Article
Integrative & Complementary Medicine
Ali Sabbagh Gol, Amir Rezaei Ardani, Seyed Kazem Farahmand, Malihe Dadgarmoghaddam, Vahideh Ghorani, Shima Rezaei, Ali Khorsand
Summary: The study found that the additive effect of acupuncture combined with SSRIs for treating anxiety disorders was significantly better than using SSRIs alone for anti-anxiety therapy. The acupuncture group showed greater improvements in STAI score changes and cortisol level decreases compared to the other groups.
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2021)
Article
Psychiatry
Xiaoting Wu, Mingqi Tu, Nisang Chen, Jiajia Yang, Junyan Jin, Siying Qu, Sangsang Xiong, Zhijian Cao, Maosheng Xu, Shuangyi Pei, Hantong Hu, Yinyan Ge, Jianqiao Fang, Xiaomei Shao
Summary: This study aims to explore the efficacy and cerebral mechanism of intradermal acupuncture for moderate depressive disorder (MDD). Participants will be randomly assigned to a waiting list group, sham intradermal acupuncture group, and active intradermal acupuncture group. Multiple assessment methods will be used to measure the effectiveness after a 6-week intervention and 4-week follow-up. Additionally, selected participants will undergo MRI analysis. If proven effective, intradermal acupuncture may become a routine treatment for MDD.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychiatry
Marjan Shokrani, Sanaz Askari, Negin Eissazade, Seyed Vahid Shariat, Behnam Shariati, Masoomeh Yarahmadi, Mohammadreza Shalbafan
Summary: This study aimed to evaluate the efficacy and safety of agomelatine augmentation of sertraline in the treatment of patients with moderate to severe OCD. The results showed that while agomelatine did not improve OCD symptoms, the combination treatment was safe and effective compared to placebo.
Review
Psychiatry
Andrew G. Guzick, Abigail Candelari, Andrew D. Wiese, Sophie C. Schneider, Wayne K. Goodman, Eric A. Storch
Summary: Studies have shown that obsessive-compulsive symptoms worsened for many patients and individuals during the COVID-19 pandemic, especially for those with contamination-related OCD. However, traditional treatment approaches for OCD are believed to still be effective in managing symptoms despite the pandemic's impact.
CURRENT PSYCHIATRY REPORTS
(2021)
Article
Psychiatry
Christopher Pittenger, Brian P. Brennan, Lorrin Koran, Carol A. Mathews, Gerald Nestadt, Michele Pato, Katharine A. Phillips, Carolyn I. Rodriguez, H. Blair Simpson, Petros Skapinakis, Dan J. Stein, Eric A. Storch
Summary: Obsessive-compulsive disorder affects many people and causes a lot of suffering. Diagnosis is often delayed and treatments often do not follow evidence-based guidelines. Specialty standards have been developed to emphasize the importance of integrating pharmacological treatment with clear diagnosis and evidence-based cognitive behavioral therapy.
PSYCHIATRY RESEARCH
(2021)
Article
Medicine, General & Internal
Jakob Christensen, Betina B. Trabjerg, Yuelian Sun, Julie Werenberg Dreier
Summary: This study examined the association between maternal antidepressant prescription during pregnancy and standardized test scores among Danish schoolchildren. Results showed that children born to mothers filling antidepressant prescriptions during pregnancy had significantly lower math test scores but no significant difference in language test scores compared to children whose mothers did not fill antidepressant prescriptions. The difference in math scores was small and of uncertain clinical importance, suggesting the need to balance the findings against the benefits of treating maternal depression during pregnancy.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Article
Psychiatry
Fredrik Hieronymus, Alexander Lisinski, Elias Eriksson, Soren Dinesen Ostergaard
Summary: This study analyzed patient-level data to assess the relationship between antidepressant side effects and HDRS-17 ratings, finding that some HDRS-17 items are associated with common antidepressant side effects, potentially leading to an underestimation of antidepressant efficacy.
