Is it time to revisit the classification guidelines for primary progressive aphasia?

Hair-splitting details of syndromic classification can hardly be expected to attract much attention. As in all areas of science, however, sound nosology and uniform nomenclature are important for progress in neurology. This is particularly true for the neurodegenerative syndromes, including primary progressive aphasia (PPA), where heterogeneity of phenotype and cellular pathology has defied attempts to coherent clinicopathologic correlations.