Review
Neurosciences
Nicolas Hernandez Norager, Markus Harboe Olsen, Sarah Hornshoej Pedersen, Casper Schwartz Riedel, Marek Czosnyka, Marianne Juhler
Summary: This study establishes position-dependent reference values for intracranial pressure and lumbar cerebrospinal fluid pressure for the first time. Clinically applicable reference values for normal lumbar cerebrospinal fluid pressure have been established, consistent with previously used reference values. For intracranial pressure, the study emphasizes the scarcity of normal pressure measures and the need for further research in this area.
FLUIDS AND BARRIERS OF THE CNS
(2021)
Review
Engineering, Biomedical
Seifollah Gholampour, Amber Nguyen, Saad Chaudry
Summary: This study aims to explore the correlations between intracranial compliance (ICC), resistance to cerebrospinal fluid (CSF)-outflow (Rout), pressure-volume index (PVI), and intracranial pressure (ICP) characteristics in hydrocephalus patients. The results show significant correlations between ICC and Rout with ICP characteristics. PVI also correlates significantly with Evan's ratio, inverse cella media, and ventricular score.
Article
Neurosciences
Marijan Klarica, Milan Rados, Gorislav Erceg, Ivana Jurjevic, Antonio Petosic, Zdravko Virag, Darko Oreskovic
Summary: The study found that changes in spinal cerebrospinal fluid volume significantly affect intracranial cerebrospinal fluid pressure, but regardless of whether the volume is increased or decreased, the hydrostatic pressure difference between the measuring sites remains constant.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Obstetrics & Gynecology
Swathi Gunti, Vrinda Nair, Prakash Kannan Loganathan
Summary: This study aimed to report the reference range of cerebrospinal fluid (CSF) parameters in both preterm and term infants for the diagnosis of neonatal bacterial meningitis. The results showed that the CSF white blood cell count was similar between preterm and term infants without meningitis, while the CSF protein content was higher in preterm infants and infants in the first seven days of life. The presence of any CSF red blood cells influenced CSF parameters.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Veterinary Sciences
Alexandre Triguinho, Ana Patricia Fontes-Sousa, Jose Pimenta, Mario Cotovio
Summary: This study aimed to establish electrocardiographic reference values for healthy Lusitano horses, with 82 clinically healthy animals being evaluated. The results showed a median heart rate of 39 beats per minute, with predominantly bifid P waves and various forms of the QRS complex. These findings highlight the importance of establishing breed-specific electrocardiographic reference values for athletic horses.
VETERINARY SCIENCES
(2023)
Article
Clinical Neurology
Chao Zhang, Si-Yu Long, Wen-Dong You, Xu-Xu Xu, Guo-Yi Gao, Xiao-Feng Yang
Summary: This study evaluated the correlation between ICP wave amplitude, mean ICP level, and resistance to CSF outflow in predicting the outcome of patients with post-traumatic hydrocephalus selected for shunting. The results showed that combining ICP wave amplitude and CSF outflow resistance is a better predictor for a good outcome to shunting. These findings help in predicting the probability of a desirable recovery level and optimizing treatment plans for ineffective or unnecessary shunting.
FRONTIERS IN NEUROLOGY
(2022)
Article
Neurosciences
Daniel Omileke, Steven W. Bothwell, Debbie Pepperall, Daniel J. Beard, Kirsten Coupland, Adjanie Patabendige, Neil J. Spratt
Summary: The study suggests that hypothermia treatment can prevent ICP elevation, reduce infarct volume, and may be related to CSF outflow resistance post-stroke. Further research is needed to clarify the mechanisms behind ICP elevation and hypothermia treatment.
Article
Endocrinology & Metabolism
Desiree Lopez-Gonzalez, Jonathan C. Wells, Mario Cortina-Borja, Mary Fewtrell, Armando Partida-Gaytan, Patricia Clark
Summary: This study provides reference values for relevant bone health variables for healthy Mexican children and adolescents, aiding in more precise assessment of bone health. The reference data include percentiles and gender-specific values. Additionally, height-relative and Tanner-stage reference values are provided.
Article
Agriculture, Dairy & Animal Science
Daniela Proverbio, Roberta Perego, Luciana Baggiani, Giuliano Ravasio, Daniela Giambellini, Eva Spada
Summary: The tiger (Panthera tigris) is the largest wild cat, but due to poaching and hunting of their prey, global tiger populations have drastically decreased and are critically endangered. Conducting health monitoring and blood testing can provide valuable information for conservation strategies for tigers.
Article
Sport Sciences
Jonathan Wagner, Raphael Knaier, Denis Infanger, Karsten Konigstein, Christopher Klenk, Justin Carrard, Henner Hanssen, Timo Hinrichs, Douglas Seals, Arno Schmidt-Trucksass
Summary: This study aimed to provide CPET reference values for a healthy European cohort across different age groups, finding that VO2peak values decrease with age and differ from other studies. The study also found a positive association between vigorous-intensity physical activity and VO2peak and other CPET parameters.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Public, Environmental & Occupational Health
Chao Ji, Yang Xia, Huixu Dai, Zhiying Zhao, Tiancong Liu, Shuhui Tong, Xiaohang Zhang, Yuhong Zhao
Summary: This study aimed to determine age- and sex-specific reference values of PEF in the middle-aged and elderly Chinese population. PEF was found to decrease with age and be higher in men than in women. Factors such as height, weight, handgrip strength, and residence in rural areas were positively associated with PEF.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Ali Ahmed, Muhammad Uzair UlHaq, Zartasha Mustansar, Arslan Shaukat, Lee Margetts
Summary: This study investigates deformation and pressure within a tumor-based brain using finite-element modeling. Results indicate that as the tumor region increases, deformation pattern changes extensively and spreads throughout the brain volume, while ICP pressures increase substantially but remain under normal values.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Clinical Neurology
So Youn Choi, Minjung Seong, Eung Yeop Kim, Michelle Sojung Youn, Soohyun Cho, Hyemin Jang, Mi Ji Lee
Summary: The study found that epidural blood patch showed significant treatment response in patients with suspected spontaneous intracranial hypotension, even when brain and spinal imaging results were negative.