TRANSLATIONAL PSYCHIATRY
(2021)
Article
Clinical Neurology
Lei Zhang, Xuan Liu, Tong Li, Bing Xu, Binfang Fu
Summary: The study found that fluoxetine may enhance cognitive ability in certain domains for patients with VCIND, and increase serum levels of BDNF and VEGF.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Clinical Neurology
Ya-Mei Tzeng, I-Hsun Li, Hui-Han Kao, Jui-Hu Shih, Chin-Bin Yeh, Yi-Hsien Chen, Li-Ting Kao
Summary: This study found that antidepressants can reduce the subsequent risk of psoriasis in patients with major depressive disorder, particularly selective serotonin reuptake inhibitors and low-dose antidepressants have significant protective effects.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Medicine, General & Internal
Jeffry Florian, Rutger van der Schrier, Victoria Gershuny, Michael C. Davis, Celine Wang, Xiaomei Han, Keith Burkhart, Kristin Prentice, Aanchal Shah, Rebecca Racz, Vikram Patel, Murali Matta, Omnia A. Ismaiel, James Weaver, Rodney Boughner, Kevin Ford, Rodney Rouse, Marc Stone, Carlos Sanabria, Albert Dahan, David G. Strauss
Summary: This study aimed to investigate whether combining paroxetine or quetiapine with oxycodone would decrease the ventilatory response to hypercapnia, with findings showing that paroxetine plus oxycodone significantly decreased the ventilatory response on days 1 and 5, while quetiapine plus oxycodone did not have the same effect.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Review
Medicine, General & Internal
Wei Liu, Chang Rao, Qi Zhao, Yuzheng Du, Xi Nan, Zefang Li, Chunsheng Yin
Summary: A meta-analysis will be conducted to evaluate the effectiveness of manual acupuncture therapy on post-stroke depression, with a systematic search on English, Chinese, and Japanese databases. The results will be disseminated through publication in peer-reviewed journals or conference presentations.
Article
Neurosciences
Gwenn S. Smith, Hiroto Kuwabara, Neda F. Gould, Najilla Nassery, Alena Savonenko, Jin Hui Joo, Kristin L. Bigos, Michael Kraut, James Brasic, Daniel P. Holt, Andrew W. Hall, William B. Mathews, Robert F. Dannals, Ayon Nandi, Clifford I. Workman
Summary: Late-life depression (LLD) patients have lower cortical and limbic serotonin transporter (5-HTT) availability compared to controls and show less 5-HTT occupancy by antidepressant medications. Greater regional 5-HTT occupancy by antidepressants is associated with greater improvement in depressive symptoms and visual-spatial memory performance in LLD patients, supporting the hypothesis that serotonin degeneration and variability in 5-HTT occupancy may contribute to heterogeneity in treatment response.
Article
Radiology, Nuclear Medicine & Medical Imaging
Yurong Sun, Xinyi Wang, Shui Tian, Zhilu Chen, Huan Wang, Li Xue, Rui Yan, Zhijian Yao, Qing Lu
Summary: This study investigated the latent pathway of dopamine gene-hierarchical brain network-antidepressant treatment, revealing a close relationship between DRD1 genetic variants and SSRI treatment outcomes as well as brain network connection strength. DRD1 plays a significant role in antidepressant therapy, impacting both treatment response and brain network organization.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Clinical Neurology
Nisang Chen, Xiaoting Wu, Mingqi Tu, Sangsang Xiong, Junyan Jin, Siying Qu, Shuangyi Pei, Jianqiao Fang, Xiaomei Shao
Summary: This article presents a double-blind, randomized controlled trial on the use of intradermal acupuncture (IA) in treating major depressive disorder (MDD) among adolescents. The study compares the effectiveness of IA combined with selective serotonin reuptake inhibitors (SSRIs) to the use of SSRIs alone or sham intradermal acupuncture combined with SSRIs. Various clinical psychiatric scales will be used to assess the efficacy and safety of IA for MDD.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2023)
Article
Dentistry, Oral Surgery & Medicine
Elli Anna Kotsailidi, Catherine Gagnon, Lucy Johnson, Abdul Barmak Basir, Alexandra Tsigarida
Summary: This retrospective study evaluated the association between the use of selective serotonin reuptake inhibitors (SSRIs) and changes in peri-implant marginal bone levels. The results showed a significant correlation between SSRI use and marginal bone loss around dental implants.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jonas Jardim de Paula, Rachel E. R. P. Paiva, Nathalia Gualberto Souza-Silva, Daniela Valadao Rosa, Fabio Luis de Souza Duran, Roney Santos Coimbra, Danielle de Souza Costa, Pedro Robles Dutenhefner, Henrique Soares Dutra Oliveira, Sarah Teixeira Camargos, Herika Martins Mendes Vasconcelos, Nara de Oliveira Carvalho, Juliana Batista da Silva, Marina Bicalho Silveira, Carlos Malamut, Derick Matheus Oliveira, Luiz Carlos Molinari, Danilo Bretas de Oliveira, Jose Nelio Januario, Luciana Costa Silva, Luiz Armando De Marco, Dulciene Maria de Magalhaes Queiroz, Wagner Meira, Geraldo Busatto, Debora Marques Miranda, Marco Aurelio Romano-Silva
Summary: People recovered from mild COVID-19 may experience respiratory and neurological issues, as well as cognitive impairment. A study found that approximately one-quarter of mild COVID-19 individuals exhibited a specific visuoconstructive deficit, which correlated with changes in brain imaging and upregulation of immune markers. These findings suggest that neuroinflammation may contribute to cognitive impairment in a significant portion of the population, highlighting the need for comprehensive assessment and rehabilitation.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychology, Clinical
Marcelo C. Batistuzzo, Karthik Sheshachala, Daniel M. Alschuler, Dianne M. Hezel, Roberto Lewis-Fernandez, Niels T. de Joode, Chris Vriend, Karolina M. Lempert, Madhuri Narayan, Clara Marincowitz, Christine Lochner, Dan J. Stein, Janardhanan C. Narayanaswamy, Odile A. van den Heuvel, Helen Blair Simpson, Melanie Wall
Summary: To improve the consistency of neurocognitive testing across countries, a prospective harmonization approach was used in a global collaborative study. Five tasks were administered to participants from Brazil, India, the Netherlands, South Africa, and the USA. Despite procedural similarity, the Netherlands and India sites showed differences in cognitive performance, indicating potential selection sampling bias. Future studies should follow similar harmonization procedures and consider measuring additional confounding variables.
