Article
Neurosciences
Youngsun T. Cho, Flora Moujaes, Charles H. Schleifer, Martina Starc, Jie Lisa Ji, Nicole Santamauro, Brendan Adkinson, Antonija Kolobaric, Morgan Flynn, John H. Krystal, John D. Murray, Grega Repovs, Alan Anticevic
Summary: This study investigated how reward and loss impact spatial working memory precision and neural circuits in human subjects. The results showed that both reward and loss improved spatial working memory precision, with specific regions like precentral sulcus and intraparietal sulcus having increased BOLD signal related to better working memory precision. Conversely, areas straddling executive networks displayed decreased BOLD signal during incentivized working memory.
Article
Multidisciplinary Sciences
David Mark Watson, Michael A. Akeroyd, Neil W. Roach, Ben S. Webb
Summary: The ventriloquism aftereffect involves recalibration of auditory space in response to spatial disparities between visual and auditory stimuli in dynamic multisensory environments. Previous research has shown that this phenomenon is driven by multiple recalibration mechanisms operating on different timescales, utilizing both eye- and head-centered spatial reference frames. However, there is no clear interaction between spatial reference frames and adaptation duration across all timescales.
Article
Multidisciplinary Sciences
Caitlin S. Mallory, Kiah Hardcastle, Malcolm G. Campbell, Alexander Attinger, Isabel I. C. Low, Jennifer L. Raymond, Lisa M. Giocomo
Summary: Neural circuits in the medial temporal lobe construct a map-like representation of space that supports navigation by integrating multiple sensory cues and cues related to the individual's movement through the environment. The medial entorhinal cortex (MEC) encodes three-dimensional head movement, eye position, and velocity, alongside other self-motion signals in individual neurons, such as body position, running speed, and azimuthal head direction.
NATURE COMMUNICATIONS
(2021)
Article
Multidisciplinary Sciences
Gema Martin-Ordas
Summary: Spatial cognitive abilities are crucial for foraging animals, and encoding the location of an object in relation to another object is essential for successful foraging. Bees predominantly use egocentric information to encode spatial information, but they exhibit an allocentric strategy in the context of relational similarity, suggesting that egocentric representations may not be evolutionary ancestral.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Nicola Domenici, Valentina Sanguineti, Pietro Morerio, Claudio Campus, Alessio Del Bue, Monica Gori, Vittorio Murino
Summary: Our brain combines sensory information to build coherent representations of the environment. We developed a neural architecture replicating humans' ability to use audiovisual spatial representations. Our model closely replicated human perceptual behavior and can be used to model multisensory integration processes in experimental and rehabilitation environments.
Article
Neurosciences
Bo Zhang, Fan Wang, Qi Zhang, Yuji Naya
Summary: Our mental representation of egocentric space is influenced by the disproportionate sensory perception of the body. Previous studies have focused on the neural architecture for egocentric representations within the visual field. However, the space representation underlying the body is still unclear. This study used fMRI and MEG to investigate the spatial representation of targets relative to the body and found that the frontoparietal network is more involved in representing left/right targets, while the MTL-parietal network is more involved in retrieving targets behind the participant. MEG data also showed an earlier activation of the MTL-parietal network during target retrieval.
Article
Neurosciences
Shintaro Funahashi, Binbin Gao, Kazuyoshi Takeda, Yumiko Watanabe, Jinglong Wu, Tianyi Yan
Summary: Performing working memory tasks require maintenance and transformation of information. Delay-period activity recorded from prefrontal neurons showed a gradual change from sensory to motor information during the delay period. Individual prefrontal neurons were found to encode and adjust cue directions by referencing retinotopic or saccade-based coordinate frames. Manipulating the reference frame allows for the transformation of visual-to-motor information.
