Article
Neurosciences
Ke Zeng, Neil M. Drummond, Ayda Ghahremani, Utpal Saha, Suneil K. Kalia, Mojgan Hodaie, Andres M. Lozano, Adam R. Aron, Robert Chen
Summary: Research on the neural substrate for fronto-subthalamic communication during conflict processing has indicated that coordination and information transfer between brain structures are achieved through mechanisms such as theta phase synchronization and theta-gamma phase-amplitude coupling.
Review
Psychology, Multidisciplinary
Mohammed Abubaker, Wiam Al Qasem, Eugen Kvasnak
Summary: Working memory (WM) is crucial for cognitive function, and reduced WM capacity is common in various diseases. The theta-gamma neural code plays a key role in memory representations in multi-item WM. Non-invasive brain stimulation holds promise in improving WM performance by modulating cross-frequency coupling (CFC).
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Psychology, Biological
Sander van Bree, Maria Melcon, Luca D. Kolibius, Casper Kerren, Maria Wimber, Simon Hanslmayr
Summary: Human thought is highly flexible and neuroscience aims to understand cognition by analyzing the intricate patterns in the brain. However, the time format of our data impedes this goal. To overcome this, the Brain Time Toolbox is introduced to retune electrophysiology data in line with the brain's own dynamics and time regime, enabling the study of neural patterns as they unfold in the brain.
NATURE HUMAN BEHAVIOUR
(2022)
Article
Neurosciences
Anna Lena Biel, Tamas Minarik, Paul Sauseng
Summary: The study found that under conditions where participants had to remember multiple templates for successful visual search, there may be a lower level of transient theta-gamma CFS in the posterior region compared to when only one template needs to be remembered. This suggests the concept of sequential attentional templates and provides evidence for matching incoming sensory information with contents from working memory.
Article
Neurosciences
Anna E. Karlsson, Ulman Lindenberger, Myriam C. Sander
Summary: Episodic memory declines with advancing age, especially when forming associations between items and their contexts. This decline is associated with compromised theta-gamma coupling, which is more pronounced in older adults. Theta-gamma coupling closer to the peak of the theta rhythm is beneficial for associative memory formation.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Yuchen Zhou, Alex Sheremet, Jack P. Kennedy, Yu Qin, Nicholas M. DiCola, Sarah D. Lovett, Sara N. Burke, Andrew P. Maurer
Summary: Hippocampal theta and gamma rhythms are thought to be involved in higher cognition, with recent findings suggesting that hippocampal activities can function relatively independently and are not solely driven by gamma oscillations from the entorhinal cortex.
Review
Geriatrics & Gerontology
Daniella B. Victorino, Jean Faber, Daniel J. L. L. Pinheiro, Fulvio A. Scorza, Antonio C. G. Almeida, Alberto C. S. Costa, Carla A. Scorza
Summary: Cross-frequency coupling (CFC) mechanisms play a central role in brain activity, and altered theta-gamma phase-amplitude coupling (PAC) may be one of the earliest EEG signatures of Alzheimer's disease (AD). This can potentially provide clues to the biophysical mechanisms underlying cognitive dysfunction in DS-AD and generate opportunities for identifying EEG-based biomarkers with diagnostic and prognostic utility in DS-AD.
Article
Genetics & Heredity
Michael. G. Mariscal, Elizabeth Berry-Kravis, Joseph D. Buxbaum, Lauren E. Ethridge, Rajna Filip-Dhima, Jennifer H. Foss-Feig, Alexander Kolevzon, Meera. E. Modi, Matthew W. Mosconi, Charles A. Nelson, Craig M. Powell, Paige M. Siper, Latha Soorya, Andrew Thaliath, Audrey Thurm, Bo Zhang, Mustafa Sahin, April R. Levin
Summary: The study found that individuals with PMS show increased alpha-gamma phase bias, particularly over posterior electrodes. Most individuals with PMS demonstrate positive overall phase bias, while typically developing individuals show negative overall phase bias. Among those with PMS, the strength of alpha-gamma phase-amplitude coupling is associated with specific behavioral traits.
Review
Neurosciences
Justin Riddle, Amber McFerren, Flavio Frohlich
Summary: The study highlights the role of cognitive control in guiding motor and perceptual systems towards abstract goals. It shows that prefrontal cortex orchestrates different components of cognitive control via two different cross-frequency coupling modalities.
