Article
Neurosciences
Simone P. Haller, Gang Chen, Elizabeth R. Kitt, Ashley R. Smith, Joel Stoddard, Rany Abend, Sofia Cardenas, Olga Revzina, Daniel Coppersmith, Ellen Leibenluft, Melissa A. Brotman, Daniel S. Pine, David Pagliaccio
Summary: Assessing and improving test-retest reliability is critical for addressing concerns about replicability in fMRI studies. This study examined the influence of scanner and task-related factors on the reliability of neural response to face-emotion viewing. The results showed that activated regions had higher reliability than non-activated regions, and contrasts involving distinct visual stimuli and cognitive demands had greater reliability.
HUMAN BRAIN MAPPING
(2022)
Article
Audiology & Speech-Language Pathology
Megan C. Fitzhugh, Sydney Y. Schaefer, Leslie C. Baxter, Corianne Rogalsky
Summary: Cognitive abilities and brain networks play crucial roles in older adults' ability to comprehend speech in noisy backgrounds. Hearing loss and working memory mainly affect speech comprehension abilities related to energetic masking, while processing speed and functional connectivity are more associated with informational masking conditions.
LANGUAGE COGNITION AND NEUROSCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Yuxin Li, Lei Tian, Li-Li Guo, Yiran Hao, Ying Jie
Summary: This study evaluated the repeatability and reproducibility of 36 DCR parameters and bIOP parameters derived from Corvis ST in healthy eyes, and investigated their relationship with demographic and ocular characteristics.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biochemical Research Methods
Jun Chen, Xianyang Zhang
Summary: Due to the sparsity and high dimensionality, microbiome data are often summarized into pairwise distances to capture compositional differences and gain biological insights through analyzing the distance matrix in relation to covariates. This study extends the traditional intraclass correlation coefficient (ICC) to distance measures, proposing a distance-based ICC (dICC) and demonstrating its effectiveness through the application of experimental data.
Article
Neurosciences
Basil C. Preisig, Lars Riecke, Alexis Hervais-Adelman
Summary: Which processes in the human brain lead to the categorical perception of speech sounds? Investigation of this question is hampered by the fact that categorical speech perception is normally confounded by acoustic differences in the stimulus. By using ambiguous sounds, however, it is possible to dissociate acoustic from perceptual stimulus representations. This study found that various brain regions, including left perisylvian regions, left inferior frontal regions, left supplementary motor cortex, and right motor and somatosensory regions, represent listeners' syllable report irrespective of stimulus acoustics. These regions are outside of what is traditionally regarded as auditory or phonological processing areas.
Article
Neurosciences
Fatma Deniz, Christine Tseng, Leila Wehbe, Tom Dupre la Tour, Jack L. Gallant
Summary: The meaning of words in natural language depends on context, yet most neuroimaging studies of word meaning use isolated words and sentences with little context. This study used fMRI to investigate the effects of context on brain activity and the representation of semantic information. The results showed that stimuli with more context elicited stronger brain responses and increased representation of semantic information in multiple brain regions. The findings suggest that neuroimaging studies using isolated stimuli may not generalize well to natural language used in daily life.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Biology
Sanne ten Oever, Sara Carta, Greta Kaufeld, Andrea E. Martin
Summary: Despite the absence of a one-to-one acoustic phrase marker, linguistic phrases are still tracked in sentences, suggesting an automatic tracking of abstract linguistic structure by the brain. The study also found that the tracking of phrasal rates in the inferior frontal gyrus (IFG) is independent of the presence of linguistic structure and is stronger during word-combination tasks.
Article
Neuroimaging
Diede Fennema, Owen O'Daly, Gareth J. Barker, Jorge Moll, Roland Zahn
Summary: This study investigated the internal consistency of self-blame-related fMRI measures, finding fair reliability for simple measures but poor reliability for complex measures. While complex measures showed low internal consistency at the individual level, robust activation was observed at the group level. This highlights the need for the development of functional connectivity measures that strike a better balance between reliability and validity for future clinical applications.
