期刊
NEUROPSYCHOLOGY REVIEW
卷 18, 期 1, 页码 91-102出版社
SPRINGER
DOI: 10.1007/s11065-008-9056-z
关键词
Frontotemporal dementia; FTD; neuropsychology; differential diagnosis; executive function
资金
- NIA NIH HHS [R01 AG022983, R01 AG022983-05, P50 AG023501, P01 AG017586] Funding Source: Medline
Frontotemporal lobar degeneration (FTLD) represent a constellation of disorders that may be overlooked or misdiagnosed, despite being fairly common presenile neurodegenerative diseases. Although the cognitive disorder can be difficult to document, particularly early in the dementia course, neuropsychological evaluation can assist in the diagnosis. Neuropsychologists are in an excellent position to draw from related disciplines like personality theory and social psychology to better assess the types of changes that characterize the prodromal and early phases of the disease. This review summarizes the current state of the field in the diagnosis of FTLD and discusses the emerging role of neuropsychology in elucidating the brain organization of complex processes including empathy, behavioral control and inhibition, reward systems, appetitive behaviors, emotional regulation, and goal-orientation. As this review underscores, frontotemporal dementia remains a powerful model for studying brain-behavior relationships.
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