Article
Clinical Neurology
Tais Regina da Silva, Helio Rubens de Carvalho Nunes, Lais Geronutti Martins, Rafael Dalle Molle da Costa, Juli Thomaz de Souza, Fernanda Cristina Winckler, Lorena Cristina Alvarez Sartor, Gabriel Pinheiro Modolo, Natalia Cristina Ferreira, Josiela Cristina da Silva Rodrigues, Rafael Kanda, Marcelo Ortolani Fogarolli, Guilherme Ferreira Borges, Gabriela Rizzo Soares Rizzatti, Priscila Watson Ribeiro, Diandra B. Favoretto, Luan R. Aguiar dos Santos, Silmeia Garcia Zanati Bazan, Luiz Eduardo Betting, Leticia Claudia de Oliveira Antunes, Vitor Mendes Pereira, Taiza G. S. Edwards, Octavio Marques Pontes-Neto, Adriana Bastos Conforto, Rodrigo Bazan, Gustavo Jose Luvizutto
Summary: This study aimed to examine the effects of physical therapy after anodal and cathodal transcranial direct current stimulation (A-tDCS and C-tDCS, respectively) to improve visuospatial and functional impairments in individuals with USN after stroke. Results showed that A-tDCS led to greater improvement in BIT-C after intervention compared to sham, while no significant differences were observed in secondary outcomes between groups.
ANNALS OF NEUROLOGY
(2022)
Article
Biology
Hyuk-June Moon, Baptiste Gauthier, Hyeong-Dong Park, Nathan Faivre, Olaf Blanke
Summary: This study found that manipulating bodily signals to modulate self-centered processing can improve spatial navigation performance and decrease grid cell-like expression in the entorhinal cortex. Furthermore, this decrease in expression was associated with an increase in activity in the retrosplenial cortex and correlated with participants' navigation performance.
COMMUNICATIONS BIOLOGY
(2022)
Article
Neurosciences
Ford Burles, Giuseppe Iaria
Summary: This study used functional magnetic resonance imaging (fMRI) to investigate the impact of long-duration spaceflight on the neural processes supporting astronauts' spatial orientation skills. The findings showed a general reduction in neural activity in spatial-processing brain regions after spaceflight, particularly in the precuneus region. These results highlight the importance of developing strategies or procedures to mitigate the detrimental effects of spaceflight on spatial cognition in future long-distance missions.
Article
Psychology, Experimental
Raffaele Tucciarelli, Elisa R. R. Ferre, Elena Amoruso, Elena Azanon, Matthew R. R. Longo
Summary: When reproducing the remembered location of dots within a circle, judgments are biased towards the imaginary center of quadrants formed by imaginary vertical and horizontal axes. This bias can be attributed to the heightened precision in the visual system for these orientations in a retinotopic reference frame, or to the internal representation of gravity. By dissociating reference frames defined by the retina and by gravity, the study found that spatial categories are determined by a combination of both gravitational and retinal factors.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2023)
Article
Neurosciences
Jinhui Li, Ruibin Zhang, Siqi Liu, Qunjun Liang, Senning Zheng, Xianyou He, Ruiwang Huang
Summary: Humans use different spatial reference frames for navigation with specific brain regions being activated. Environmental space shows stronger activation in certain brain regions compared to vista space, and allocentric reference frame also displays stronger activation in some areas.
Article
Psychology, Mathematical
Holger Schultheis
Summary: The study found that alignment effects in spatial memory primarily stem from organization along reference directions rather than relation encoding. Data from both tasks indicated that only a single direction is encoded in memory.
PSYCHONOMIC BULLETIN & REVIEW
(2021)
Article
Behavioral Sciences
Julien Poitreau, Manon Buttet, Christine Manrique, Bruno Poucet, Francesca Sargolini, Etienne Save
Summary: The study indicates that the medial entorhinal cortex (MEC) is necessary for place navigation using a global reference frame, while the lateral entorhinal cortex (LEC) and MEC are not required for navigation using a local reference frame. The identity of objects does not affect the accuracy of place navigation.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Neurosciences
Hannah Sheahan, Fabrice Luyckx, Stephanie Nelli, Clemens Teupe, Christopher Summerfield
Summary: The study found that both human brains and recurrent neural networks developed similar neural "number lines" for each context when performing a magnitude comparison task, facilitating the generalization of relational concepts. Neural normalization plays an important role in supporting the transfer of abstract relational knowledge in humans and machine learning systems.
