Article
Multidisciplinary Sciences
Mikael Lundqvist, Scott L. Brincat, Jonas Rose, Melissa R. Warden, Timothy J. Buschman, Earl K. Miller, Pawel Herman
Summary: Working memory is achieved through interactions between beta and gamma oscillations, which allow the spatial flow of item-specific activity across the network. This spatial flow is independent of the detailed recurrent connectivity supporting the item-specific activity, and control-related information is stored in the spatial activity. Analysis of local field potentials and neuronal spiking confirms these predictions. Spatial computing can facilitate generalization and zero-shot learning by utilizing spatial component as an additional information encoding dimension.
NATURE COMMUNICATIONS
(2023)
Article
Neurosciences
Youngsun T. Cho, Flora Moujaes, Charles H. Schleifer, Martina Starc, Jie Lisa Ji, Nicole Santamauro, Brendan Adkinson, Antonija Kolobaric, Morgan Flynn, John H. Krystal, John D. Murray, Grega Repovs, Alan Anticevic
Summary: This study investigated how reward and loss impact spatial working memory precision and neural circuits in human subjects. The results showed that both reward and loss improved spatial working memory precision, with specific regions like precentral sulcus and intraparietal sulcus having increased BOLD signal related to better working memory precision. Conversely, areas straddling executive networks displayed decreased BOLD signal during incentivized working memory.
Article
Biochemistry & Molecular Biology
Miral Abdalaziz, Zach Redding, Ian C. Fiebelkorn
Summary: Selective attention is characterized by alternating states that isolate function-specific neural activity in time. We tested the hypothesis that rhythmic temporal coordination can also prevent representational conflicts during working memory. The results support the idea that rhythmic temporal coordination is a general mechanism for preventing conflicts and inform models of working memory organization.
Article
Neurosciences
Tiam Hosseinian, Fatemeh Yavari, Min-Fang Kuo, Michael A. Nitsche, Asif Jamil
Summary: The study developed a new technique to induce and stabilize theta oscillations in the human brain, and found that this technique enhances cognitive processing through testing working memory. The results demonstrate technological advancement in brain stimulation methods and validate the causal link between theta activity and cognitive behavior.
Article
Multidisciplinary Sciences
Jung Won Bae, Huijeong Jeong, Young Ju Yoon, Chan Mee Bae, Hyeonsu Lee, Se-Bum Paik, Min Whan Jung
Summary: In the prefrontal cortex, intratelencephalic and pyramidal tract neurons have different roles in maintaining working memory and tracking the passage of time.
NATURE COMMUNICATIONS
(2021)
Article
Behavioral Sciences
Yali Feng, Jack Jiaqi Zhang, Jiaqi Zhu, Xiaobing Tan, Sanyue Huang, Zhongfei Bai, Ying Yin
Summary: This study aimed to investigate the effects of intermittent theta burst stimulation (iTBS) on working memory performance in healthy adults, specifically focusing on the left dorsolateral prefrontal cortex (LDLPFC) and right dorsolateral prefrontal cortex (RDLPFC). The results showed significant time effects on overall accuracy in both 2-back and 3-back tasks, as well as on total reaction time in 3-back tasks. However, there were no significant interaction effects between time and group.
BEHAVIOURAL BRAIN RESEARCH
(2023)
Review
Biology
Jennifer C. Robinson, Mark P. Brandon
Summary: The passage discusses the connection between envisioning the future and remembering the past, explaining the roles of the prefrontal cortex and hippocampus in memory and future planning, as well as how brain regions support the temporal organization of information.
Article
Neurosciences
Robert Kim, Terrence J. Sejnowski
Summary: By analyzing computational models and neural data, the authors demonstrate that inhibitory-to-inhibitory signaling is crucial for maintaining stable temporal dynamics and working memory in the primate prefrontal cortex.
NATURE NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Chenguang Zhao, Dongwei Li, Yuanjun Kong, Hongyu Liu, Yiqing Hu, Haijing Niu, Ole Jensen, Xiaoli Li, Hanli Liu, Yan Song
Summary: This study found that transcranial photobiomodulation (tPBM) at a wavelength of 1064 nm applied to the right prefrontal cortex (PFC) can improve visual working memory capacity and increase occipitoparietal contralateral delay activity (CDA). The CDA set-size effect mediates the effect between 1064-nm tPBM and subsequent working memory capacity.
Article
Behavioral Sciences
Liping Pan, Dandan Guo, Jiajing Wang, Yuhan Hao, Lulin Zhang, Xiao Qin, Yijun Song
Summary: Patients with temporal lobe epilepsy show decreased theta power during the encoding phase of working memory, which is associated with reduced task accuracy; altered theta power in the frontal region during the encoding phase is related to longer reaction time.
EPILEPSY & BEHAVIOR
(2021)
Article
Neurosciences
Maitreyee Kulkarni, Thomas J. Covey
Summary: This study used event-related potential source localization method to investigate the effect of working memory (WM) training on neural activity. The results showed that the enhancement of activity in the medial orbitofrontal cortex and cingulate cortex within 200-350 milliseconds after stimulus onset was associated with the effectiveness of WM training, playing an important role in the enhancement of WM performance along the spatial and temporal dimensions.
Article
Neurosciences
Sihai Li, Christos Constantinidis, Xue-Lian Qi
Summary: The study investigated the roles of the dorsolateral prefrontal cortex and posterior parietal cortex in working memory, finding that neuronal activity can predict categorical judgments of information and deviations in firing rates reflect the contents of working memory.
Article
Biochemistry & Molecular Biology
Yang Yang, Sang-Min Lee, Fumiaki Imamura, Krishne Gowda, Shantu Amin, Richard B. Mailman
Summary: This study compared two different D-1 agonists and found that 2-methyldihydrexidine was more effective in enhancing cognition compared to CY208,243, based on its impact on neural activity and cognitive performance.
MOLECULAR PSYCHIATRY
(2021)
Article
Neurosciences
Liping Pan, Jiajing Wang, Wenjuan Wu, Yunfan Wang, Yujing Zhu, Yijun Song
Summary: This study investigated the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on working memory (WM) in refractory temporal lobe epilepsy (rTLE) patients and its underlying mechanisms. The results showed that after 20 weeks of taVNS, the reaction time of working memory was significantly reduced, and the power spectral density of the theta frequency band in the frontal midline also decreased significantly.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Neurosciences
Minghong Su, Kejia Hu, Wei Liu, Yunhao Wu, Tao Wang, Chunyan Cao, Bomin Sun, Shikun Zhan, Zheng Ye
Summary: This study investigated the interaction between the dorsolateral prefrontal cortex (DLPFC) and the hippocampus in the online processing of sequential information using stereoelectroencephalography (SEEG). The results showed that increases in thinking time and recall errors were associated with theta power increases in the hippocampus and the DLPFC. Theta phase coherences between the DLPFC and hippocampus were enhanced for ordering, and the DLPFC->hippocampus influence in the theta band was selectively enhanced for more precisely memorized lines. This suggests that theta oscillations may play a role in supporting the interaction between the DLPFC and hippocampus during the online processing of sequential information.
NEUROSCIENCE BULLETIN
(2023)