paper discusses the progress and challenges in developing a computational capability to simulate the crashworthiness of composites, aiming to reduce the burden of physical testing.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2022)
Article
Construction & Building Technology
Yaohuan Wu, Jun Li
Summary: A three-dimensional nonlinear finite element model was developed to predict the thermal and mechanical behaviors of RC T-beam under different temperature-time curves. Numerical results showed that the temperature and stress of the T-beam varied under different temperature-time curves.
JOURNAL OF BUILDING ENGINEERING
(2022)
Article
Engineering, Biomedical
Stephen L. Alexander, Tusit Weerasooriya
Summary: Incorporating nonlinear mechanism-based and microstructurally-inspired material models in numerical studies can enhance the evaluation of head injury due to externally applied loading. The power-law relationship between localized bone volume fraction (BVF) and modulus (E) provides insights into the mechanical response and fracture of the human skull bone, improving the biofidelity of simulations. Additionally, element-specific failure thresholds derived from microstructurally compatible finite element models enable accurate prediction of localized failure initiation within the human skull, facilitating more realistic simulations at larger length scales.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Engineering, Multidisciplinary
Behrouz Arash, Wibke Exner, Raimund Rolfes
Summary: A finite deformation phase-field fracture model was developed to analyze the thermo-viscoelastic behavior of boehmite nanoparticle/epoxy nanocomposites, considering rate-dependent fracture evolution and the effect of nanoparticle contents and temperature on fracture behavior. The model's predictive capability was validated through comparing numerical results with experimental data, and numerical simulations were performed to study the effect of temperature and deformation rate on the force-displacement response of the nanocomposites in compact-tension tests.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2021)
Article
Mathematics
Yu Feng, Lingfeng Xin, Jianming Hao, Nan Ding, Feng Wang
Summary: Long-span bridges in thunderstorm-prone areas were simulated to study the impact of downburst transient winds. A parameter optimization method and a surrogate model were used to improve the simulation accuracy. The nonstationary turbulent downburst wind was obtained through the combination of Hilbert-based nonstationary fluctuations and CFD-based time-varying trend. The dynamic response of a long-span bridge subjected to the moving downburst was presented, validating the optimized downburst wind field and emphasizing its significant influence on the bridge's aerodynamics and buffeting response.
Article
Chemistry, Physical
Zhong-Hui Shen, Tong-Xiang Tang, Jian Wang, Meng-Jun Zhou, Han-Xing Liu, Long-Qing Chen, Yang Shen, Ce-Wen Nan
Summary: This study investigates the electrical and mechanical response of flexible piezoelectric composites using phase-field simulations. The research finds that good connectivity of fillers can provide load transfer paths and break topological restrictions on polarization dipoles. An interface design strategy is proposed to address the mismatch problem in '3-3' composites, resulting in enhanced overall piezoelectric response.
Article
Construction & Building Technology
Yaning Qiao, Shuyue Zhang, Yaxin Wang, Andrew Dawson, Cameron Wake, Tao Ma
Summary: Flooding has caused significant damage to civil infrastructure globally, particularly roadway pavements. However, quantification of post-flooding pavement damage has only recently received attention, and there is still a knowledge gap regarding how floodwater moves within pavements and how it impacts pavement damage. This study used finite element seepage modeling and laboratory testing to observe floodwater movement and found that pavements exhibit similar post-flooding weakening and recovery behavior. The study also highlighted the importance of understanding the time-depth-damage relationships for post-flooding pavements to estimate economic losses caused by floods.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Engineering, Multidisciplinary
Tim Hageman, Emilio Martinez-Paneda
Summary: We propose a new theoretical and computational framework for modeling electro-chemo-mechanical fracture. The model combines phase field description of fracture with a fully coupled characterization of electrolyte behavior, surface chemical reactions, and stress-assisted diffusion. Unlike other existing methods, our approach accurately captures the results obtained with discrete fracture simulations.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2023)
Article
Computer Science, Interdisciplinary Applications
Seong Pil Byeon, Doo Yong Lee