Article
Psychiatry
Stefania Tognin, Ana Catalan, Matthew J. Kempton, Barnaby Nelson, Patrick McGorry, Anita Riecher-Rossler, Rodrigo Bressan, Neus Barrantes-Vidal, Marie-Odile Krebs, Merete Nordentoft, Stephan Ruhrmann, Gabriele Sachs, Bart P. F. Rutten, Jim van Os, Lieuwe de Haan, Mark van der Gaag, Philip R. McGuire, Lucia Valmaggia
Summary: Research shows that adverse childhood experiences (ACE) can impact educational achievements in individuals at clinical high risk of psychosis (CHR). Specifically, CHR individuals with ACE had lower education levels, employment rates, and estimated IQ compared to healthy controls. Early intervention programs for psychosis should integrate interventions to support the educational and vocational recovery of young CHR individuals, and public health and social interventions to prevent or reduce the impact of ACE are recommended.
EUROPEAN PSYCHIATRY
(2023)
Letter
Biochemistry & Molecular Biology
Jonas J. de Paula, Fabio L. S. Duran, Geraldo Busatto, Debora M. Miranda, Marco A. Romano-Silva
MOLECULAR PSYCHIATRY
(2023)
Article
Psychiatry
Emily J. Hird, Noriyuki Ohmuro, Paul Allen, Peter Moseley, Matthew J. Kempton, Gemma Modinos, Gabriele Sachs, Mark van der Gaag, Lieuwe de Haan, Ary Gadelha, Rodrigo Bressan, Neus Barrantes-Vidal, Stephan Ruhrmann, Ana Catalan, Philip McGuire
Summary: The study found that individuals at clinical high risk for psychosis have a lower sensitivity to hearing speech in noise and uncertainty about the affective valence of this speech, which is associated with adverse clinical outcomes. The findings suggest that the ability to hear speech illusions in noise could be used as a cognitive marker to predict the likelihood of remission or transition to psychosis in individuals at risk.
