Role of TNF-alpha during central sensitization in preclinical studies

TNF receptor 2 pathway: drug target for autoimmune diseases

(2010) Denise Faustman et al.   NATURE REVIEWS DRUG DISCOVERY

The Reactions of Glial Cells and Endoneurial Macrophages in the Dorsal Root Ganglion and Their Contribution to Pain-Related Behavior After Application of Nucleus Pulposus Onto the Nerve Root in Rats

(2010) Ken-ichi Otoshi et al.   SPINE

Comparison of neuropathic pain and neuronal apoptosis following nerve root or spinal nerve compression

(2009) Miho Sekiguchi et al.   EUROPEAN SPINE JOURNAL

Microglia and neuropathic pain

(2009) Kazuhide Inoue et al.   GLIA

Distribution and tumor necrosis factor-alpha isoform binding specificity of locally administered etanercept into injured and uninjured rat sciatic nerve

(2009) K. Kato et al.   NEUROSCIENCE

Effect of Etanercept, a Tumor Necrosis Factor-Alpha Inhibitor, on Neuropathic Pain in the Rat Chronic Constriction Injury Model

(2009) John M. Zanella et al.   SPINE

Tumor Necrosis Factor-Alpha in the Nucleus Pulposus Mediates Radicular Pain, but Not Increase of Inflammatory Peptide, Associated With Nerve Damage in Mice

(2009) Masaomi Yamashita et al.   SPINE

Tumor necrosis factor-α of Red nucleus involved in the development of neuropathic allodynia

(2008) Xiaoli Li et al.   BRAIN RESEARCH BULLETIN

TNFα and reactive oxygen species in necrotic cell death

(2008) Michael J Morgan et al.   CELL RESEARCH

Effects of Etanercept and Minocycline in a rat model of spinal cord injury

(2008) Fabien Marchand et al.   EUROPEAN JOURNAL OF PAIN

Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model

(2008) Kyung-Min Lee et al.   EUROPEAN JOURNAL OF PAIN

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

Cytokine Mechanisms of Central Sensitization: Distinct and Overlapping Role of Interleukin-1 , Interleukin-6, and Tumor Necrosis Factor-  in Regulating Synaptic and Neuronal Activity in the Superficial Spinal Cord

(2008) Y. Kawasaki et al.   JOURNAL OF NEUROSCIENCE

Exogenous tumor necrosis factor-α rapidly alters synaptic and sensory transmission in the adult rat spinal cord dorsal horn

(2008) Dong-ho Youn et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Systemic Glucocorticoid Therapy Reduces Pain and the Number of Endoneurial Tumor Necrosis Factor-Alpha (TNFα)-Positive Mast Cells in Rats With a Painful Peripheral Neuropathy

(2008) Reiko Hayashi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Selective stimulation of either tumor necrosis factor receptor differentially induces pain behavior in vivo and ectopic activity in sensory neurons in vitro

(2008) M. Schäfers et al.   NEUROSCIENCE

High force reaching task induces widespread inflammation, increased spinal cord neurochemicals and neuropathic pain

(2008) M.B. Elliott et al.   NEUROSCIENCE

Early cytokine gene expression in mouse CNS after peripheral nerve lesion

(2008) Nurcan Üçeyler et al.   NEUROSCIENCE LETTERS

Transient early expression of TNF-α in sciatic nerve and dorsal root ganglia in a mouse model of painful peripheral neuropathy

(2008) Paola Sacerdote et al.   NEUROSCIENCE LETTERS

Contralateral Neuropathic Pain and Neuropathology in Dorsal Root Ganglion and Spinal Cord Following Hemilateral Nerve Injury in Rats

(2008) Satoshi Hatashita et al.   SPINE