Summary: This study proposes a method to reduce the computational burden of cutting soft tissue simulation by approximating the gap between model boundaries and finite elements. By introducing partial elements for compensation, the proposed method shows significant advantages in simulation accuracy and computational efficiency.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2021)
Article
Clinical Neurology
N. Yousif, H. Bhatt, P. G. Bain, D. Nandi, B. M. Seemungal
EUROPEAN JOURNAL OF NEUROLOGY
(2016)
Article
Neurosciences
Nada Yousif, Richard Z. Fu, Bilal Abou-El-Ela Bourquin, Vamsee Bhrugubanda, Simon R. Schultz, Barry M. Seemungal
JOURNAL OF NEUROSCIENCE
(2016)
Article
Neurosciences
Nada Yousif, Roman Borisyuk, Nicola Pavese, Dipankar Nandi, Peter Bain
EUROPEAN JOURNAL OF NEUROSCIENCE
(2012)
Article
Neurosciences
Nada Yousif, Joern Diedrichsen
JOURNAL OF NEUROPHYSIOLOGY
(2012)
Article
Biochemical Research Methods
Nada Yousif, Xuguang Liu
JOURNAL OF NEUROSCIENCE METHODS
(2009)
Article
Biochemical Research Methods
Michael Mace, Nada Yousif, Mohammad Naushahi, Khondaker Abdullah-Al-Mamun, Shouyan Wang, Dipankar Nandi, Ravi Vaidyanathan
JOURNAL OF NEUROSCIENCE METHODS
(2014)
Article
Clinical Neurology
Nada Yousif, Nicola Pavese, Mohammad J. Naushahi, Dipankar Nandi, Peter G. Bain
Article
Behavioral Sciences
N. J. Ray, N. Jenkinson, J. Brittain, P. Holland, C. Joint, D. Nandi, P. G. Bain, N. Yousif, A. Green, J. S. Stein, T. Z. Aziz
Article
Neurosciences
N. Yousif, R. Bayford, X. Liu
Article
Clinical Neurology
Nicola Pavese, Yen F. Tai, Nada Yousif, Dipankar Nandi, Peter G. Bain
WORLD NEUROSURGERY
(2020)
Article
Neurosciences
Nada Yousif, Peter G. Bain, Dipankar Nandi, Roman Borisyuk
FRONTIERS IN HUMAN NEUROSCIENCE
(2020)
Article
Mathematics, Applied
James McDonagh, Nunzio Palumbo, Neeraj Cherukunnath, Nikolay Dimov, Nada Yousif
Summary: This research introduces a three-dimensional permanent magnet synchronous motor model developed using FEniCSx, which shows comparable results to the verification model. This method provides the accuracy needed to make electric propulsion systems feasible for large vehicles.
FINITE ELEMENTS IN ANALYSIS AND DESIGN
(2022)
Article
Engineering, Biomedical
Nada Yousif, Carolynne J. Vaizey, Yasuko Maeda
HEALTHCARE TECHNOLOGY LETTERS
(2019)
Article
Clinical Neurology
Ulrike Hammerbeck, Nada Yousif, Damon Hoad, Richard Greenwood, Jorn Diedrichsen, John C. Rothwell
NEUROREHABILITATION AND NEURAL REPAIR
(2017)
Article
Neurosciences
Yang He, Jun Tang, Meng Zhang, Junjie Ying, Dezhi Mu
Summary: This study investigated the protective effects and mechanisms of human placenta derived mesenchymal stem cells (hPMSCs) transplantation in a rat model of hypoxic-ischemic encephalopathy (HIE). The results showed that hPMSCs transplantation reduced apoptosis and improved long-term neurological prognosis. Furthermore, the downregulation of Sema 3A/NRP-1 expression and activation of the PI3K/Akt/mTOR signaling pathway played a key role in the protective effects of hPMSCs.
Article
Neurosciences
Emily L. Isenstein, Edward G. Freedman, Jiayi Xu, Ian A. DeAndrea-Lazarus, John J. Foxe
Summary: This study evaluated electrophysiological discrimination of parametric somatosensory stimuli in healthy young adults to understand how the brain processes the duration of tactile information. The results showed that participants did not electrophysiologically discriminate between 100 and 115 ms, but they exhibited distinct electrophysiological responses when the deviant stimuli were 130, 145, and 160 ms. These findings contribute to a better understanding of tactile sensitivity in different clinical conditions.
Article
Neurosciences
Juliana R. Souza, Ludmila Lima-Silveira, Daniela Accorsi-Mendonca, Benedito H. Machado
Summary: This study demonstrates that A2A receptors play a crucial role in modulating synaptic transmission in the NTS neurons and are required for the enhancement of glutamatergic transmission observed under short-term sustained hypoxia conditions.
Article
Neurosciences
Miki Hashizume, Rina Ito, Rie Suge, Yasushi Hojo, Gen Murakami, Takayuki Murakoshi
Summary: The basolateral amygdaloid complex (BLA) is closely involved in the formation of emotional memories, including both aversive memory and contextual fear memory. Acute sleep deprivation (SD) disrupts the acquisition of tone-associated fear memory in juvenile rats, but has no significant effect on contextual fear memory. Slow network oscillation in the amygdala contributes to the formation of amygdala-dependent fear memory in relation to sleep.
Article
Neurosciences
Qunxian Wang, Shipeng Guo, Dongjie Hu, Xiangjun Dong, Zijun Meng, Yanshuang Jiang, Zijuan Feng, Weihui Zhou, Weihong Song
Summary: GSDME plays a crucial role in the pathogenesis of Alzheimer's disease by regulating the switch from apoptosis to pyroptosis and participating in neuroinflammatory response. Knockdown of GSDME has been shown to improve cognitive impairments, indicating that GSDME could be a therapeutic target for Alzheimer's disease.