SCHIZOPHRENIA BULLETIN
(2023)
Article
Psychiatry
Jessica Honorato-Mauer, Gabriela Xavier, Vanessa Kiyomi Ota, Samar Nasser Chehimi, Fernanda Mafra, Cassia Cuoco, Lucas Toshio Ito, Rafaella Ormond, Paula Fontes Asprino, Adrielle Oliveira, Amanda Victoria Gomes Bugiga, Ana Claudia Torrecilhas, Rodrigo Bressan, Gisele Gus Manfro, Euripedes Constantino Miguel, Luis Augusto Rohde, Pedro Mario Pan, Giovanni Abrahao Salum, Renata Pellegrino, Sintia Belangero, Marcos Leite Santoro
Summary: This study analyzed the expression of microRNAs (miRNAs) in serum extracellular vesicles (EVs) from adolescents and found a correlation between miRNA expression and mental health disorders. The results provide support for further research on utilizing EVs miRNAs as biomarkers for mental health disorders.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Biochemistry & Molecular Biology
Willem B. Bruin, Yoshinari Abe, Pino Alonso, Alan Anticevic, Lea L. Backhausen, Srinivas Balachander, Nuria Bargallo, Marcelo C. Batistuzzo, Francesco Benedetti, Sara Bertolin Triquell, Silvia Brem, Federico Calesella, Beatriz Couto, Damiaan A. J. P. Denys, Marco A. N. Echevarria, Goi Khia Eng, Sonia Ferreira, Jamie D. Feusner, Rachael G. Grazioplene, Patricia Gruner, Joyce Y. Guo, Kristen Hagen, Bjarne Hansen, Yoshiyuki Hirano, Marcelo Q. Hoexter, Neda Jahanshad, Fern Jaspers-Fayer, Selina Kasprzak, Minah Kim, Kathrin Koch, Yoo Bin Kwak, Jun Soo Kwon, Luisa Lazaro, Chiang-Shan R. Li, Christine Lochner, Rachel Marsh, Ignacio Martinez-Zalacain, Jose M. Menchon, Pedro S. Moreira, Pedro Morgado, Akiko Nakagawa, Tomohiro Nakao, Janardhanan C. Narayanaswamy, Erika Nurmi, Jose C. Pariente Zorrilla, John Piacentini, Maria Pico-Perez, Fabrizio Piras, Federica Piras, Christopher Pittenger, Janardhan Y. C. Reddy, Daniela Rodriguez-Manrique, Yuki Sakai, Eiji Shimizu, Venkataram Shivakumar, Blair H. Simpson, Carles Soriano-Mas, Nuno M. Sousa, Gianfranco Spalletta, Emily R. Stern, S. Evelyn Stewart, Philip Szeszko, Jinsong Tang, Sophia Thomopoulos, Anders L. Thorsen, Yoshida Tokiko, Hirofumi Tomiyama, Benedetta Vai, Ilya M. Veer, Ganesan Venkatasubramanian, Nora C. Vetter, Chris Vriend, Susanne Walitza, Lea Waller, Zhen Wang, Anri Watanabe, Nicole Wolff, Je-Yeon Yun, Qing Zhao, Wieke A. van Leeuwen, Hein J. F. van Marle, Laurens A. van de Mortel, Anouk van der Straten, Ysbrand D. van der Werf, Paul M. Thompson, Dan J. Stein, Odile A. van den Heuvel, Guido A. van Wingen
Summary: Current knowledge about functional connectivity in obsessive-compulsive disorder (OCD) is based on small-scale studies, limiting the generalizability of results. A mega-analysis of data from 1024 OCD patients and 1028 healthy controls revealed widespread abnormalities in functional connectivity in OCD, including global hypo-connectivity and few hyper-connections mainly with the thalamus. Classification performances based on resting-state connectivity were poor, indicating that it is not an accurate biomarker for identifying individual patients.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychiatry
Matheus Ghossain Barbosa, Viviane Machado, Carolina Ziebold, Tais Moriyama, Rodrigo A. Bressan, Pedro Pan, Luis Augusto Rohde, Euripedes Constantino Miguel, Lais Fonseca, Jim Van Os, Ary Gadelha
Summary: The Brazilian High-Risk Cohort study examined the measurement invariance of the CAPE-positive scale in children and adolescents over a three-year period. The results show that the scale is not invariant over time, indicating the need for further investigation into the factors influencing its results.
SCHIZOPHRENIA RESEARCH
(2023)
Article
Psychiatry
N. C. R. McLaughlin, J. F. Magnotti, G. P. Banks, P. Nanda, M. Q. Hoexter, A. C. Lopes, M. C. Batistuzzo, W. F. Asaad, C. Stewart, D. Paulo, G. Noren, B. D. Greenberg, P. Malloy, S. Salloway, S. Correia, Y. Pathak, J. Sheehan, R. Marsland, A. Gorgulho, A. De Salles, E. C. Miguel, S. A. Rasmussen, S. A. Sheth
Summary: Obsessive-compulsive disorder (OCD) affects 2-3% of the population. Gamma knife capsulotomy (GKC) is an effective treatment option for refractory OCD. Lesions occurring in the ventral and posterior areas of the anterior limb of the internal capsule (ALIC) are associated with the greatest reduction in OCD symptoms.