PROGRESS IN NEUROBIOLOGY
(2021)
Article
Psychology, Biological
Lydia Arana, Maria Melcon, Dominique Kessel, Sandra Hoyos, Jacobo Albert, Luis Carretie, Almudena Capilla
Summary: This study examines the impact of exogenous attention on alpha-band activity, revealing a suppression of alpha activity contralateral to distractor location and highlighting its functional significance in relation to impaired behavioral performance.
Article
Education & Educational Research
Xu Du, Lizhao Zhang, Jui-Long Hung, Hao Li, Hengtao Tang, Yiqian Xie
Summary: The purpose of this study was to analyze the process of online collaborative problem solving through brain-to-brain synchrony. The results showed that the level of brain-to-brain synchrony was higher in the problem-understanding stage compared to the problem-solving stage. Additionally, the level of brain-to-brain synchrony in the problem-solving stage was significantly correlated with task performance. This indicates that brain-to-brain synchrony can serve as an effective indicator of collaborative problem solving and individual interaction.
INTERNATIONAL JOURNAL OF EDUCATIONAL TECHNOLOGY IN HIGHER EDUCATION
(2022)
Article
Multidisciplinary Sciences
Harish Gunasekaran, Leila Azizi, Virginie van Wassenhove, Sophie K. Herbst
Summary: This study used magnetoencephalography (MEG) to investigate the brain oscillations in humans during rest. The researchers found that only the resting state condition showed spectral peaks in the delta frequency range that could be interpreted as endogenously periodic neural dynamics.
SCIENTIFIC REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Francesco Di Gregorio, Jelena Trajkovic, Cristina Roperti, Eleonora Marcantoni, Paolo Di Luzio, Alessio Avenanti, Gregor Thut, Vincenzo Romei
Summary: This study reveals the role of alpha oscillations in human conscious experience. Controlling alpha frequency with rTMS can influence perceptual accuracy, while controlling alpha amplitude can affect the ability to distinguish between correct and incorrect decisions in subjective confidence judgments.
Review
Behavioral Sciences
Boris Yakubov, Sushmit Das, Reza Zomorrodi, Daniel M. Blumberger, Peter G. Enticott, Melissa Kirkovski, Tarek K. Rajji, Pushpal Desarkar
Summary: Cross-frequency coupling (CFC) has been found to show measurable differences between disease states and healthy controls in psychiatric disorders, as well as variation within the same psychiatric disorders in different brain regions. Standardized methodologies should be established and utilized in future research to understand the neuropathophysiology associated with psychiatric disorders.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Neurosciences
Torge Dellert, Miriam Mueller-Bardorff, Insa Schlossmacher, Michael Pitts, David Hofmann, Maximilian Bruchmann, Thomas Straube
Summary: Conscious visual perception is associated with early processing in stimulus-specific sensory brain areas and occipitotemporal processes, while task-related processes lead to widespread brain activations, including late frontoparietal activity.
JOURNAL OF NEUROSCIENCE
(2021)
Editorial Material
Neurosciences
Ian C. Fiebelkorn
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Guiomar Niso, Laurens R. Krol, Etienne Combrisson, A. Sophie Dubarry, Madison A. Elliott, Clement Francois, Yseult Hejja-Brichard, Sophie K. Herbst, Karim Jerbi, Vanja Kovic, Katia Lehongre, Steven J. Luck, Manuel Mercier, John C. Mosher, Yuri G. Pavlov, Aina Puce, Antonio Schettino, Daniele Schon, Walter Sinnott-Armstrong, Bertille Somon, Andela Soskic, Suzy J. Styles, Roni Tibon, Martina G. Vilas, Marijn van Vliet, Maximilien Chaumon
Summary: Good Scientific Practice (GSP) refers to rules, recommendations, and guidelines that help scientists produce high-quality work and share it with the community. In the context of MEEG research, GSP includes technical standards and guidelines, as well as a consideration of personal, organizational, and societal factors.
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Kevin A. Mazurek, Edward G. Freedman
Summary: This study investigates the effects of pairing a cognitive task with walking in young adults. The preliminary findings suggest that some participants improve in cognitive task performance while walking, while others do not. Neural activity changes associated with performance improvement may have potential implications for assessing cognitive decline in aging and neurodegeneration.
Article
Neurosciences
Ian C. Fiebelkorn
Summary: Recent research suggests periodicity in attention-related sampling and switching, with initial findings from behavioral studies. However, widely used approaches to testing for rhythms in behavioral time series can misclassify consistent aperiodic patterns as periodic patterns. Evidence for rhythmic attention is not limited to behavioral data.
