4.3 Article

Percutaneous Peripheral Nerve Stimulation for Chronic Pain in Subacromial Impingement Syndrome: A Case Series

期刊

NEUROMODULATION
卷 17, 期 8, 页码 771-776

出版社

WILEY
DOI: 10.1111/ner.12152

关键词

Chronic pain; electrode placement; nonmalignant pain; percutaneous nerve stimulation; peripheral nerve stimulation

资金

  1. Case Western Reserve University/Cleveland Clinic CTSA from the National Center for Research Resources (NCRR), a component of the National Institutes of Health [UL1 RR024989]
  2. NCRR/NIH [UL1 RR024989, M01 RR00080]
  3. SPR Therapeutics, LLC

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ObjectiveThe objective of this study was to determine the effect of peripheral nerve stimulation (PNS) on pain reduction for those with refractory subacromial impingement syndrome (SIS) and to evaluate the association with reduced disability, impairment, and safety. Our hypotheses are that PNS will be associated with a reduction in pain, impairment and disability, and improvement in quality of life while demonstrating safety. Material and MethodsAdults with shoulder pain of at least six months duration were recruited for a three-week treatment of percutaneous PNS applied through a percutaneous electrode to the axillary motor points of the deltoid muscle. Subjects were followed for 12 weeks after treatment. The primary outcome was the worst pain in the last week, and secondary outcomes included pain interference, the Disabilities of the Arm, Shoulder, and Hand questionnaire, shoulder abduction range of motion, and safety. Analysis was with a linear mixed model. ResultsTen subjects were recruited. Longitudinal analysis demonstrated significant reduction in pain relative to baseline (F(1, 66) = 12.9, p < 0.01). After correcting for multiple comparisons, there were significant reductions at explantation and all follow-up time points when compared with baseline. There were also significant improvements in pain interference (F(1,65) = 15.0, p < 0.01), the Disabilities of the Arm, Shoulder, and Hand questionnaire (F(1,35) = 7.0, p = 0.01), and shoulder abduction range of motion (F(1,35) = 6.3, p = 0.02). ConclusionIntramuscular PNS for chronic shoulder pain due to SIS is a safe treatment associated with pain reduction, lower pain interference with activities of daily living, reduced disability, and improved shoulder abduction. Pain reduction is maintained for at least 12 weeks after treatment.

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