TRANSLATIONAL PSYCHIATRY
(2023)
Correction
Biochemistry & Molecular Biology
Willem Bruin, Yoshinari Abe, Pino Alonso, Alan Anticevic, Lea Backhausen, Srinivas Balachander, Nuria Bargallo, Marcelo Batistuzzo, Francesco D. Benedetti, Sara G. Bertolin Triquell, Silvia Brem, Federico Y. Calesella, Beatriz Couto, Damiaan A. J. P. Denys, Marco A. N. Echevarria, Goi Khia Q. Eng, Sonia Ferreira, Jamie Feusner, Rachael Grazioplene, Patricia Gruner, Joyce Guo, Kristen Hagen, Bjarne Hansen, Yoshiyuki Hirano, Marcelo Hoexter, Neda Jahanshad, Fern Jaspers-Fayer, Selina Kasprzak, Minah M. Kim, Kathrin S. Koch, Yoo Bin Kwak, Jun Soo Kwon, Luisa Lazaro, Chiang-Shan R. C. Li, Christine L. Lochner, Rachel Marsh, Ignacio Martinez-Zalacain, Jose Menchon, Pedro Moreira, Pedro Morgado, Akiko Nakagawa, Tomohiro Nakao, Janardhanan Narayanaswamy, Erika Nurmi, Jose C. Pariente Zorrilla, John Piacentini, Maria H. Pico-Perez, Fabrizio Piras, Federica Piras, Christopher Pittenger, Janardhan Y. C. R. Reddy, Daniela Rodriguez-Manrique, Yuki R. Sakai, Eiji Shimizu, Venkataram I. Shivakumar, Blair L. Simpson, Carles Soriano-Mas, Nuno Sousa, Gianfranco Spalletta, Emily M. Stern, S. Evelyn Stewart, Philip C. Szeszko, Jinsong Tang, Sophia Thomopoulos, Anders Thorsen, Tokiko Yoshida, Hirofumi Tomiyama, Benedetta Vai, Ilya Veer, Ganesan Venkatasubramanian, Nora A. Vetter, Chris Vriend, Susanne A. Walitza, Lea Waller, Zhen D. Wang, Anri Watanabe, Nicole Wolff, Je-Yeon Yun, Qing Zhao, Wieke van Leeuwen, Hein J. F. van Marle, Laurens van de Mortel, Anouk van der Straten, Ysbrand van der Werf, Honami C. Arai, Irene Bollettini, Rosa Calvo Escalona, Ana Coelho, Federica Colombo, Leila Darwich, Martine Fontaine, Toshikazu Ikuta, Jonathan Ipser, Asier Juaneda-Segui, Hitomi Kitagawa, Gerd Kvale, Mafalda R. Machado-Sousa, Astrid Morer, Takashi G. Nakamae, Jin J. Narumoto, Joseph O'Neill, Sho A. Okawa, Eva Real, Veit A. Roessner, Joao Sato, Cinto D. Segalas, Roseli A. Shavitt, Dick A. Veltman, Kei M. Yamada, Paul J. Thompson, Dan A. Stein, Odile A. van den Heuvel, Guido van Wingen
MOLECULAR PSYCHIATRY
(2023)
Article
Psychiatry
Ana Paula Aguiar, Angel Olider Rojas Vistorte, Henrique Teruo Akiba, Paula Oliveira, Deise Palermo Puertas Ruiz, Ary Gadelha, Rodrigo Affonseca Bressan, Pedro Mario Pan
Summary: Methods to prospectively identify individuals at high risk of developing psychosis have been proposed, and this study translated and adapted two screening tools (PQ-16 and PRIME-Screen) into Brazilian Portuguese. After translation and cross-cultural adaptation, these new instruments can be used to screen Brazilian Portuguese-speaking patients who are at risk of psychosis in primary care.
TRENDS IN PSYCHIATRY AND PSYCHOTHERAPY
(2023)
Correction
Psychiatry
David Mongan, Melanie Focking, Colm Healy, Subash Raj Susai, Meike Heurich, Kieran Wynne, Barnaby Nelson, Patrick D. McGorry, Paul Amminger, Merete Nordentoft, Marie-Odile Krebs, Anita Riecher-Rossler, Rodrigo A. Bressan, Neus Barrantes-Vidal, Stefan Borgwardt, Stephan Ruhrmann, Gabriele Sachs, Christos Pantelis, Mark van der Gaag, Lieuwe de Haan, Lucia Valmaggia, Thomas A. Pollak, Matthew J. Kempton, Bart P. F. Rutten, Robert Whelan, Mary Cannon, Stan Zammit, Gerard Cagney, David R. Cotter, Philip McGuire
Article
Substance Abuse
Renata Faro Guerra, Ilza Rosa Batista, Hyoun S. Kim, Marcelo Queiroz Hoexter, Ming Chi Shih, Rodrigo Affonseca Bressan, Hermano Tavares
Summary: The aim of this research was to investigate the association between dopamine transporter (DAT) density in the ventral striatum and gambling disorder (GD). The results suggest that DAT density in the striatum is associated with recent gambling activity and gambling expectation.
JOURNAL OF GAMBLING STUDIES
(2023)