NEUROIMAGE-CLINICAL
(2021)
Article
Behavioral Sciences
Jin Wang, Neelima Wagley, Mabel L. Rice, James R. Booth
Summary: The study found that children aged 5 to 6 exhibited semantic specialization in the temporal lobe, while children aged 7 to 8 showed both semantic and syntactic specialization in both the temporal and frontal lobes. This suggests a developmental progression in language processing from temporal to frontal regions in children.
Article
Neurosciences
Guangyao Zhang, Yangwen Xu, Meimei Zhang, Shaonan Wang, Nan Lin
Summary: The study found that the social semantic network not only represents the social meanings of words, but also accumulates social meanings from texts. The network shows a stronger social semantic effect in sentence and narrative reading, suggesting that social semantic contents can be integrated and accumulated within the network.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2021)
Article
Neurosciences
Sara Farshchi, Annika Andersson, Joost van de Weijer, Carita Paradis
Summary: While little is known about the processing of negation, previous studies have mainly focused on written stimuli, making it difficult to understand how it is processed in spoken language. We developed an auditory paradigm based on a visual study and found that processing costs differed between the two modalities, suggesting that negated forms in spoken language are processed with less effort. The natural flow of spoken language reduces variability in processing and results in clearer ERP patterns.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Neurosciences
Andrew James Anderson, Douwe Kiela, Jeffrey R. Binder, Leonardo Fernandino, Colin J. Humphries, Lisa L. Conant, Rajeev D. S. Raizada, Scott Grimm, Edmund C. Lalor
Summary: Recent studies have used vector models of word meaning derived from patterns of word co-occurrence in text corpora to explain brain activation elicited by sentences, mapping out semantic representation across a distributed brain network spanning temporal, parietal, and frontal cortex. However, it remains unclear whether activation patterns within regions reflect unified representations of sentence-level meaning. To address this issue, a recurrent deep artificial neural network was used to encode sentences and predict fMRI activation elements, showing that propositional sentence-level meaning is represented within and across multiple cortical regions.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Kexu Zhang, Wen Shi, Chang Wang, Yamin Li, Zhian Liu, Tun Liu, Jing Li, Xiangguo Yan, Qiang Wang, Zehong Cao, Gang Wang
Summary: The study demonstrates that microstate analysis is more reliable with higher electrode densities in investigating different brain states, and the use of a small number of channels is not recommended for obtaining consistent results.
Article
Anatomy & Morphology
Lanfang Liu, Xiaowei Ding, Hehui Li, Qi Zhou, Dingguo Gao, Chunming Lu, Guosheng Ding
Summary: Studies have found that older adults have deficits in neural coupling related to speech understanding, which may be associated with their decreased ability to achieve neural alignment with others.