Article
Neurosciences
Eric Avila, Kaushik J. Lakshminarasimhan, Gregory C. DeAngelis, Dora E. Angelaki
Article
Neurosciences
Ramon Nogueira, Nicole E. Peltier, Akiyuki Anzai, Gregory C. DeAngelis, Julio Martinez-Trujillo, Ruben Moreno-Bote
JOURNAL OF NEUROSCIENCE
(2020)
Article
Neurosciences
Shaun L. Cloherty, Jacob L. Yates, Dina Graf, Gregory C. DeAngelis, Jude F. Mitchell
Article
Neurosciences
Kaushik J. Lakshminarasimhan, Eric Avila, Erin Neyhart, Gregory C. DeAngelis, Xaq Pitkow, Dora E. Angelaki
Article
Neurosciences
Ryo Sasaki, Akiyuki Anzai, Dora E. Angelaki, Gregory C. DeAngelis
NATURE NEUROSCIENCE
(2020)
Article
Ophthalmology
Nicole E. Peltier, Dora E. Angelaki, Gregory C. DeAngelis
Article
Neurosciences
Aihua Chen, Fu Zeng, Gregory C. DeAngelis, Dora E. Angelaki
Summary: The activity in the parieto-insular vestibular cortex (PIVC) reflects a dynamically changing combination of sensory and choice signals, with a more balanced representation compared to other regions. Interestingly, there is a negative correlation between heading and choice signals in PIVC during the middle portion of the stimulus epoch.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Zhe-Xin Xu, Gregory C. DeAngelis
Summary: There are two sources of retinal image motion: objects moving in the world and observer movement. Neurons in the middle temporal (MT) area combine eye velocity and retinal velocity, potentially through a partial coordinate transformation or a multiplicative gain interaction, to compute head-centered object motion and depth information.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Adam Zaidel, Jean Laurens, Gregory C. DeAngelis, Dora E. Angelaki
Summary: This study found that adult rhesus macaques show little neural plasticity in the lower-level multisensory cortical area MSTd, but exhibit neural plasticity in the higher-level multisensory area VIP. The systematic shifts in VIP tuning curves were observed, reflecting the decision-related component of the population response. The results demonstrate neuronal calibration in single sessions, laying the foundation for understanding multisensory neural plasticity in maintaining accuracy for sensorimotor tasks.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Biology
HyungGoo R. Kim, Dora E. Angelaki, Gregory C. DeAngelis
Summary: The detection of object motion in a scene during self-motion is not well understood. Neurons in the macaque middle temporal area have been found to have incongruent depth tuning for binocular disparity and motion parallax cues, and they play a role in predicting perceptual decisions during the detection of moving objects.
Article
Multidisciplinary Sciences
Ranran L. French, Gregory C. DeAngelis
Summary: An important function of the visual system is to represent 3D scene structure from 2D images. Motion parallax provides depth information, but object motion relative to the scene can complicate depth computation. Our study found that scene-relative object motion can confound depth perception.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
Grace F. DiRisio, Yongsoo Ra, Yinghui Qiu, Akiyuki Anzai, Gregory C. DeAngelis
Summary: Smooth eye movements are essential for natural visual processes, and they can be guided by both visual cues and extraretinal signals. This study focuses on how the brain processes and integrates these signals during smooth pursuit eye movements. The researchers investigate the responses of neurons in the MSTd area of rhesus monkeys and find that most neurons have preferences for the direction of eye rotation based on both visual and extraretinal signals. This suggests that area MSTd plays a crucial role in integrating these signals and representing the velocity of smooth eye movements.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Adam D. Danz, Dora E. Angelaki, Gregory C. DeAngelis
Review
Physiology
Ranran L. French, Gregory C. DeAngelis
CURRENT OPINION IN PHYSIOLOGY
(2020)
Article
Neurosciences
L. Caitlin Elmore, Ari Rosenberg, Gregory C. DeAngelis, Dora E. Angelaki