期刊
NEUROIMAGE
卷 88, 期 -, 页码 54-60出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.neuroimage.2013.10.028
关键词
Biofeedback; Neurofeedback; MEG; Neural oscillations
资金
- Deutsche Forschungsgemeinschaft (DFG, Germany) [FL 760 2-1]
- Montreal Neurological Institute's National Bank Fellowship (Canada)
- Agence Nationale pour la Recherche (ViMAGINE, France) [ANR-BLAN08-0250]
- Killam Foundation
- Fonds de Recherche du Quebec - Sante
- National Science and Engineering Research Council of Canada
- NIH [2R01EB009048-05]
Biofeedback and brain-computer interfacing using EEG has been receiving continuous and increasing interest. However, the limited spatial resolution of low-density scalp recordings is a roadblock to the unequivocal monitoring and targeting of neuroanatomical regions and physiological signaling. This latter aspect is pivotal to the actual efficiency of neurofeedback procedures, which are expected to engage the modulation of well-identified components of neural activity within and between predetermined brain regions. Our group has previously contributed to demonstrate the principles of real-time magnetoencephalography (MEG) source imaging. Here we show how the technique was further developed to provide healthy subjects with region-specific neurofeedback to modulate successfully predetermined components of their brain activity in targeted brain regions. Overall, our results positively indicate that neurofeedback based on time-resolved MEG imaging has the potential to become an innovative therapeutic approach in neurology and neuropsychiatry. (C) 2014 Elsevier Inc. All rights reserved.
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