BRAIN STRUCTURE & FUNCTION
(2021)
Article
Clinical Neurology
Patrick Bach, Holger Hill, Iris Reinhard, Theresa Gaedeke, Falk Kiefer, Tagrid Lemenager
Summary: The self-concept, defined as beliefs about oneself, showed good test-retest reliability in neural brain activation when comparing self, familiar, and unknown person contrasts, but lower reliability when comparing self to familiar/unknown person, likely due to high correlation between contrast conditions. Further research on self-evaluation should consider local reliability differences in the brain and employ methods to overcome these limitations.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Review
Engineering, Biomedical
Eric A. Nauman, Thomas M. Talavage, Paul S. Auerbach
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 22
(2020)
Article
Biochemical Research Methods
Ho-Ching (Shawn) Yang, Zhenhu Liang, Nicole L. Vike, Taylor Lee, Joseph Rispoli, Eric A. Nauman, Thomas M. Talavage, Yunjie Tong
JOURNAL OF BIOPHOTONICS
(2020)
Article
Endocrinology & Metabolism
Jinxia (Fiona) Yao, Ho-Ching (Shawn) Yang, James H. Wang, Zhenhu Liang, Thomas M. Talavage, Gregory G. Tamer, Ikbeom Jang, Yunjie Tong
Summary: This study developed a novel analytical method to accurately calculate the arrival time of elevated CO2 at each voxel and used 26 candidate hemodynamic response functions to quantitatively describe the temporal brain reactions to a CO2 stimulus. By improving the traditional method, this approach successfully mapped three perfusion-related parameters: the relative arrival time of blood, the hemodynamic response function, and CVR during a CO2 challenge.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2021)
Article
Critical Care Medicine
Yufen Chen, Amy A. Herrold, Alexa E. Walter, James L. Reilly, Peter H. Seidenberg, Eric A. Nauman, Thomas Talavage, David J. Vandenbergh, Semyon M. Slobounov, Hans C. Breiter
Summary: The study reveals that athletes in collision sports can experience significant brain changes even without concussion, due to exposure to head acceleration events. The relationship between TPH2 gene, regional cerebral blood flow, and VR motor performance varies between T-carriers and CC homozygotes both pre-season and across a single football season.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Neurosciences
Javier Gonzalez-Castillo, Julia W. Y. Kam, Colin W. Hoy, Peter A. Bandettini
Summary: Resting-state fMRI reveals brain dynamics in an unconstrained environment where subjects let their minds wander freely, navigating a rich space of cognitive and perceptual states. How ongoing experience influences rsfMRI summary metrics is unclear, but may uniquely contribute to differences within and between subjects. To understand this influence, standardized, temporally resolved, scientifically validated first-person descriptions of experiences are necessary.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Clinical Neurology
Hrishikesh M. Rao, Sophia Yuditskaya, James R. Williamson, Trina R. Vian, Joseph J. Lacirignola, Trey E. Shenk, Thomas M. Talavage, Kristin J. Heaton, Thomas F. Quatieri
Summary: The study investigates the potential for oculomotor features to complement existing diagnostic tools and found significant correlations between eye movements, ONSD, and ImPACT scores, demonstrating the capability of oculomotor features to capture neurological changes.
FRONTIERS IN NEUROLOGY
(2021)
Editorial Material
Neurosciences
Remi Gau, Stephanie Noble, Katja Heuer, Katherine L. Bottenhorn, Isil P. Bilgin, Yu-Fang Yang, Julia M. Huntenburg, Johanna M. M. Bayer, Richard A. I. Bethlehem, Shawn A. Rhoads, Christoph Vogelbacher, Valentina Borghesani, Elizabeth Levitis, Hao-Ting Wang, Sofie Van den Bossche, Xenia Kobeleva, Jon Haitz Legarreta, Samuel Guay, Selim Melvin Atay, Gael P. Varoquaux, Dorien C. Huijser, Malin S. Sandstrom, Peer Herholz, Samuel A. Nastase, AmanPreet Badhwar, Guillaume Dumas, Simon Schwab, Stefano Moia, Michael Dayan, Yasmine Bassil, Paula P. Brooks, Matteo Mancini, James M. Shine, David O'Connor, Xihe Xie, Davide Poggiali, Patrick Friedrich, Anibal S. Heinsfeld, Lydia Riedl, Roberto Toro, Cesar Caballero-Gaudes, Anders Eklund, Kelly G. Garner, Christopher R. Nolan, Damion V. Demeter, Fernando A. Barrios, Junaid S. Merchant, Elizabeth A. McDevitt, Robert Oostenveld, R. Cameron Craddock, Ariel Rokem, Andrew Doyle, Satrajit S. Ghosh, Aki Nikolaidis, Olivia W. Stanley, Eneko Urunuela
Summary: Brainhack is an innovative meeting format that promotes scientific collaboration and education in an open, inclusive environment, complementing conventional formats to augment scientific progress.
