4.5 Article

An online version of the Mooney Face Test: phenotypic and genetic associations

期刊

NEUROPSYCHOLOGIA
卷 63, 期 -, 页码 19-25

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neuropsychologia.2014.08.011

关键词

Face perception; Mooney Face Test; Closure; Gestalt perception; Individual differences; Genome-wide association study (GWAS); RAPGEF5; rs1522280

资金

  1. Gatsby Charitable Foundation [GAT2903]

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The Mooney Face Test is a widely used test of face perception, but was originally designed to be administered by personal interview. We have developed a three-alternative forced-choice version for online testing. We tested 397 healthy adults between the ages of 18 and 42 (M=24 years). There was a wide range of performance (64-100% correct; M=89.6%). We observed a significant sex difference favoring males (.31 standard deviation; p =.004). In addition, independently of sex, higher 2D:4D digit ratios were significantly associated with higher scores (rho=.14, p=.006). A genome-wide association study (GWAS) for a subset of 370 participants identified an association between Mooney performance and a polymorphism in the RAPGEF5 gene (rs1522280; p=9.68 x 10(-8)). This association survives a permutation test (p=.031). (C) 2014 Elsevier Ltd. All rights reserved.

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