JOURNAL OF COGNITIVE NEUROSCIENCE
(2023)
Article
Neurosciences
Elizabeth M. Sachse, Adam C. Snyder
Summary: In this study, we quantitatively characterized the distribution of attention modulation of firing rates across populations of V4 neurons. Neurons exhibited a continuum of time-varying attention effects, showing both enhanced stimulus responses and depressed spontaneous activity or vice versa. We found an interdependence among neural attention effects, neuron type, and population coupling, suggesting a relationship between specific neuronal properties and attention effects.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Miral Abdalaziz, Zach Redding, Ian C. Fiebelkorn
Summary: Selective attention is characterized by alternating states that isolate function-specific neural activity in time. We tested the hypothesis that rhythmic temporal coordination can also prevent representational conflicts during working memory. The results support the idea that rhythmic temporal coordination is a general mechanism for preventing conflicts and inform models of working memory organization.
Article
Neurosciences
Hayden Scott, Klaus Wimmer, Tatiana Pasternak, Adam C. C. Snyder
Summary: Neurons in the primate middle temporal area and lateral prefrontal cortex signal visual motion information and support memory-guided comparisons of visual motion direction. The two areas are directly connected and show changes in stimulus coding with altered task demands. Active participation in a motion direction comparison task affects both sensory and nonsensory activity in middle temporal neurons, with some neurons becoming less selective for motion direction and showing increased signaling for cognitive aspects of the task. This suggests a division of labor in the middle temporal area, with different populations of neurons responding to sensory and cognitive signals.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Kathryn-Mary Wakim, John J. Foxe, Sophie Molholm
Summary: Motor atypicalities are common in autism spectrum disorder (ASD) and research on basic motor processing in autistic individuals is surprisingly sparse. In this study, we analyzed EEG data from a large sample of autistic and neurotypical children and adolescents, revealing clear motor-related neural responses in ASD, but with subtle differences compared to typically developing participants. Group differences were most prominent in the youngest group of children (age 6-9), suggesting the need for further investigations in younger children.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Emily J. Knight, Edward G. Freedman, Evan J. Myers, Alaina S. Berruti, Leona A. Oakes, Cody Zhewei Cao, Sophie Molholm, John J. Foxe
Summary: Individuals with autism spectrum disorder exhibit atypical sensory perception, which is not fully understood. One proposed mechanism is an imbalance in higher-order feedback inputs during sensory perception, resulting in a preference for local object features. This study investigated this theory using visual evoked potentials and found that autistic children had attenuated responses to illusory contours compared to neurotypical controls. These findings suggest that weakened predictive feedback processes may contribute to the visual processing anomalies seen in autism.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Emma P. Mantel, George Kassis, Edward G. Freedman
Summary: Combining walking with a cognitive task can improve performance in younger and older adults, with the former benefiting cognitively while the latter experiencing motor decline. EEG activity and behavioral responses during walking were correlated with increased response accuracy, while slower walking speeds and changes in EEG activity were associated with aging.
Article
Ophthalmology
James Loughman, Emmanuel Kobia-Acquah, Gareth Lingham, John Butler, Ekaterina Loskutova, David A. Mackey, Samantha S. Y. Lee, Daniel I. Flitcroft
Summary: The study investigates the efficacy and safety of 0.01% atropine eye drops in managing myopia progression in a predominantly White, European population. The results show that atropine is effective in slowing axial elongation and is well-tolerated in this population. However, treatment efficacy varies by ethnicity and degree of COVID-19 restriction exposure.
ACTA OPHTHALMOLOGICA
(2023)
Editorial Material
Neurosciences
Michael Willis, Megan R. Carey, John J. Foxe, Jackie Jones, Nathan Smith, Vidita Vaidya
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Eleni Patelaki, John J. Foxe, Amber L. McFerren, Edward G. Freedman
Summary: This study investigates the neural mechanisms underlying increased cognitive load while walking. The findings suggest that the difficulty of the cognitive task does not affect response accuracy, speed, or gait consistency, but it does lead to changes in EEG components.
Article
Neurosciences
Emily L. Isenstein, Edward G. Freedman, Jiayi Xu, Ian A. DeAndrea-Lazarus, John J. Foxe
Summary: This study evaluated electrophysiological discrimination of parametric somatosensory stimuli in healthy young adults to understand how the brain processes the duration of tactile information. The results showed that participants did not electrophysiologically discriminate between 100 and 115 ms, but they exhibited distinct electrophysiological responses when the deviant stimuli were 130, 145, and 160 ms. These findings contribute to a better understanding of tactile sensitivity in different clinical conditions.
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.