Article
Multidisciplinary Sciences
Yukai Zou, Wenbin Zhu, Ho-Ching Yang, Ikbeom Jang, Nicole L. Vike, Diana O. Svaldi, Trey E. Shenk, Victoria N. Poole, Evan L. Breedlove, Gregory G. Tamer, Larry J. Leverenz, Ulrike Dydak, Eric A. Nauman, Yunjie Tong, Thomas M. Talavage, Joseph V. Rispoli
Summary: Human brains develop differently across the life span and specialized brain atlases targeting specific populations, such as adolescent collision-sport athletes, are crucial for accurate and meaningful research on neuroanatomy and brain health.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Bradley Fitzgerald, Jinxia Fiona Yao, Thomas M. Talavage, Lia M. Hocke, Blaise deB Frederick, Yunjie Tong
Summary: A carpet plot is a tool for studying LFOs in resting state fMRI data, with the use of a slope-detection algorithm to identify and calculate propagation times. The visualization of LFOs propagation in carpet plots can be automatically identified as tilted lines of intensity change. Resting state carpet plots produce edge transit times similar to those of DSC carpet plots.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
James R. Williamson, Doug Sturim, Trina Vian, Joseph Lacirignola, Trey E. Shenk, Sophia Yuditskaya, Hrishikesh M. Rao, Thomas M. Talavage, Kristin J. Heaton, Thomas F. Quatieri
Summary: Repeated subconcussive blows can have long lasting effects on cognitive functioning, making unobtrusive measures crucial for identifying individuals at risk. The study investigates the potential of passive measurements of fine motor movements and resting state brain activity to complement existing diagnostic tools, such as the ImPACT test. Results show promise in predicting cognitive performance and detecting deficits associated with subconcussive events through passive monitoring.
FRONTIERS IN NEUROLOGY
(2021)
Editorial Material
Neurosciences
Javier Gonzalez-Castillo
Summary: The authors propose a new framework for studying the natural wanderings of the living brain, based on geophysical concepts of standing and traveling waves.
NATURE NEUROSCIENCE
(2022)
Article
Neurosciences
Javier Gonzalez-Castillo, Isabel S. Fernandez, Daniel A. Handwerker, Peter A. Bandettini
Summary: Wakefulness levels can impact estimates of functional connectivity and may confound resting-state fMRI studies. Recent research has found fluctuations in the fourth ventricle during sleep, which are hypothesized to be related to CSF inflow and correlate with the global signal. Analyzing these fluctuations can help evaluate wakefulness levels and improve our understanding of functional connectivity during sleep.
Article
Neurosciences
Joshua B. Teves, Javier Gonzalez-Castillo, Micah Holness, Megan Spurney, Peter A. Bandettini, Daniel A. Handwerker
Summary: Designing and executing a good QC process is crucial for robust and reproducible science. As fMRI research trends towards larger sample sizes and automated processing, it is important to not overlook information about data acquisition and quality. This article provides an introduction to researchers who are familiar with fMRI but lack hands-on QC training, explaining the importance of good QC processes and demonstrating key steps using AFNI software and an openly shared dataset.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Neurosciences
Paul A. Taylor, Richard C. Reynolds, Vince Calhoun, Javier Gonzalez-Castillo, Daniel A. Handwerker, Peter A. Bandettini, Amanda F. Mejia, Gang Chen
Summary: Neuroimaging studies often display only a small fraction of the collected data, which hides important information and leads to issues of selection bias and irreproducibility. Instead, it is suggested to highlight as many results as possible through visualization to improve scientific communication and understanding.
Article
Engineering, Biomedical
Taylor Lee, Roy Lycke, Joshua Auger, Jacob Music, Michael Dziekan, Sharlene Newman, Thomas Talavage, Larry Leverenz, Eric Nauman
Summary: The study aimed to evaluate the impact of repetitive head traumas on athletes in contact sports, finding that the type of sport has a greater influence on head acceleration event characteristics than the level of play.
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
(2021)