Article
Urology & Nephrology
Hyung Joon Kim, Marne M. Louters, Julie J. Dau, Timothy L. Hall, Khurshid R. Ghani, William W. Roberts
Summary: The study aimed to measure the outflow resistance of different drainage devices used during ureteroscopy. The results can guide the selection of the appropriate type and size of drainage device to ensure safe renal pelvis pressure.
WORLD JOURNAL OF UROLOGY
(2023)
Article
Nutrition & Dietetics
Lopez-Gonzalez Desiree, Jonathan Wells, Partida-Gaytan Armando, Cortina-Borja Mario, Clark Patricia
Summary: This study estimated body composition (BC) in Mexican children and adolescents using anthropometry, multifrequency bioimpedance analysis, and dual-energy X-ray absorptiometry, and generated reference values and curves specific to sex and age for this population.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Clinical Neurology
Anders Behrens, Eva Elgh, Goran Leijon, Bo Kristensen, Anders Eklund, Jan Malm
JOURNAL OF NEUROSURGERY
(2020)
Article
Endocrinology & Metabolism
Tomas Vikner, Lars Nyberg, Madelene Holmgren, Jan Malm, Anders Eklund, Anders Wahlin
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Madelene Holmgren, Anders Wahlin, Tora Dunas, Jan MaIm, Anders Eklund
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2020)
Article
Clinical Neurology
Johan Gasslander, Nina Sundstrom, Anders Eklund, Lars-Owe D. Koskinen, Jan Malm
Summary: Male sex, antiplatelet medication, and a lower opening pressure at surgery were identified as risk factors for SDH in iNPH patients with shunts in this Swedish-based registry study. Anti-siphoning devices did not prevent SDH, but allowed for lower opening pressures without increasing the risk of SDH.
JOURNAL OF NEUROSURGERY
(2021)
Article
Neurosciences
Vegard Vinje, Anders Eklund, Kent-Andre Mardal, Marie E. Rognes, Karen-Helene Stoverud
FLUIDS AND BARRIERS OF THE CNS
(2020)
Article
Ophthalmology
Anders Wahlin, Petter Holmlund, Abigail M. Fellows, Jan Malm, Jay C. Buckey, Anders Eklund
Summary: The study revealed that spaceflight can cause optic nerve lengthening and anterior movement of the optic nerve head, which are associated with SANS. Additionally, upward displacement of the optic chiasm was observed, but it could not be linked to SANS.
Article
Multidisciplinary Sciences
Madelene Holmgren, Karen-Helene Stoverud, Laleh Zarrinkoob, Anders Wahlin, Jan Malm, Anders Eklund
Summary: In patients with symptomatic ICA stenosis, a study found pressure differences between the contra- and ipsilateral MCA, which were correlated with flow differences. The MCA pressure laterality obtained through CFD can serve as a promising physiological biomarker for assessing hemodynamic disturbances in these patients.
Article
Clinical Neurology
E. Johansson, L. Zarrinkoob, A. Wahlin, A. Eklund, J. Malm
Summary: Phase-contrast MR imaging is a promising tool for diagnosing carotid near-occlusion, with ICA flow of 110mL/min being 100% sensitive and specific for near-occlusion.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Article
Clinical Neurology
P. Ryska, O. Slezak, A. Eklund, J. Salzer, J. Malm, J. Zizka
Summary: Systematic analysis revealed significant variability in idiopathic normal pressure hydrocephalus imaging biomarkers between patients and healthy controls, especially when measured on different section planes. Strict adherence to the methodology of biomarker assessment is crucial to ensure correct diagnosis.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2021)
Article
Clinical Neurology
Jenny Larsson, Hanna Israelsson, Anders Eklund, Lillemor Lundin-Olsson, Jan Malm
Summary: Patients with idiopathic normal pressure hydrocephalus (INPH) experience issues with falls, fear of falling, and confidence in avoiding falls. While there is improvement after shunt surgery, they still do not reach the levels of the control group. Recurrent fallers are more likely to have low quality of life and symptoms of depression.
Article
Clinical Neurology
Sanna A. Eklund, Hanna Israelsson, Mattias Brunstrom, Karin Forsberg, Jan Malm
Summary: This study found that idiopathic normal pressure hydrocephalus (iNPH) patients treated with CSF shunting had a shorter life expectancy. Cardiovascular comorbidities and fatal falls contributed to the increased mortality in iNPH, suggesting the importance of treating iNPH in supplementary ways to reduce mortality.
JOURNAL OF NEUROLOGY
(2023)
Letter
Ophthalmology
Anders Wahlin, Petter Holmlund, Abigail M. Fellows, Jan Malm, Jay C. Buckey, Anders Eklund